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Alexander Kokkinos
National and Kapodistrian University of Athens
47Publications
15H-index
1,162Citations
Publications 47
Newest
#1Nikolaos Perakakis (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 9
#2Alexander Kokkinos (UoA: National and Kapodistrian University of Athens)H-Index: 15
Last.Christos S. Mantzoros (Harvard University)H-Index: 106
view all 9 authors...
Abstract Aims Bariatric surgery leads to profound and sustainable weight loss. Gastrointestinal hormones are involved in energy and glucose homeostasis, thus postoperative changes of their circulating levels may be mediating future weight loss. To investigate how the circulating concentrations of gastrointestinal hormones change in response to the most common types of bariatric operation and whether these changes can predict future weight loss. Materials and Methods We measured circulating GLP-1...
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#1Alexander Kokkinos (UoA: National and Kapodistrian University of Athens)H-Index: 15
#2Dimitrios Tsilingiris (UoA: National and Kapodistrian University of Athens)H-Index: 1
Last.Christos S. Mantzoros (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 106
view all 5 authors...
Abstract Bariatric surgery is currently the most effective therapeutic modality through which sustained beneficial effects on weight loss and metabolic improvement are achieved. During recent years, indications for bariatric surgery have been expanded to include cases of poorly controlled type 2 (T2DM) diabetes mellitus in lesser extremes of body weight. A spectrum of the beneficial effects of surgery is attributed to robust changes of postprandial gut peptide responses that are observed post op...
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#1Chrysi Koliaki (UoA: National and Kapodistrian University of Athens)H-Index: 3
#2Stavros Liatis (UoA: National and Kapodistrian University of Athens)H-Index: 10
Last.Alexander Kokkinos (UoA: National and Kapodistrian University of Athens)H-Index: 15
view all 4 authors...
This review provides a comprehensive update on the definition, assessment, epidemiology, pathophysiology, clinical implications, and therapeutic approach of sarcopenic obesity (SO) and highlights the challenges, limitations, and knowledge gaps in SO research. The confluence of a rapidly aging population with rising obesity rates has led to the phenotype of SO, defined as the concurrent presence of sarcopenia and obesity. Despite efforts, a standardized definition of SO is still lacking. Its prev...
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#1Georgia Argyrakopoulou (UoA: National and Kapodistrian University of Athens)H-Index: 4
#2Paraskevi Kontrafouri (UoA: National and Kapodistrian University of Athens)
Last.Nicholas Tentolouris (UoA: National and Kapodistrian University of Athens)H-Index: 9
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Objective The aim of our study was to investigate the potential differential effect of hyperglycaemia and hyperinsulinaemia induced by glucose infusion alone and in combination with leucine consumption on endothelial function in healthy individuals. Methods Ten male volunteers were examined in random order twice. In one visit, they consumed 250 ml water (baseline) and 30 min later glucose was infused iv. In the other visit, they consumed 250 ml water with 25 g of leucine and 30 min later the sam...
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#1Panagiota BinouH-Index: 1
#2Amalia E. YanniH-Index: 6
Last.Alexander KokkinosH-Index: 15
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Although type 2 diabetes mellitus (T2DM) has been traditionally viewed as an intractable chronic medical condition, accumulating evidence points towards the notion that a complete remission of T2DM is feasible following a choice of medical and/or surgical interventions. This has been paralleled by increasing interest in the establishment of a universal definition for T2DM remission which, under given circumstances, could be considered equivalent to a “cure”. The efficacy of bariatric surgery in ...
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#1I. P. Kalafati (UoA: National and Kapodistrian University of Athens)H-Index: 1
#2Maria Dimitriou (UoA: National and Kapodistrian University of Athens)H-Index: 5
Last.George Dedoussis (UoA: National and Kapodistrian University of Athens)H-Index: 63
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Purpose Non-alcoholic fatty liver disease (NAFLD) is a complex disease, resulting from a variety of genetic and environmental factors. The aim of this case–control study was to evaluate the effect of selected genetic polymorphisms, nutrition aspects and their interaction on the risk of NAFLD.
1 CitationsSource
#1Ioanna-Panagiota Kalafati (UoA: National and Kapodistrian University of Athens)H-Index: 1
#2Dimitra Borsa (UoA: National and Kapodistrian University of Athens)H-Index: 1
Last.George Vassilios Dedoussis (UoA: National and Kapodistrian University of Athens)H-Index: 1
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Abstract Objective The aim of this study was to test the hypothesis that posteriori-derived dietary patterns of a Greek sample are associated with the odds for non-alcoholic fatty liver disease (NAFLD) and common NAFLD-related biomarkers. Methods We recruited 351 individuals (134 NAFLD patients, 217 controls). NAFLD was diagnosed with abdominal ultrasound. Dietary intake data were collected through a semi-quantitative food frequency questionnaire of 172 items and dietary patterns were derived by...
2 CitationsSource
#1Eleni Asprouli (UoA: National and Kapodistrian University of Athens)H-Index: 1
#2Ioanna Panagiota Kalafati (UoA: National and Kapodistrian University of Athens)H-Index: 1
Last.Nick Kalogeropoulos (UoA: National and Kapodistrian University of Athens)H-Index: 6
view all 10 authors...
Nonalcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of metabolic syndrome. Its global prevalence is estimated between 25 and 45%, occurring mainly in overweight individuals with unhealthy dietary habits and low levels of physical activity. Many studies have investigated the association of trace elements with liver diseases, though not with NAFLD. In this work, we investigated trace element levels in plasma of patients and not-patients and their possible associatio...
3 CitationsSource
#1Chrysi Koliaki (UoA: National and Kapodistrian University of Athens)H-Index: 3
#2Stavros Liatis (UoA: National and Kapodistrian University of Athens)H-Index: 10
Last.Alexander Kokkinos (UoA: National and Kapodistrian University of Athens)H-Index: 15
view all 3 authors...
Abstract A wealth of clinical and epidemiological evidence has linked obesity to a broad spectrum of cardiovascular diseases (CVD) including coronary heart disease, heart failure, hypertension, stroke, atrial fibrillation and sudden cardiac death. Obesity can increase CVD morbidity and mortality directly and indirectly. Direct effects are mediated by obesity-induced structural and functional adaptations of the cardiovascular system to accommodate excess body weight, as well as by adipokine effec...
16 CitationsSource
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