Domenico Tamburrino
University College London
Neuroendocrine tumorsPancreatic cancerDiabetes mellitusGeneral surgeryMedicine
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Publications 74
#1Stefano Partelli (UniSR: Vita-Salute San Raffaele University)H-Index: 29
#2Domenico Tamburrino (Sapienza University of Rome)H-Index: 13
Last. Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 79
view all 10 authors...
Abstract Background Postoperative acute pancreatitis (POAP) can be a possible cause of postoperative pancreatic fistula (POPF). The present study aimed to evaluate the role of clinically-relevant POAP (CR-POAP), defined according to different cut-offs of postoperative amylase (AMS) values and C-reactive protein (CRP), in the development of clinically relevant POPF (CR-POPF) after pancreaticoduodenectomy (PD). Methods Data from 610 patients who underwent PD (2015–2018) were analyzed. Patients wer...
#1Michele Reni (UniSR: Vita-Salute San Raffaele University)H-Index: 46
#2Umberto Peretti (UniSR: Vita-Salute San Raffaele University)H-Index: 3
Last. Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 79
view all 11 authors...
Defining optimal treatment duration in patients with resectable pancreatic ductal adenocarcinoma (PDAC) receiving primary chemotherapy is an unmet need. The role of time to CA19-9 nadir and of nadir magnitude was explored in this study. The databases of our institution’s prospective trials were queried to speculate on the time to maximum chemotherapy response. Patients with pathologically proven, metastatic (N = 356) or non-metastatic non-resected (N = 163) PDAC and elevated baseline (> 34 UI/mL...
#1Domenico TamburrinoH-Index: 13
#2Stefano CrippaH-Index: 41
Last. Gabriele CapursoH-Index: 37
view all 7 authors...
Abstract Background Previous studies on statins’ effect on survival of patients with pancreatic ductal adenocarcinoma (PDAC) report conflicting results. Aims To evaluate the association between statin use and PDAC patients’ survival. Methods A systematic review and meta-analysis was performed including case-control, cohort studies and randomized controlled trials assessing the association between statin use and survival in PDAC patients. Pooled HRs with 95%CIs were calculated using random effect...
1 CitationsSource
#1Giuseppe MazzaH-Index: 9
#2A TeleseH-Index: 1
Last. Krista RomboutsH-Index: 15
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An altered liver microenvironment characterized by a dysregulated extracellular matrix (ECM) supports the development and progression of hepatocellular carcinoma (HCC). The development of experimental platforms able to reproduce these physio-pathological conditions is essential in order to identify and validate new therapeutic targets for HCC. The aim of this work was to validate a new in vitro model based on engineering three-dimensional (3D) healthy and cirrhotic human liver scaffolds with HCC...
1 CitationsSource
#1Nicolò PecorelliH-Index: 14
#2Michele Pagnanelli (UniSR: Vita-Salute San Raffaele University)H-Index: 1
Last. Gianpaolo BalzanoH-Index: 30
view all 12 authors...
Introduction: Previous studies show encouraging oncologic outcomes for neoadjuvant chemotherapy (NACT) in the setting of pancreatic ductal adenocarcinoma (PDAC). However, recent literature reported an increased clinical burden in patients undergoing pancreaticoduodenectomy (PD) following NACT. Therefore, the aim of our study was to assess the impact of NACT on postoperative outcomes and recovery after PD. Methods: A retrospective propensity score-matched study was performed including all patient...
#1Paolo Giuffrida (UNIPV: University of Pavia)
#2M. Curti (UNIPV: University of Pavia)H-Index: 1
Last. Giuseppe Mazza (UCL: University College London)H-Index: 9
view all 19 authors...
#1Umberto Peretti (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Michele Reni (UniSR: Vita-Salute San Raffaele University)H-Index: 46
Last. Luca Gianni (UniSR: Vita-Salute San Raffaele University)H-Index: 66
view all 10 authors...
#1Stefano PartelliH-Index: 29
#2Michele MazzaH-Index: 2
Last. Massimo FalconiH-Index: 79
view all 7 authors...
Abstract Background International guidelines suggest a watchful strategy for small nonfunctioning pancreatic neuroendocrine tumors. The aim of this study was to evaluate the management and indications for surgery in patients with asymptomatic nonfunctioning pancreatic neuroendocrine tumors ≤2 cm. Methods Patients with asymptomatic, incidental, sporadic nonfunctioning pancreatic neuroendocrine tumors ≤2 cm without nodal or distant metastases were included (2012–2016). A comparison between active ...
4 CitationsSource
#1Livia ArchibugiH-Index: 8
Last. Paolo Giorgio ArcidiaconoH-Index: 29
view all 10 authors...