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Catriona Syme
University of Toronto
40Publications
13H-index
644Citations
Publications 40
Newest
Published on Sep 11, 2018in International Journal of Obesity 5.16
Catriona Syme13
Estimated H-index: 13
(U of T: University of Toronto),
Stephanie Pelletier (U of T: University of Toronto)+ 14 AuthorsG. Bruce Pike57
Estimated H-index: 57
(U of C: University of Calgary)
Life-long maintenance of brain health is important for the prevention of cognitive impairment in older age. Low-grade peripheral inflammation associated with excess visceral fat (VF) may influence brain structure and function. Here we examined (i) if this type of inflammation is associated with altered white-matter (WM) microstructure and lower cognitive functioning in adolescents, and (ii) if recently identified circulating glycerophosphocholines (GPCs) can index this type of inflammation and a...
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Published on Apr 3, 2019in The Journal of Clinical Endocrinology and Metabolism 5.79
Jean Shin6
Estimated H-index: 6
(U of T: University of Toronto),
Catriona Syme13
Estimated H-index: 13
(U of T: University of Toronto)
+ 5 AuthorsZdenka Pausova41
Estimated H-index: 41
(U of T: University of Toronto)
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Published on Jan 1, 2019
Catriona Syme13
Estimated H-index: 13
,
Jean Shin6
Estimated H-index: 6
+ 4 AuthorsZdenka Pausova41
Estimated H-index: 41
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Published on Jan 1, 2019
Catriona Syme13
Estimated H-index: 13
,
Jean Shin6
Estimated H-index: 6
+ 4 AuthorsZdenka Pausova41
Estimated H-index: 41
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Published on Dec 1, 2017in American Journal of Human Genetics 8.86
Melissa Richard8
Estimated H-index: 8
(University of Texas Health Science Center at Houston),
Tianxiao Huan22
Estimated H-index: 22
+ 110 AuthorsPei-Chien Tsai13
Estimated H-index: 13
('KCL': King's College London)
Genome-wide association studies have identified hundreds of genetic variants associated with blood pressure (BP), but sequence variation accounts for a small fraction of the phenotypic variance. Epigenetic changes may alter the expression of genes involved in BP regulation and explain part of the missing heritability. We therefore conducted a two-stage meta-analysis of the cross-sectional associations of systolic and diastolic BP with blood-derived genome-wide DNA methylation measured on the Inf...
11 Citations Source Cite
Published on Sep 1, 2017in Hypertension 6.82
Catriona Syme13
Estimated H-index: 13
,
Jean Shin6
Estimated H-index: 6
+ 7 AuthorsZdenka Pausova41
Estimated H-index: 41
Hypertension is a leading cause of death. Sex differences in blood pressure (BP) and hypertension prevalence emerge during adolescence and remain throughout reproductive age. Sex differences in BP-underlying hemodynamics, i.e., in the relative contributions of stroke volume (SV), total peripheral resistance (TPR) and heart rate (HR) to BP, have not been investigated in these age categories in a population-based setting. We studied a cohort of 1,347 individuals, including 911 adolescents (12-18 y...
Published on Apr 1, 2017in Pediatric Obesity 3.98
Greg D. Wells7
Estimated H-index: 7
,
Laura Banks8
Estimated H-index: 8
+ 6 AuthorsHamiltonJill29
Estimated H-index: 29
(U of T: University of Toronto)
Background Obesity is associated with cardiometabolic disturbances, which may have significant implications for musculoskeletal health and exercise tolerance. Objective We sought to determine the association between muscle structure, function, and metabolism in adolescents across the weight spectrum. Methods This cross-sectional case–control study included overweight and obese participants (n = 24) 8–18 years of age with a body mass index (BMI) ≥ 85th percentile for age and gender, and non-obese...
2 Citations Source Cite
Published on Jan 2, 2017in Journal of Neuroscience Research 2.66
Tomáš Paus82
Estimated H-index: 82
(MIND Institute),
Angelita Pui-Yee Wong3
Estimated H-index: 3
(U of T: University of Toronto)
+ 1 AuthorsZdenka Pausova41
Estimated H-index: 41
(U of T: University of Toronto)
This Mini-Review describes sex differences in 66 quantitative characteristics of the brain and body measured in a community-based sample of 1,024 adolescents 12–18 years of age, members of the Saguenay Youth Study. Using an extensive phenotyping protocol, we have obtained measures in a number of domains, including brain structure, cognition, mental health, substance use, body composition, metabolism, cardiovascular reactivity, and life style. For each measure, we provide estimates of effect size...
13 Citations Source Cite
Published on Nov 22, 2016in Circulation 18.88
Catriona Syme13
Estimated H-index: 13
,
Simon Czajkowski1
Estimated H-index: 1
+ 13 AuthorsLisa J. Strug25
Estimated H-index: 25
Background: Glycerophosphocholine (GPC) metabolites modulate atherosclerosis and thus risk for cardiovascular disease (CVD). Preclinical CVD may start during adolescence. Here, we used targeted serum lipidomics to identify a new panel of GPCs, and tested whether any of these GPCs are associated, in adolescence, with classical risk factors of CVD, namely excess visceral fat (VF), elevated blood pressure, insulin resistance, and atherogenic dyslipidemia. Methods: We studied a population-based samp...
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