Thomas R. Gildea
Cleveland Clinic
RadiologySurgeryIntensive care medicineBronchoscopyMedicine
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Publications 187
#1Lucas Upperman (Cleveland Clinic)
#2Thomas R. Gildea (Cleveland Clinic)H-Index: 21
Last. Ursula Galway (Cleveland Clinic)H-Index: 3
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Transnasal humidified rapid insufflation ventilatory exchange (THRIVE) has been shown to prevent desaturation and prolong apnoeic time in the perioperative setting. Previously, pulmonary hypertension was not studied using this technique, due to concern for hypercapnia and resultant transient worsening of mean pulmonary artery pressure. We describe a patient with severe pulmonary hypertension (mean pulmonary artery pressure of 82 mmHg) who underwent bronchoscopy using deep sedation with THRIVE. T...
#1Atul C. Mehta Mbbs (Cleveland Clinic)H-Index: 53
#1Atul C. Mehta (Cleveland Clinic)H-Index: 53
Last. Thomas R. Gildea (Cleveland Clinic)H-Index: 21
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Bronchoscopy is essential to the practice of pulmonary medicine. It is an important diagnostic and therapeutic tool for many disease processes. Bronchoscopy can be performed in a variety of clinical settings, from the bedside to an operating room. Although bronchoscopy has been practiced for more than a century, consensus recommendations from stakeholders have yet to be developed for the planning, implementation, and construction of a bronchoscopy suite. A wide range of procedures can be perform...
#1Gabriela Martinez-Zayas (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 1
#2Francisco A. Almeida (Cleveland Clinic)H-Index: 12
Last. David Ost (University of Texas MD Anderson Cancer Center)H-Index: 30
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Rationale: When stereotactic ablative radiotherapy (SABR) is an option for non-small cell lung cancer (NSCLC) patients, distinguishing between N0, N1 and N2 or N3 (N2|3) disease is important. Objec...
1 CitationsSource
#1Alexander ChenH-Index: 10
#2Nicholas J. PastisH-Index: 13
Last. Gerard A. SilvestriH-Index: 50
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#1Priyanka Gopal (Case Western Reserve University)H-Index: 2
#2Elif I. Sarihan (Cleveland Clinic)
Last. Mohamed E. Abazeed (Cleveland Clinic)H-Index: 6
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Molecular determinants governing the evolution of tumor subclones toward phylogenetic branches or fixation remain unknown. Using sequencing data, we model the propagation and selection of clones expressing distinct categories of BRAF mutations to estimate their evolutionary trajectories. We show that strongly activating BRAF mutations demonstrate hard sweep dynamics, whereas mutations with less pronounced activation of the BRAF signaling pathway confer soft sweeps or are subclonal. We use clonal...
1 CitationsSource
#1Carlos A. LeonH-Index: 6
#2Hanine InatyH-Index: 2
Last. Thomas R. GildeaH-Index: 21
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#1Thomas R. GildeaH-Index: 21
#2Erik FolchH-Index: 17
Last. Jennifer MattingleyH-Index: 2
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