Match!
James C.H. Goh
National University of Singapore
201Publications
51H-index
7,527Citations
Publications 198
Newest
#1Miss Ling Liu (NUS: National University of Singapore)
#2LamWing Moon Raymond (NUS: National University of Singapore)H-Index: 2
Last.Hee-Kit Wong (NUS: National University of Singapore)H-Index: 22
view all 11 authors...
BMP-2 is widely used in spinal fusion but can cause adverse effects like the formation of ectopic bone and adipose tissue in vivo. Nel-like molecule-1 (NELL-1) has been shown to suppress BMP-2-indu...
Source
#1Lynn Yap (Agency for Science, Technology and Research)H-Index: 2
#2Sadasivam Murali (Agency for Science, Technology and Research)H-Index: 13
Last.Simon M. Cool (Agency for Science, Technology and Research)H-Index: 41
view all 18 authors...
Functionalizing medical devices with polypeptides to enhance their performance has become important for improved clinical success. The extracellular matrix (ECM) adhesion protein vitronectin (VN) is an effective coating, although the chemistry used to attach VN often reduces its bioactivity. In vivo, VN binds the ECM in a sequence-dependent manner with heparan sulfate (HS) glycosaminoglycans. We reasoned therefore that sequence-based affinity chromatography could be used to isolate a VN-binding ...
2 CitationsSource
#1Gajadhar Bhakta (Agency for Science, Technology and Research)H-Index: 10
#2Andrew K. Ekaputra (Agency for Science, Technology and Research)H-Index: 1
Last.Simon M. Cool (Agency for Science, Technology and Research)H-Index: 41
view all 19 authors...
Abstract Background Context Interbody spinal fusion relies on the use of external fixation and the placement of a fusion cage filled with graft materials (scaffolds) without regard for their mechanical performance. Stability at the fusion site is instead reliant on fixation hardware combined with a selected cage. Ideally, scaffolds placed into the cage should both support the formation of new bone and contribute to the mechanical stability at the fusion site. Purpose We recently developed a scaf...
4 CitationsSource
#1Hossein Mokhtarzadeh (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 5
#2Chen-Hua Yeow (NUS: National University of Singapore)H-Index: 17
Last.Peter Vee Sin Lee (University of Melbourne)H-Index: 19
view all 6 authors...
Background: Knee injuries are common during landing activities. Greater landing height increases peak ground reaction forces (GRFs) and loading at the knee joint. As major muscles to stabilize the knee joint, Quadriceps and Hamstring muscles provide internal forces to attenuate the excessive GRF. Despite the number of investigations on the importance of muscle function during landing, the role of landing height on these muscles forces using modeling during landing is not fully investigated. Meth...
1 CitationsSource
#1Ngoc-Duy Dinh (NUS: National University of Singapore)H-Index: 3
#2Rongcong Luo (NUS: National University of Singapore)H-Index: 10
Last.Chia-Hung Chen (NUS: National University of Singapore)H-Index: 19
view all 7 authors...
Light-directed forces have been widely used to pattern micro/nanoscale objects with precise control, forming functional assemblies. However, a substantial laser intensity is required to generate sufficient optical gradient forces to move a small object in a certain direction, causing limited throughput for applications. A high-throughput light-directed assembly is demonstrated as a printing technology by introducing gold nanorods to induce thermal convection flows that move microparticles (diame...
1 CitationsSource
#1Liang Zhang (NUS: National University of Singapore)H-Index: 4
#2Sri Gowtham ThakkuH-Index: 6
Last.Michaël J. A. Girard (NUS: National University of Singapore)H-Index: 25
view all 8 authors...
We aimed to verify a custom virtual fields method (VFM) to estimate the patient-specific biomechanical properties of human optic nerve head (ONH) tissues, given their full-field deformations induced by intraocular pressure (IOP). To verify the accuracy of VFM, we first generated ‘artificial’ ONH displacements from predetermined (known) ONH tissue biomechanical properties using finite element analysis. Using such deformations, if we are able to match back the known biomechanical properties, it wo...
14 CitationsSource
#1Hong Kai Yap (NUS: National University of Singapore)H-Index: 10
#2Nazir Kamaldin (NUS: National University of Singapore)H-Index: 4
Last.Chen-Hua Yeow (NUS: National University of Singapore)H-Index: 17
view all 6 authors...
In this paper, we present the design, fabrication and evaluation of a soft wearable robotic glove, which can be used with functional Magnetic Resonance imaging (fMRI) during the hand rehabilitation and task specific training. The soft wearable robotic glove, called MR-Glove, consists of two major components: a) a set of soft pneumatic actuators and b) a glove. The soft pneumatic actuators, which are made of silicone elastomers, generate bending motion and actuate finger joints upon pressurizatio...
29 CitationsSource
#1Ngoc-Duy Dinh (NUS: National University of Singapore)H-Index: 3
#2Rongcong Luo (NUS: National University of Singapore)H-Index: 10
Last.Chia-Hung Chen (NUS: National University of Singapore)H-Index: 19
view all 7 authors...
Source
#1James C.H. Goh (NUS: National University of Singapore)H-Index: 51
Source
#1T.K.H. Teh (NUS: National University of Singapore)
#2James C.H. Goh (NUS: National University of Singapore)H-Index: 51
Ligament tissue engineering has achieved much progress in recent years and many potential tissue-engineered ligaments used for ligament regeneration have been reported. The success of ligament regeneration procedure depends on three major factors: implant characteristics (including scaffolds, cells, and signaling molecules), surgical procedure, and postsurgery rehabilitation. The major challenges include complex mechanical stress faced by tissue-engineered anterior cruciate ligament (ACL), harsh...
Source
12345678910