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Nick Hadjiliadis
University of Ioannina
244Publications
36H-index
4,759Citations
Publications 244
Newest
#1C.N. Banti (UoI: University of Ioannina)H-Index: 16
#2Sotiris K. Hadjikakou (UoI: University of Ioannina)H-Index: 34
Last.Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
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Abstract Organotins(IV) exhibit significant in vitro anti-proliferative activity, while the in vivo tests are encouraging. The recent reports on the anti-proliferative activity of organotin(IV) compounds are summarized in this review. The period covered by this work goes back to 2009 until late 2018, while the earlier ones, are included over the previous review of our group published by S.K. Hadjikakou, N. Hadjiliadis, in Coord Chem Rev, 253 (2009) 235–249. During the last decade (2009–2018), >3...
#1Gerasimos Malandrinos (UoI: University of Ioannina)H-Index: 12
#2K. Panagiotou (UoI: University of Ioannina)
Last.Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
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Abstract The interaction of Cu(II) ions with the peptide Ac-GYDVEK-amide (N and C-terminal protected), a well conserved sequence located at N-terminal of the globular domain of somatic histone H1 variants (H1.1–H1.5) was studied by means of potentiometry and spectroscopic techniques. In the absence of a histidine residue, the β-COOH of the aspartic acid becomes the primary binding site. Curiously, this weak binding can prevent Cu(II) precipitation and promote the ionization and coordination of t...
#1Sotiris K. Hadjikakou (UoI: University of Ioannina)H-Index: 34
#2I.I. Ozturk (Namik Kemal University)H-Index: 9
Last.Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
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Abstract Antimony one of the heavier pnictogens, has been in medical use against microbes and parasites as well. Antimony-based drugs have been prescribed against leishmaniasis since the parasitic transmission of the tropical disease was understood in the beginning of the 20th century. The activity of arsenic against visceral leishmaniasis led to the synthesis of an array of arsenic-containing parasitic agents, among them the less toxic pentavalent antimonials: Stibosan, Neostibosan, and Ureasti...
#1C.N. Banti (UoI: University of Ioannina)H-Index: 16
#2D.C. Charalampou (UoI: University of Ioannina)H-Index: 3
Last.Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
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Abstract The new mixed ligand palladium(II) complex of formula cis-Cl- [PdCl 2 (TPP)(MTUC)]·3(H 2 O) ( 1 ) was obtained by reacting 6-methyl-thiouracil (MTUC) with triphenylphosphine (TPP). The complex was characterized by vibrational spectroscopy (FT-IR), 1 H NMR, UV–Vis spectroscopic techniques and its structure was confirmed by X-ray crystallography. Mixed ligand complexes of palladium(II) dichloride with thiones and phosphines are very rare in the literature. Compound 1 is the fourth of this...
#1G. Malandrinos (UoI: University of Ioannina)H-Index: 1
#2Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
Abstract In this review, we summarize the research work performed in the last years to elucidate the Cu(II) induced toxicity-carcinogenesis mechanisms based on studies of Cu(II) interactions with histone model peptides the most abundant protein part of cell nucleus. Oligopeptide models of histones, synthesized and used in most cases, helped us to determine stoichiometry, binding sites, conformations adopted and DNA damage caused by the metal. They are all reviewed and discussed, in an attempt to...
#1I.I. Ozturk (Namik Kemal University)H-Index: 9
#2Apostolos Metsios (UoI: University of Ioannina)H-Index: 9
Last.Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
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Crystals of the [SbBr3(MMBZT)2] (1) complex (MMBZT = N-methyl-2-mercaptobenzothiazole) were grown from acetonitrile/methanol of the filtrate derived from the reaction between 3-methyl-2-mercaptobenzothiazole (MMBZT) in methanol, with antimony(III) bromide in acetonitrile. The crystal structure of 1 (C16H14Br3N2S4Sb) was determined by X-ray diffraction at 100(2) K, in space group P-1, with a = 10.738(2) A, b = 11.387(3) A, c = 11.439(3) A, α = 62.764°, β = 63.36(2)°, γ = 85.074(2)°, and Z = 2. Th...
#1D. B. Shpakovsky (UoI: University of Ioannina)H-Index: 1
#2C.N. Banti (UoI: University of Ioannina)H-Index: 16
Last.K. Charalabopoulos (UoI: University of Ioannina)H-Index: 12
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Four new organotin(IV) complexes of bis-(2,6-di-tert-butylphenol)tin(IV) dichloride [(tert-Bu-)2(HO-Ph)]2SnCl2 (1) with the heterocyclic thioamides 2-mercapto-pyrimidine (PMTH), 2-mercapto-4-methyl-pyrimidine (MPMTH), 2-mercapto-pyridine (PYTH) and 2-mercapto-benzothiazole (MBZTH), of formulae {[(tert-Bu-)2(HO-Ph)]2Sn(PMT)2} (2), {[(tert-Bu-)2(HO-Ph)]2Sn(MPMT)2} (3), {[(tert-Bu-)2(HO-Ph)]2SnCl(PYT)} (4) and {[(tert-Bu-)2(HO-Ph)]2SnCl(MBZT)} (5), have been synthesized and characterized by element...
#1Vasilis I. Balas (UoI: University of Ioannina)H-Index: 1
#2C.N. Banti (UoI: University of Ioannina)H-Index: 16
Last.Maciej Kubicki (Adam Mickiewicz University in Poznań)H-Index: 30
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Crystals of Ph3SnCl (1) were grown from a methanol/acetonitrile solution. Compounds [Ph3SnOH]n (2) and [(Ph2Sn)4Cl2O2(OH)2] (3) were crystallized from diethyl ether/methanol/acetonitrile and hot acetone/water solutions respectively, of the white precipitation, formed by adding KOH to solutions of 1 and [Ph2SnCl2] in 1 : 1 and 1 : 2 molar ratios respectively. Complex 1 was characterized by X-ray crystallography. X-ray structure determination of compounds 2 and 3 confirmed the previously reported ...
#1Nick Hadjiliadis (UoI: University of Ioannina)H-Index: 36
#2Curt Wentrup (UQ: University of Queensland)H-Index: 36
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