Rita Wegmüller
ETH Zurich
Publications 51
#1Rita WegmüllerH-Index: 20
#2Helena J Bentil (University of Ghana)H-Index: 1
Last.Esi Foriwa AmoafulH-Index: 2
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Nationally representative data on the micronutrient status of Ghanaian women and children are very scarce. We aimed to document the current national prevalence of micronutrient deficiencies, anemia, malaria, inflammation, α-thalassemia, sickle cell disease and trait, and under- and over-nutrition in Ghana. In 2017, a two-stage cross-sectional design was applied to enroll pre-school children (6–59 months) and non-pregnant women (15–49 years) from three strata in Ghana: Northern, Middle and Southe...
#1Sarah J Zyba (UC Davis: University of California, Davis)
#2Rita Wegmüller (ETH Zurich)H-Index: 20
Last.K. Ryan Wessells (UC Davis: University of California, Davis)H-Index: 12
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#1Sarah Prentice (Lond: University of London)H-Index: 3
#2Amadou T. Jallow (Lond: University of London)H-Index: 2
Last.Andrew M. Prentice (Lond: University of London)H-Index: 88
view all 9 authors...
Septicemia is a leading cause of death among neonates in low-income settings, a situation that is deteriorating due to high levels of antimicrobial resistance. Novel interventions are urgently needed. Iron stimulates the growth of most bacteria and hypoferremia induced by the acute phase response is a key element of innate immunity. Cord blood, which has high levels of hemoglobin, iron and transferrin saturation, has hitherto been used as a proxy for the iron status of neonates. We investigated ...
1 CitationsSource
#1Amat Bah (Lond: University of London)H-Index: 4
#2Amat Bah (Lond: University of London)H-Index: 1
Last.Andrew M. Prentice (Lond: University of London)H-Index: 88
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Summary Background WHO recommends daily iron supplementation for pregnant women, but adherence is poor because of side-effects, effectiveness is low, and there are concerns about possible harm. The iron-regulatory hormone hepcidin can signal when an individual is ready-and-safe to receive iron. We tested whether a hepcidin-guided screen-and-treat approach to combat iron-deficiency anaemia could achieve equivalent efficacy to universal administration, but with lower exposure to iron. Methods We d...
1 CitationsSource
#1Nicolai PetryH-Index: 13
#2Bakary JallowH-Index: 1
Last.James P. WirthH-Index: 7
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Data on micronutrient deficiency prevalence, nutrition status, and risk factors of anemia in The Gambia is scanty. To fill this data gap, a nationally representative cross-sectional survey was conducted on 1354 children (0–59 months), 1703 non-pregnant women (NPW; 15–49 years), and 158 pregnant women (PW). The survey assessed the prevalence of under and overnutrition, anemia, iron deficiency (ID), iron deficiency anemia (IDA), vitamin A deficiency (VAD), and urinary iodine concentration (UIC). M...
1 CitationsSource
#1Crystal D. Karakochuk (UBC: University of British Columbia)H-Index: 9
#2Sonja Y. Hess (UC Davis: University of California, Davis)H-Index: 27
Last.Omar Dary (United States Agency for International Development)H-Index: 7
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#1Coralie Signorell (ETH Zurich)H-Index: 1
#2Michael B. Zimmermann (ETH Zurich)H-Index: 64
Last.Diego Moretti (ETH Zurich)H-Index: 18
view all 11 authors...
#1Morgan M. Goheen (UNC: University of North Carolina at Chapel Hill)H-Index: 7
#2Amat BahH-Index: 4
Last.Carla CeramiH-Index: 16
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Anaemia and malaria are both common in pregnant women in Sub-Saharan Africa. Previous evidence has shown that iron supplementation may increase malaria risk. In this observational cohort study, we evaluated P. falciparum pathogenesis in vitro in RBCs from pregnant women during their 2nd and 3rd trimesters. RBCs were collected and assayed before (n = 327), 14 days (n = 82), 49 days (n = 112) and 84 days (n = 115) after iron supplementation (60 mg iron as ferrous fumarate daily). P. falciparum ery...
4 CitationsSource
#1Kamilla G. Eriksen (Medical Research Council)H-Index: 3
#2Elizabeth J. Radford (University of Cambridge)H-Index: 12
Last.Andrew M. Prentice (Medical Research Council)H-Index: 88
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The prenatal environment can alter an individual’s developmental trajectory with long-lasting effects on health. Animal models demonstrate that the impact of the early life environment extends to s...
1 CitationsSource
#1Dominik GlinzH-Index: 11
#2Rita WegmüllerH-Index: 20
Last.Richard F. HurrellH-Index: 66
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Iron deficiency anemia (IDA) is a major public health problem in sub-Saharan Africa. The efficacy of iron fortification against IDA is uncertain in malaria-endemic settings. The objective of this study was to evaluate the efficacy of a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP) to combat IDA in preschool-age children in a highly malaria endemic region. This is a secondary analysis of a nine-month cluster-...
7 CitationsSource