Dariush Mozaffarian
Tufts University
Publications 692
Optimal metrics to assess healthfulness of carbohydrate-rich products are not well established. We investigated how the content per 10 g of carbohydrate of at least 1 g of fiber (≤ 10:1-ratio) related to nutritional quality in grain foods as well as cardiometabolic risk factors in Sao Paulo, Brazil. Data were from the cross-sectional population-based study 2015 Health Survey of Sao Paulo, including a probabilistic sample of urban residents in the city. Participants (n = 1188) aged 20 + years com...
Background Poor diet is a leading risk factor for cardiometabolic disease (CMD) in the United States, but its economic costs are unknown. We sought to estimate the cost associated with suboptimal diet in the US. Methods and findings A validated microsimulation model (Cardiovascular Disease Policy Model for Risk, Events, Detection, Interventions, Costs, and Trends [CVD PREDICT]) was used to estimate annual cardiovascular disease (fatal and nonfatal myocardial infarction, angina, and stroke) and t...
In 2010, sugar sweetened beverages (SSBs) were estimated to cause 12% of all diabetes, cardiovascular disease (CVD) and obesity-related cancer deaths in Mexico. Using new risk estimates for SSBs consumption, we aimed to update the fraction of Mexican mortality attributable to SSBs, and provide subnational estimates by region, age, and sex. We used an established comparative risk assessment framework. All-cause mortality estimates were calculated from a recent pooled cohort analysis. Age- and sex...
Background Synthesized fatty acids (FAs) from de novo lipogenesis may affect cardiometabolic health, but longitudinal associations between serially measured de novo lipogenesis–related fatty acid b...
#1Gitanjali M. Singh (Tufts University)H-Index: 55
#2Ninon A. Becquart (Tufts University)H-Index: 1
Last.Elena N. Naumova (Tufts University)H-Index: 37
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Background The US population is aging, with concurrent increases in cardiovascular disease (CVD) burdens; however, spatiotemporal and demographic trends in CVD incidence in the US elderly have not ...
#1David D. Kim (Tufts Medical Center)H-Index: 11
#2Parke Wilde (Tufts University)H-Index: 24
Last.John B. Wong (Tufts Medical Center)H-Index: 110
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Introduction Processed meats are associated with increased risk of colorectal and stomach cancers, but health and economic impacts of policies to discourage processed meats are not well established. This paper aims to evaluate the cost effectiveness of implementing tax and warning labels on processed meats. Methods A probabilistic cohort-state transition model was developed in 2018, including lifetime and short-term horizons, healthcare, and societal perspectives, and 3% discount rates for costs...
#1Andres V. Ardisson Korat (Harvard University)H-Index: 5
#2Vasanti S. Malik (Harvard University)H-Index: 36
Last.Qi Sun (Harvard University)H-Index: 62
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#1Jason H.Y. Wu (The George Institute for Global Health)H-Index: 35
#2Renata Micha (Tufts University)H-Index: 40
Last.Dariush Mozaffarian (Tufts University)H-Index: 120
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The effect of dietary fats on cardiometabolic diseases, including cardiovascular diseases and type 2 diabetes mellitus, has generated tremendous interest. Many earlier investigations focused on total fat and conventional fat classes (such as saturated and unsaturated fats) and their influence on a limited number of risk factors. However, dietary fats comprise heterogeneous molecules with diverse structures, and growing research in the past two decades supports correspondingly complex health effe...
1 CitationsSource
#1Zhilei Shan (HUST: Huazhong University of Science and Technology)H-Index: 13
#2Colin D. Rehm (Albert Einstein College of Medicine)H-Index: 28
Last.Shilpa N. Bhupathiraju (Harvard University)H-Index: 24
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Importance Changes in the economy, nutrition policies, and food processing methods can affect dietary macronutrient intake and diet quality. It is essential to evaluate trends in dietary intake, food sources, and diet quality to inform policy makers. Objective To investigate trends in dietary macronutrient intake, food sources, and diet quality among US adults. Design, Setting, and Participants Serial cross-sectional analysis of the US nationally representative 24-hour dietary recall data from 9...