Match!
Kottayath Govindan Nevin
University of Kerala
5Publications
3H-index
239Citations
Publications 5
Newest
Gopalakrishnan Salil2
Estimated H-index: 2
,
Kottayath Govindan Nevin3
Estimated H-index: 3
,
Thankappan Rajamohan10
Estimated H-index: 10
(UoK: University of Kerala)
Impaired lipid levels and oxidative stress are indicative of malfunction of endogenous antioxidant capacity. The aim of this study was to determine the effect of coconut kernel protein (CKP) on the lipid peroxides and antioxidant enzyme activities in diabetic rats. Diabetes was induced prior to feeding by injecting a single dose of alloxan (150 mg/kg body weight) intraperitoneally. CKP (8% w/w) was administered to these rats along with a semi-synthetic diet for 45 days. After the experimental pe...
Published on Jul 1, 2012in Journal of the Science of Food and Agriculture2.42
Gopalakrishnan Salil2
Estimated H-index: 2
(UoK: University of Kerala),
Kottayath Govindan Nevin3
Estimated H-index: 3
(UoK: University of Kerala),
Thankappan Rajamohan10
Estimated H-index: 10
(UoK: University of Kerala)
BACKGROUND: Coconut kernel protein (CKP) has been reported to contain significant amounts of L-arginine. Its potential effect on glucose homeostasis, possibly through the nitric oxide synthase (NO) pathway, was therefore investigated in alloxan-induced diabetic rats. Diabetes was induced by a single intraperitoneal dose of alloxan (150 mg kg−1 body weight). Experimental rats were grouped as follows: Group I, normal control; Group II, diabetic control; Group III, diabetic + CKP; Group IV, diabeti...
Gopalakrishnan Salil2
Estimated H-index: 2
(UoK: University of Kerala),
Kottayath Govindan Nevin3
Estimated H-index: 3
(UoK: University of Kerala),
Thankappan Rajamohan10
Estimated H-index: 10
(UoK: University of Kerala)
The objective of this study was to investigate the effect of arginine-rich coconut kernel protein (CKP) on alloxan-induced diabetes in comparison with l-arginine and an antidiabetic drug, glibenclamide. 1-month-old 24 male Sprague–Dawley rats, weighing 130–150 g, were randomly divided into five groups: group I-normal control, group II-diabetic control, group III-diabetic + CKP, group IV-diabetic + l-arginine, group V-diabetic + glibenclamide (0.6 mg/100 g body weight). The rats were induced diab...
Published on Jan 1, 2011in Chemico-Biological Interactions3.41
Gopalakrishnan Salil2
Estimated H-index: 2
(UoK: University of Kerala),
Kottayath Govindan Nevin3
Estimated H-index: 3
(UoK: University of Kerala),
Thankappan Rajamohan10
Estimated H-index: 10
(UoK: University of Kerala)
Abstract Diabetes mellitus is a syndrome characterized by the loss of glucose homeostasis due to several reasons. In spite of the presence of known anti-diabetic medicines in the pharmaceutical market, remedies from natural resources are used with success to treat this disease. The present study was undertaken to investigate the effect of coconut kernel protein (CKP) on alloxan induced diabetes in Sprague–Dawley rats. Diabetes was induced by injecting a single dose of alloxan (150 mg/kg body wei...
1