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Didi Rhebergen
VU University Medical Center
Publications 52
Published on May 24, 2019in Translational Psychiatry 5.18
Elisabeth Maria van Zutphen (VUmc: VU University Medical Center), Didi Rhebergen13
Estimated H-index: 13
(VUmc: VU University Medical Center)
+ 6 AuthorsAnnemieke Dols10
Estimated H-index: 10
(VUmc: VU University Medical Center)
While brain-derived neurotrophic factor (BDNF) has been shown to predict response to pharmacotherapy in depression, studies in electroconvulsive therapy (ECT) are small and report conflicting results. This study assesses the association between pre-treatment BDNF levels and ECT outcome in severe late-life unipolar depression (LLD). The potential of BDNF as a clinical predictor of ECT outcome was subsequently evaluated. Characteristics associated with low and high BDNF subgroups were determined a...
Published on Jul 19, 2019in Journal of Affective Disorders 4.08
Ilse P. Dekker (LUMC: Leiden University Medical Center), Radboud M. Marijnissen6
Estimated H-index: 6
(UMCG: University Medical Center Groningen)
+ 4 AuthorsN.R. Ottenheim1
Estimated H-index: 1
(LUMC: Leiden University Medical Center)
Abstract Background : Metabolic syndrome (MetS) has been associated with both early- and late-life depression. This study investigated whether baseline MetS and its individual components are associated with the course of depression over six years among older persons with a formal depression diagnosis. Methods : Data were used from 378 older persons with a depressive disorder from the Netherlands Study of Depression in Old age (NESDO) with a 6-year follow-up. A formal depression diagnosis accordi...
Maarten Laroy (Katholieke Universiteit Leuven), Justien Weydts (Katholieke Universiteit Leuven)+ -3 AuthorsMathieu Vandenbulcke24
Estimated H-index: 24
(Katholieke Universiteit Leuven)
Abstract Accumulating evidence suggests that late-life depression is associated with reduced hippocampal volume and that cortisol might be related to this volumetric reduction. We explored whether cortisol awaking response (CAR), which is the increase in cortisol after awakening, was associated with volumetric changes in the medial temporal lobe (MTL) after electroconvulsive therapy (ECT) in 41 patients (age ≥ 55) treated for major depressive disorder (MDD) with ECT. Cortisol was measured before...
Published on Sep 1, 2019in Drug and Alcohol Dependence 3.47
Marjolein Veerbeek5
Estimated H-index: 5
M. ten Have49
Estimated H-index: 49
+ 3 AuthorsBernadette Willemse11
Estimated H-index: 11
Abstract Background Prevention of problematic alcohol use is mainly focused on younger adults, while heavy drinking in middle-aged and older adults might be more frequent with more impact on functioning and health care use. Therefore, alcohol use and alcohol disorder in both age groups was compared. To facilitate age-specific prevention, it was examined whether risk factors of heavy drinking and impact on functioning and health care use differs across the life-span. Methods Data of people (23-70...
Published on May 1, 2019in Journal of Pain Research 2.24
Tarik T. Binnekade7
Estimated H-index: 7
R.S.G.M. Perez24
Estimated H-index: 24
+ 6 AuthorsF. Lobbezoo16
Estimated H-index: 16
(VU: VU University Amsterdam)
Published on Mar 1, 2019in Journal of Ect 2.28
Eveline Veltman1
Estimated H-index: 1
Alef de Boer + 6 AuthorsDidi Rhebergen13
Estimated H-index: 13
OBJECTIVES: In clinical practice, particularly melancholic depression benefits from electroconvulsive therapy (ECT), albeit research melancholia criteria from the Diagnostic and Statistical Manual of Mental Disorders (DSM) is not conclusive. We compared clinical characteristics and ECT outcome of melancholic and nonmelancholic depression, here defined by psychomotor symptoms. METHODS: One hundred ten depressed older in-patients treated with ECT were included in the Mood Disorders in Elderly trea...
Published on Jan 2, 2019in Aging Clinical and Experimental Research 2.33
Marieke J. Henstra2
Estimated H-index: 2
(UvA: University of Amsterdam),
Didi Rhebergen13
Estimated H-index: 13
+ 7 AuthorsN.M. van Schoor47
Estimated H-index: 47
(VUmc: VU University Medical Center)
Background Symptoms of apathy are common in older persons. Negative effects on physical performance and fall risk are plausible, considering the pathophysiology of apathy. However, literature is scarce.
Published on Dec 10, 2018in International Journal of Geriatric Psychiatry 3.14
Emma J. de Louw (VUmc: VU University Medical Center), Nadine P.G. Paans5
Estimated H-index: 5
+ 9 AuthorsHannie C. Comijs34
Estimated H-index: 34
(VUmc: VU University Medical Center)
Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of...
Published on Oct 1, 2018in Experimental Gerontology 3.08
M.J. Henstra1
Estimated H-index: 1
(PHRI: Public Health Research Institute),
C.M. Houbolt1
Estimated H-index: 1
(PHRI: Public Health Research Institute)
+ 4 AuthorsNathalie van der Velde26
Estimated H-index: 26
(PHRI: Public Health Research Institute)
Apathy, a common and disabling behavioural syndrome in older persons, has been associated with impaired physical performance and executive dysfunction. Both are fall risk factors and they share pathophysiological pathway. We cross-sectionally examined the association between apathy and recurrent falling (≥2 falls in the past 12 months) and number of falls in the past 12 months in 243 outpatients aged ≥65 years with ≥3 fall risk-factors visiting a fall-clinic after a fall. We calculated Odds Rati...