A. B. Czuppon
Ruhr University Bochum
Publications 31
#1Xaver BaurH-Index: 48
#2Jäger DH-Index: 2
Last.A. B. CzupponH-Index: 16
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6 CitationsSource
#1A. B. Czuppon (RUB: Ruhr University Bochum)H-Index: 16
#2Rolf Merget (RUB: Ruhr University Bochum)H-Index: 24
Last.Thomas Bruening (RUB: Ruhr University Bochum)H-Index: 10
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Background: Acid anhydrides are used in a variety of industrial branches because of their highly reactive anhydride groups. Adverse effects of anhydride exposure include toxic/irrit
2 CitationsSource
12 CitationsSource
#1Xaver BaurH-Index: 48
#2Boleslaw MarczynskiH-Index: 22
Last.A. B. CzupponH-Index: 16
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3 Citations
#1Ingrid Sander (RUB: Ruhr University Bochum)H-Index: 25
#2Monika Raulf-Heimsoth (RUB: Ruhr University Bochum)H-Index: 36
Last.Xaver Baur (RUB: Ruhr University Bochum)H-Index: 48
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Background: To diagnose baker’s asthma, occupational sensitization to wheat flour should be distinguished clearly from influences of cosensitization such as it may exist in pollinos
37 CitationsSource
#1Xaver Baur (RUB: Ruhr University Bochum)H-Index: 48
#2M. Pau (LMU: Ludwig Maximilian University of Munich)H-Index: 1
Last.Günter Fruhmann (LMU: Ludwig Maximilian University of Munich)H-Index: 22
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Fourteen bakers suffering from workplace-related respiratory symptoms and sensitized to soybean were studied. Twelve of them were also allergic to wheat flour, 10 to rye flour, and five to α-amylase of Aspergillus oryzae (Asp o 2). IgE estimation by RAST strongly indicated that the trypsin inhibitor and lipoxidase are major allergens of soybean. Various allergenic components could be characterized by immunoblotting after two-dimensional electrophoresis. Our RAST and immunoblotting results show a...
44 CitationsSource
Abstract Background: The diagnostic possibilities of sensitization to various acid anhydrides are limited because of the lack of standardized allergens for the different test systems. This makes the diagnosis of IgE-mediated sensitization caused by occupational exposure difficult. Methods: We prepared conjugates of human serum albumin with phthalic, maleic, trimellitic, and pyromellitic anhydrides to be used for IgE estimation by enzyme-allergosorbent test, skin prick tests, and nasal and bronch...
38 CitationsSource
This study aimed at investigating sensitizing and hazardous effects of a new acid anhydride, pyromellitic dianhydride (PMDA), in addition to those of phthalic anhydride, maleic anhydride and trimellitic anhydride, in a group of 92 exposed workers in two German chemical plants. Of the 92 workers, 56 reported work-related complaints with a predominance of phlegm and dyspnoea in those exposed to anhydride dust for less than 1 year. Haemorrhagic rhinitis occurred only after a prolonged exposure of m...
31 CitationsSource
#1Xaver Baur (RUB: Ruhr University Bochum)H-Index: 48
#2A. B. Czuppon (RUB: Ruhr University Bochum)H-Index: 16
A 29-year-old female bakery shop assistant was occupationally sensitized to flour allergens and Aspergillus α-amylase (Asp o 2). The latter represents a strongly allergenic component of routinely used baking additives. The patient had repeatedly responded to the consumption of white bread with rhinitis, conjunctivitis, and, occasionally, wheal and flare reactions. She underwent allergologic investigations including oral challenge tests with commercially available bread loaves. Elevated specific ...
35 CitationsSource
#1Xaver Baur (RUB: Ruhr University Bochum)H-Index: 48
#2W. Marek (RUB: Ruhr University Bochum)H-Index: 12
Last.Günter Fruhmann (LMU: Ludwig Maximilian University of Munich)H-Index: 22
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Isocyanates are increasingly being used for manufacturing polyurethane foam, elastomers, adhesives, paints, coatings, insecticides, and many other products. At present, they are regarded as one of the main causes of occupational asthma. The large number of workers who are exposed to these chemicals have a concentration-dependent risk of developing chronic airway disorders, especially bronchial asthma. Different pathophysiologic mechanisms are involved. Immunoglobulin E (IgE)-mediated sensitizati...
141 CitationsSource