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Erik Kaestner
University of California, San Diego
PsychologyNeuroscienceCognitive psychologyElectrocorticographyTemporal lobe
14Publications
5H-index
178Citations
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Publications 16
Newest
#1Erik Kaestner (UCSD: University of California, San Diego)H-Index: 5
#2Akshara R. Balachandra (UCSD: University of California, San Diego)H-Index: 3
Last. Carrie R. McDonald (UCSD: University of California, San Diego)H-Index: 29
view all 11 authors...
ABSTRACT Objective The distributed white matter network underlying language leads to difficulties in extracting clinically meaningful summaries of neural alterations leading to language impairment. Here we determine the predictive ability of the structural connectome (SC), compared with global measures of white matter tract microstructure and clinical data, to discriminate language impaired patients with temporal lobe epilepsy (TLE) from TLE patients without language impairment. Methods T1- and ...
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#1Anny Reyes (UCSD: University of California, San Diego)H-Index: 4
#2Sanam J. Lalani (UCSF: University of California, San Francisco)
Last. Carrie R. McDonald (UCSD: University of California, San Diego)H-Index: 29
view all 9 authors...
Abstract Cerebrovascular risk factors (CVRFs) and comorbid cardiovascular and metabolic disease have been linked to accelerated cognitive aging and dementia in the general population; however, the contribution of these comorbidities to the risk of post anterior temporal lobectomy (ATL) memory decline has been unexamined. We explored the effects of CVRFs on postoperative verbal memory decline in a cohort of 22 patients with left temporal lobe epilepsy (LTLE) who completed pre- and one-year postsu...
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#1Erik Kaestner (UCSD: University of California, San Diego)H-Index: 5
#2Anny Reyes (UCSD: University of California, San Diego)H-Index: 4
Last. Carrie R. McDonald (UCSD: University of California, San Diego)H-Index: 29
view all 7 authors...
1 CitationsSource
#1Anny ReyesH-Index: 4
#2Erik KaestnerH-Index: 5
Last. Carrie R. McDonaldH-Index: 29
view all 8 authors...
Objective To identify distinct cognitive phenotypes in temporal lobe epilepsy (TLE) and evaluate patterns of white matter (WM) network alterations associated with each phenotype. Methods Seventy patients with TLE were characterized into 4 distinct cognitive phenotypes based on patterns of impairment in language and verbal memory measures (language and memory impaired, memory impaired only, language impaired only, no impairment). Diffusion tensor imaging was obtained in all patients and in 46 hea...
3 CitationsSource
#1Nicholas Rogers (UCSD: University of California, San Diego)H-Index: 1
#2John Hermiz (UCSD: University of California, San Diego)H-Index: 3
Last. Vikash Gilja (UCSD: University of California, San Diego)H-Index: 24
view all 14 authors...
Electrocorticography (ECoG) is becoming more prevalent due to improvements in fabrication and recording technology as well as its ease of implantation compared to intracortical electrophysiology, larger cortical coverage, and potential advantages for use in long term chronic implantation. Given the flexibility in the design of ECoG grids, which is only increasing, it remains an open question what geometry of the electrodes is optimal for an application. Conductive polymer, PEDOT:PSS, coated micr...
1 CitationsSource
#1John Hermiz (UCSD: University of California, San Diego)H-Index: 3
#2Nicholas Rogers (UCSD: University of California, San Diego)H-Index: 1
Last. Vikash Gilja (UCSD: University of California, San Diego)H-Index: 24
view all 10 authors...
Abstract Electrocorticography (ECoG), electrophysiological recording from the pial surface of the brain, is a critical measurement technique for clinical neurophysiology, basic neurophysiology studies, and demonstrates great promise for the development of neural prosthetic devices for assistive applications and the treatment of neurological disorders. Recent advances in device engineering are poised to enable orders of magnitude increase in the resolution of ECoG without comprised measurement qu...
4 CitationsSource
#1Erik Kaestner (UCSD: University of California, San Diego)H-Index: 5
#2Adam Milton Morgan (UCSD: University of California, San Diego)H-Index: 4
Last. Eric Halgren (UCSD: University of California, San Diego)H-Index: 70
view all 9 authors...
ABSTRACTIntracranial electrophysiology (iEEG) studies using cognitive tasks contribute to the understanding of the neural basis of language. However, though iEEG is recorded continuously during clinical treatment, due to patient considerations task time is limited. To increase the usefulness of iEEG recordings for language study we provided patients with a tablet pre-loaded with media filled with natural language, wirelessly synchronised to clinical iEEG. This iEEG data collected and time-locked...
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#1Mehran Ganji (UCSD: University of California, San Diego)H-Index: 4
#2Erik Kaestner (UCSD: University of California, San Diego)H-Index: 5
Last. Shadi A. Dayeh (UCSD: University of California, San Diego)H-Index: 32
view all 18 authors...
Recording neural activity during neurosurgical interventions is an invaluable tool for both improving patient outcomes and advancing our understanding of neural mechanisms and organization. However, increasing clinical electrodes' signal-to-noise and spatial specificity requires overcoming substantial physical barriers due to the compromised metal electrochemical interface properties. The electrochemical properties of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) based inte...
16 CitationsSource
#1Erik KaestnerH-Index: 5
Author(s): Kaestner, Erik | Advisor(s): Halgren, Eric | Abstract: Reading is learned in the presence of an already formed auditory language network. However, unlike auditory language reading is a recent cultural invention made possible by an extensive period of learning. Understanding the relationship of visual language with auditory language is key to understanding the novel human construct of reading. Articulatory motor movements are a potential bridge between the existing auditory language ne...
1 Citations
Aug 1, 2016 in EMBC (International Conference of the IEEE Engineering in Medicine and Biology Society)
#1John Hermiz (UCSD: University of California, San Diego)H-Index: 3
#2Nick Rogers (UCSD: University of California, San Diego)H-Index: 3
Last. Vikash Gilja (UCSD: University of California, San Diego)H-Index: 24
view all 10 authors...
Open source electrophysiology (ephys) recording systems have several advantages over commercial systems such as customization and affordability enabling more researchers to conduct ephys experiments. Notable open source ephys systems include Open-Ephys, NeuroRighter and more recently Willow, all of which have high channel count (64+), scalability, and advanced software to develop on top of. However, little work has been done to build an open source ephys system that is clinic compatible, particu...
4 CitationsSource
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