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Anil Kumar Bhatta
Tongji University
19Publications
5H-index
92Citations
Publications 19
Newest
#1Jie Ji (Tongji University)H-Index: 5
#2Peiru Wang (Tongji University)H-Index: 6
Last.Xiuli Wang (Tongji University)H-Index: 11
view all 10 authors...
Abstract Background Antitumor immunity induced by photodynamic therapy (PDT) is believed to depend on the degree of local and systemic inflammation. The recruitment of leukocytes, in particular by the chemokine CCL8, to the sites of tissue damage has been strongly associated with the initiation of inflammatory reactions. Objective To evaluate whether and how CCL8 enhances the immune response against tumors in 5-aminolevulinic acid (ALA)-mediated PDT. Methods In this study, we investigated the ef...
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#1Uma Keyal (Tongji University)H-Index: 5
#2Anil Kumar Bhatta (Tongji University)H-Index: 5
Last.Xiu Li Wang (Tongji University)H-Index: 3
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Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer. Surgery remains the main stay of treatment, but some patients are not eligible for surgery and, more importantly, lesions at critical sites need nonsurgical approaches for tissue preservation. In this context, photodynamic therapy (PDT) has been extensively studied as noninvasive or minimally invasive treatment, and studies have shown promising results in terms of safety, efficacy, and cosmetic outcome. Also, studies ...
8 CitationsSource
#1Uma KeyalH-Index: 5
#2Anil Kumar BhattaH-Index: 5
Last.Xiu Li WangH-Index: 3
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#1Uma Keyal (Tongji University)H-Index: 5
#2Anil Kumar Bhatta (Tongji University)H-Index: 5
Last.Yeqiang Liu (Tongji University)H-Index: 2
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#1Uma Keyal (Tongji University)H-Index: 5
#2Qiong LuoH-Index: 1
Last.Lei Shi (Tongji University)H-Index: 7
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4 CitationsSource
#1Anil Kumar Bhatta (Tongji University)H-Index: 5
#2Peiru Wang (Tongji University)H-Index: 6
Last.Guolong Zhang (Tongji University)H-Index: 5
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Abstract Background Topical photodynamic therapy (PDT) is approved treatment for actinic keratosis, basal cell carcinoma and Bowen’s disease. But currently it is not recommended for invasive squamous cell carcinoma (SCC) of the skin because inadequate penetration of topically applied photosensitizers lead to poor treatment response. Imiquimod (IMQ) as an immune response modifier and Toll-like receptor 7 (TLR7) agonist, is known to exhibit antitumor activity. As an adjunct therapy, it is recently...
5 CitationsSource
#1Anil Kumar Bhatta (Tongji University)H-Index: 5
#2Uma Keyal (Tongji University)H-Index: 5
Last.Emese Gellén (University of Debrecen)H-Index: 3
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Source
#1Anil Kumar Bhatta (Tongji University)H-Index: 5
#2Uma Keyal (Tongji University)H-Index: 5
Last.Emese Gellén (University of Debrecen)H-Index: 3
view all 4 authors...
1 CitationsSource
#1Anil Kumar Bhatta (Tongji University)H-Index: 5
#2Yeqiang Liu (Tongji University)H-Index: 2
Last.Uma Keyal (Tongji University)H-Index: 5
view all 3 authors...
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#1Qian Zhou (Tongji University)H-Index: 1
#2Peiru Wang (Tongji University)H-Index: 6
Last.Xiuli Wang (Tongji University)H-Index: 11
view all 9 authors...
Abstract Pemphigus vulgaris (PV) is an autoimmune disorder resulting from the interaction between autoantibodies and desmoglein. Here, we report a case of PV developed after 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT). The harmful and deleterious effects of UV radiation on the onset, during course, and perpetuation of PV have been observed for decades. Correlation between reactive oxygen species (ROS) and PV have also been reported. Oxidative proteins, which are modified by ROS, ...
4 CitationsSource
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