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Bhim M. Adhikari
University of Maryland, Baltimore
PsychologyNeuroscienceFunctional magnetic resonance imagingResting state fMRISchizophrenia
36Publications
13H-index
386Citations
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Publications 41
Newest
#1Stephanie M. HareH-Index: 3
#2Bhim M. AdhikariH-Index: 13
Last. Elliot HongH-Index: 7
view all 6 authors...
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#1Bhim M. AdhikariH-Index: 13
#2L. Elliot HongH-Index: 35
Last. Peter KochunovH-Index: 24
view all 10 authors...
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#1Stephanie M. Hare (UMB: University of Maryland, Baltimore)H-Index: 3
#2Joshua ChiappelliH-Index: 16
Last. Laura M. RowlandH-Index: 25
view all 12 authors...
OBJECTIVE: Schizophrenia is associated with excess medical mortality: patients have an average life expectancy one to two decades shorter than the general population. This study investigates the relationship between aberrant hippocampal resting-state functional connectivity in schizophrenia and cumulative subclinical effects of chronic stress on metabolic, cardiovascular and immune function using the allostatic load index. METHODS: Cumulative stress was estimated using allostatic load total scor...
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#1Paul M. Thompson (SC: University of Southern California)H-Index: 141
#2Neda Jahanshad (SC: University of Southern California)H-Index: 42
Last. Willem Bruin (UvA: University of Amsterdam)H-Index: 1
view all 170 authors...
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in ...
9 CitationsSource
#1Bhim M. Adhikari (UMB: University of Maryland, Baltimore)H-Index: 13
#2Jürgen Dukart (HHU: University of Düsseldorf)H-Index: 20
Last. Peter Kochunov (UMB: University of Maryland, Baltimore)H-Index: 24
view all 13 authors...
Subanesthetic administration of ketamine is a pharmacological model to elicit positive and negative symptoms of psychosis in healthy volunteers. We used resting-state pharmacological functional MRI (rsPhfMRI) to identify cerebral networks affected by ketamine and compared them to the functional connectivity (FC) in schizophrenia. Ketamine can produce sedation and we contrasted its effects with the effects of the anxiolytic drug midazolam. Thirty healthy male volunteers (age = 19-37 years) underw...
1 CitationsSource
#1Peter KochunovH-Index: 24
#2Junchao HuangH-Index: 1
Last. L. Elliot HongH-Index: 35
view all 23 authors...
Objective:Failure of antipsychotic medications to resolve symptoms in patients with schizophrenia creates a clinical challenge that is known as treatment resistance. The causes of treatment resista...
1 CitationsSource
#1Bhim M. Adhikari (UMB: University of Maryland, Baltimore)H-Index: 13
#2Neda Jahanshad (SC: University of Southern California)H-Index: 42
Last. Peter Kochunov (UMB: University of Maryland, Baltimore)H-Index: 24
view all 33 authors...
Large-scale consortium efforts such as Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) and other collaborative efforts show that combining statistical data from multiple independent studies can boost statistical power and achieve more accurate estimates of effect sizes, contributing to more reliable and reproducible research. A meta- analysis would pool effects from studies conducted in a similar manner, yet to date, no such harmonized protocol exists for resting state fMRI (rsfMR...
4 CitationsSource
#1Bhim M. Adhikari (UMB: University of Maryland, Baltimore)H-Index: 13
#2L. Elliot Hong (UMB: University of Maryland, Baltimore)H-Index: 35
Last. Peter Kochunov (UMB: University of Maryland, Baltimore)H-Index: 24
view all 11 authors...
1 CitationsSource
#1Bhim M. AdhikariH-Index: 13
#2L. Elliot HongH-Index: 35
Last. Peter KochunovH-Index: 24
view all 11 authors...
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