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Alberto Ascherio
Harvard University
456Publications
116H-index
52.8kCitations
Publications 456
Newest
Published on Apr 3, 2019in Neurology 8.05
Marianna Cortese6
Estimated H-index: 6
,
Tanuja Chitnis46
Estimated H-index: 46
+ 1 AuthorsKarl Münger66
Estimated H-index: 66
Objective To investigate the association between mineral intake (potassium, magnesium, calcium, phosphorus, iron, zinc, manganese, copper) and multiple sclerosis (MS) risk. Methods In a prospective cohort study, we assessed dietary and supplemental mineral intake by a validated food frequency questionnaire administered every 4 years to 80,920 nurses in the Nurses9 Health Study (1984–2002) and 94,511 in the Nurses9 Health Study II (1991–2007). There were 479 new MS cases during follow-up. We esti...
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Published on Apr 1, 2019in American Journal of Epidemiology 4.32
Zeyan Liew12
Estimated H-index: 12
(Yale University),
Marianthi-Anna Kioumourtzoglou5
Estimated H-index: 5
(Columbia University)
+ 3 AuthorsMarc G. Weisskopf50
Estimated H-index: 50
(Harvard University)
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Published on Apr 1, 2019in Annals of Neurology 10.25
Rachit Bakshi9
Estimated H-index: 9
(Harvard University),
Eric A. Macklin35
Estimated H-index: 35
(Harvard University)
+ 7 AuthorsMichael A. Schwarzschild66
Estimated H-index: 66
(Harvard University)
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Published on Mar 29, 2019in Neurology 8.05
Kjetil Bjørnevik9
Estimated H-index: 9
,
Zhongli Zhang + 19 AuthorsLaurence N. Kolonel100
Estimated H-index: 100
Objective To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic lateral sclerosis (ALS). Methods We conducted a global metabolomic study using a nested case-control study design within 5 prospective cohorts and identified 275 individuals who developed ALS during follow-up. We profiled plasma metabolites using liquid chromatography–mass spectrometry and identified 404 known metabolites. We used conditional logistic regression to evaluate the associations between meta...
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Published on Jan 1, 2019in Neurology 8.05
Changzheng Yuan9
Estimated H-index: 9
,
Elinor Fondell8
Estimated H-index: 8
+ 4 AuthorsBarry M. Popkin319
Estimated H-index: 319
Objective To evaluate the prospective association of long-term intake of vegetables and fruits with late-life subjective cognitive function (SCF). Methods Among 27,842 men with a mean age of 51 years in 1986, we used multinomial logistic regression to examine the relation of vegetable and fruit consumption to future SCF. Average dietary intake was calculated from 5 repeated food frequency questionnaires collected every 4 years until 2002. SCF score was assessed twice (2008 and 2012) using a 6-it...
2 Citations Source Cite
Published on Jan 1, 2019in Multiple sclerosis and related disorders 3.20
Hilda J.I. de Jong1
Estimated H-index: 1
(Maastricht University),
Helen Tremlett37
Estimated H-index: 37
(Vancouver Coastal Health)
+ 2 AuthorsKarl Münger66
Estimated H-index: 66
(Harvard University)
Abstract Background Whether animal exposure and specifically the timing of such exposure alters multiple sclerosis (MS) risk is unclear. We examined whether animal exposure was associated with MS risk, and whether risk differed by the participants' age. Methods We conducted a case-control study within the Nurses’ Health Study ((NHS)/NHSII cohorts). Overall, 151 women with MS and 235 controls, matched by age and study cohort, completed an animal exposure history questionnaire. Animal exposure pre...
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Published on Jan 1, 2019in Movement Disorders 8.32
Alberto Ascherio116
Estimated H-index: 116
(Harvard University),
Michael A. Schwarzschild66
Estimated H-index: 66
(Harvard University)
1 Citations Source Cite
Published on Dec 11, 2018in Neurology 8.05
Ruth Ann Marrie38
Estimated H-index: 38
,
Helmut Butzkueven41
Estimated H-index: 41
,
Alberto Ascherio116
Estimated H-index: 116
Pathologically, multiple sclerosis (MS) is characterized by inflammation and neurodegeneration; the latter is the substrate of loss of brain volume, detectable by serial MRI. Clinically, MS is often characterized by progressive cognitive and physical impairment, and these impairments are associated with changes in brain volume. The accessibility of brain volume measurement and ability to determine change over relatively short periods make it a potentially useful phenotype for studying prognostic...
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Katherine C. Hughes7
Estimated H-index: 7
(Harvard University),
Xiang Gao52
Estimated H-index: 52
(Pennsylvania State University)
+ 5 AuthorsAlberto Ascherio116
Estimated H-index: 116
Background Several non-motor features may individually contribute to identify prodromal Parkinson’s disease (PD), but little is known on how they interact. Methods We conducted a case–control study nested within the Health Professionals Follow-up Study in a large cohort of men age 40–75 at recruitment in 1986. Cases (n=120) had confirmed PD, were Results Concurrent constipation, probable RBD and hyposmia were present in 29.3% of cases and 1.1% of controls, yielding an age-adjusted OR of 160 (95%...
2 Citations Source Cite
Published on Nov 14, 2018in Neurology 8.05
Kjetil Bjørnevik9
Estimated H-index: 9
,
Éilis J. O'Reilly32
Estimated H-index: 32
+ 13 AuthorsSabrina Paganoni13
Estimated H-index: 13
Objective To assess whether prediagnostic levels of plasma branched-chain amino acids (BCAAs) are associated with amyotrophic lateral sclerosis (ALS) risk. Methods We included participants from 5 large cohort studies—The Nurses9 Health Study, the Health Professionals Follow-up Study, the Cancer Prevention Study II Nutrition, the Multiethnic Cohort Study, and the Women9s Health Initiative—and identified 275 individuals who developed ALS during follow-up. Two controls were randomly selected for ea...
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