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John Vontas
Foundation for Research & Technology – Hellas
190Publications
42H-index
6,877Citations
Publications 189
Newest
#1Vincent Corbel (IRD: Institut de recherche pour le développement)H-Index: 39
#2Claire Durot (IRD: Institut de recherche pour le développement)H-Index: 1
Last.David Weetman (LSTM: Liverpool School of Tropical Medicine)H-Index: 27
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The past 40 years have seen a dramatic emergence of epidemic arboviral diseases transmitted primarily by mosquitoes. The frequency and magnitude of the epidemics, especially those transmitted by urban Aedes species, have progressively increased over time, accelerating in the past 10 years. To reduce the burden and threat of vector-borne diseases, the World Health Organization (WHO) has recently adopted the Global Vector Control Response (GVCR) in order to support countries in implementing effect...
1 CitationsSource
#1Konstantinos Mavridis (FORTH: Foundation for Research & Technology – Hellas)H-Index: 13
#2Nadja Wipf (University of Basel)H-Index: 2
Last.John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
view all 6 authors...
Background Metabolic resistance of the major malaria vector Anopheles gambiae (s.l.) to insecticides is operationally significant, particularly in combination with target site resistance. However, detection of metabolic resistance is not trivial and relies on laborious bioassays, unspecific biochemical methods, or sophisticated and expensive molecular approaches using transcriptomics.
2 CitationsSource
#1Isabelle Dusfour (Pasteur Institute)H-Index: 21
#2John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
Last.Fabrice Chandre (IRD: Institut de recherche pour le développement)H-Index: 46
view all 11 authors...
Background The landscape of mosquito-borne disease risk has changed dramatically in recent decades, due to the emergence and reemergence of urban transmission cycles driven by invasive Aedes aegypti and Ae. albopictus. Insecticide resistance is already widespread in the yellow fever mosquito, Ae. Aegypti; is emerging in the Asian tiger mosquito Ae. Albopictus; and is now threatening the global fight against human arboviral diseases such as dengue, yellow fever, chikungunya, and Zika. Because the...
2 CitationsSource
#1Peng Wei (UGent: Ghent University)
#2Peter Demaeght (UGent: Ghent University)H-Index: 5
Last.Thomas Van Leeuwen (UGent: Ghent University)H-Index: 37
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#1Verena PichlerH-Index: 4
Last.Beniamino CaputoH-Index: 17
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1 CitationsSource
#1Evangelia Katsavou (UoA: National and Kapodistrian University of Athens)
#2Spyros Vlogiannitis (UoA: National and Kapodistrian University of Athens)
Last.John Vontas (UoA: National and Kapodistrian University of Athens)H-Index: 42
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#1Roland BamouH-Index: 3
view all 7 authors...
A key factor affecting malaria vector control efforts in Cameroon is the rapid expansion of insecticide resistance in Anopheles gambiae s.l (An. gambiae) populations; however, mechanisms involved in insecticide resistance in forest mosquito populations are still not well documented yet. The present study was conducted to screen molecular mechanisms conferring insecticide resistance in An. gambiae s.l. populations from the South Cameroon forest region. WHO bioassays were conducted with F0 An. gam...
1 CitationsSource
#1Raul Narciso C. Guedes (UFV: Universidade Federal de Viçosa)H-Index: 42
#2Emmanouil RoditakisH-Index: 15
Last.Ralf Nauen (Bayer)H-Index: 56
view all 9 authors...
The South American tomato pinworm, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae), is an invasive pest difficult to control. Insecticide application is quite common and remains the prevalent control method particularly in open-field cultivation systems. As a result, insecticide resistance to many chemical classes of insecticides has been described both in South America and in Europe. The development of insecticide resistance is relatively fast in this species, and the main mechanisms involve...
5 CitationsSource
#1Amy Lynd (LSTM: Liverpool School of Tropical Medicine)H-Index: 11
#2Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
Last.Gareth Lycett (LSTM: Liverpool School of Tropical Medicine)H-Index: 16
view all 7 authors...
Oenocytes are an insect cell type having diverse physiological functions ranging from cuticular hydrocarbon (CHC) production to insecticide detoxification that may impact their capacity to transmit pathogens. To develop functional genetic tools to study Anopheles gambiae oenocytes, we have trapped an oenocyte enhancer to create a transgenic mosquito Gal4 driver line that mediates tissue-specific expression. After crossing with UAS-reporter lines, An. gambiae oenocytes are fluorescently tagged th...
1 CitationsSource
#1John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
#2Konstantinos Mavridis (FORTH: Foundation for Research & Technology – Hellas)H-Index: 13
Abstract Insecticide resistance is a large and growing problem for the control of mosquito disease vectors. The World Health Organization (WHO) established the Global Plan for Insecticide Resistance Management (GPIRM) in 2012. In that context, both classical and molecular tools, as well as entomological databases and decision support platforms have been developed and used for IRM. Despite major advances in the molecular elucidation of resistance mechanisms and the development of diagnostic tools...
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