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James Cho Hong Goh
National University of Singapore
197Publications
49H-index
7,229Citations
Publications 197
Newest
Published on Jul 24, 2019in Tissue Engineering Part A
Ling Liu (NUS: National University of Singapore), LamWing Moon Raymond2
Estimated H-index: 2
(NUS: National University of Singapore)
+ 8 AuthorsJames Cho Hong Goh49
Estimated H-index: 49
(NUS: National University of Singapore)
Published on Jul 1, 2018in Journal of Biomedical Materials Research Part B2.67
Lynn Yap2
Estimated H-index: 2
(Agency for Science, Technology and Research),
Sadasivam Murali12
Estimated H-index: 12
(Agency for Science, Technology and Research)
+ 15 AuthorsSteve Oh35
Estimated H-index: 35
(Agency for Science, Technology and Research)
Functionalizing medical devices with polypeptides to enhance their performance has become important for improved clinical success. The extracellular matrix (ECM) adhesion protein vitronectin (VN) is an effective coating, although the chemistry used to attach VN often reduces its bioactivity. In vivo, VN binds the ECM in a sequence-dependent manner with heparan sulfate (HS) glycosaminoglycans. We reasoned therefore that sequence-based affinity chromatography could be used to isolate a VN-binding ...
Published on Dec 1, 2017in The Spine Journal3.20
Gajadhar Bhakta9
Estimated H-index: 9
(Agency for Science, Technology and Research),
Andrew K. Ekaputra11
Estimated H-index: 11
(Agency for Science, Technology and Research)
+ 16 AuthorsM. Tarik Arafat5
Estimated H-index: 5
(NUS: National University of Singapore)
Abstract Background Context Interbody spinal fusion relies on the use of external fixation and the placement of a fusion cage filled with graft materials (scaffolds) without regard for their mechanical performance. Stability at the fusion site is instead reliant on fixation hardware combined with a selected cage. Ideally, scaffolds placed into the cage should both support the formation of new bone and contribute to the mechanical stability at the fusion site. Purpose We recently developed a scaf...
Hossein Mokhtarzadeh4
Estimated H-index: 4
(BIDMC: Beth Israel Deaconess Medical Center),
Chen-Hua Yeow15
Estimated H-index: 15
(NUS: National University of Singapore)
+ 3 AuthorsPeter Vee Sin Lee18
Estimated H-index: 18
(University of Melbourne)
Background: Knee injuries are common during landing activities. Greater landing height increases peak ground reaction forces (GRFs) and loading at the knee joint. As major muscles to stabilize the knee joint, Quadriceps and Hamstring muscles provide internal forces to attenuate the excessive GRF. Despite the number of investigations on the importance of muscle function during landing, the role of landing height on these muscles forces using modeling during landing is not fully investigated. Meth...
Published on Jun 1, 2017in Small10.86
Ngoc-Duy Dinh3
Estimated H-index: 3
(NUS: National University of Singapore),
Rongcong Luo10
Estimated H-index: 10
(NUS: National University of Singapore)
+ 4 AuthorsChia-Hung Chen18
Estimated H-index: 18
(NUS: National University of Singapore)
Light-directed forces have been widely used to pattern micro/nanoscale objects with precise control, forming functional assemblies. However, a substantial laser intensity is required to generate sufficient optical gradient forces to move a small object in a certain direction, causing limited throughput for applications. A high-throughput light-directed assembly is demonstrated as a printing technology by introducing gold nanorods to induce thermal convection flows that move microparticles (diame...
Published on Jun 1, 2017in Biomechanics and Modeling in Mechanobiology2.83
Liang Zhang3
Estimated H-index: 3
(NUS: National University of Singapore),
Sri Gowtham Thakku6
Estimated H-index: 6
+ 5 AuthorsMichaël J. A. Girard23
Estimated H-index: 23
(NUS: National University of Singapore)
We aimed to verify a custom virtual fields method (VFM) to estimate the patient-specific biomechanical properties of human optic nerve head (ONH) tissues, given their full-field deformations induced by intraocular pressure (IOP). To verify the accuracy of VFM, we first generated ‘artificial’ ONH displacements from predetermined (known) ONH tissue biomechanical properties using finite element analysis. Using such deformations, if we are able to match back the known biomechanical properties, it wo...
Published on Jun 1, 2017in Small10.86
Ngoc-Duy Dinh3
Estimated H-index: 3
(NUS: National University of Singapore),
Rongcong Luo10
Estimated H-index: 10
(NUS: National University of Singapore)
+ 4 AuthorsChia-Hung Chen18
Estimated H-index: 18
(NUS: National University of Singapore)
Published on Jan 1, 2017
T.K.H. Teh (NUS: National University of Singapore), J.C.H. Goh1
Estimated H-index: 1
(NUS: National University of Singapore)
Ligament tissue engineering has achieved much progress in recent years and many potential tissue-engineered ligaments used for ligament regeneration have been reported. The success of ligament regeneration procedure depends on three major factors: implant characteristics (including scaffolds, cells, and signaling molecules), surgical procedure, and postsurgery rehabilitation. The major challenges include complex mechanical stress faced by tissue-engineered anterior cruciate ligament (ACL), harsh...
Published on Jan 1, 2017in Nanoscale6.97
Pujiang Shi8
Estimated H-index: 8
(Agency for Science, Technology and Research),
Sunny A. Abbah13
Estimated H-index: 13
(NUS: National University of Singapore)
+ 5 AuthorsJames Cho Hong Goh49
Estimated H-index: 49
(NUS: National University of Singapore)
The efficient delivery of bioactive molecules via rationally designed nanoparticles is an important focus in regenerative medicine. The yolk shell nanocomposite particles described herein are composed of silk fibroin movable cores formed within voided calcium carbonate shells to load and control the release of labile cytokines. These particles are excellent carrier vehicles of potent molecules as they sustained the release of bioactive Bone Morphogenetic Protein 2 (BMP-2) for more than 28 days i...
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