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David Braunholtz
University of Birmingham
43Publications
24H-index
2,488Citations
Publications 43
Newest
#1Julia HusseinH-Index: 22
#2David BraunholtzH-Index: 24
Last.Lucia D'AmbruosoH-Index: 12
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Source
#1Neil P. Johnson (University of Auckland)H-Index: 34
#2Rosalie A. Fisher (University of Auckland)H-Index: 1
Last.Richard J. Lilford (University of Birmingham)H-Index: 70
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Objective: To evaluate clinicians’ beliefs concerning the effectiveness of lipiodol flushing as a treatment for unexplained infertility, and to integrate these prior beliefs with evidence from randomised trials. Design: Survey. Setting: Specialists in Australasian in vitro fertilisation (IVF) clinics in 2001. Methods: One of two types of structured survey was used to gather information from fertility specialists in Australasian IVF clinics. Prior beliefs were captured graphically and textually f...
6 CitationsSource
#1Richard J. LilfordH-Index: 70
#2Alan GirlingH-Index: 28
Last.David BraunholtzH-Index: 24
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Assessments of cost effectiveness are increasingly used to get the most value from limited health resources. Could adjusting for people who wouldn9t want the treatment improve the process?
2 CitationsSource
#1Sarah J. L. Edward (UoB: University of Bristol)H-Index: 1
#2Andrew Stevens (University of Birmingham)H-Index: 30
Last.Teresa Swift (UoB: University of Bristol)H-Index: 7
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Because of the recent and controversial example of sham surgery for the evaluation of fetal tissue transplants for Parkinson’s disease, there is renewed interest in the ethics of using “active” placebos in surgical trials, where otherwise there are no inert procedures available, and in pharmacological trials, where there are inert substances, but where patients may guess to which arm they have been allocated. This paper seeks to clarify the ethical arguments surrounding the use of active placebo...
30 CitationsSource
#2C. KerrH-Index: 4
Last.Martin RowleyH-Index: 7
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Objectives: To research the lay public's understanding of equipoise and randomisation in randomised controlled trials (RCTs) and to look at why information on this may not be not taken in or remembered, as well as the effects of providing information designed to overcome barriers.Design: Investigations were informed by an update of systematic review on patients' understanding of consent information in clinical trials, and by relevant theory and evidence from experimental psychology. Nine investi...
111 CitationsSource
#1Pallavi Latthe (University of Birmingham)H-Index: 19
#2David Braunholtz (University of Birmingham)H-Index: 24
Last.Richard J. Lilford (University of Birmingham)H-Index: 70
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To explore gynaecologists' ‘prior’ beliefs on effectiveness of laparoscopic uterosacral nerve ablation (LUNA), a structured survey was used to gather information on the distribution of their prior beliefs regarding the effects of LUNA on pelvic pain, both numerically [on a 10-point visual analogue scale] and by responses to a questionnaire. None of the 25 gynaecologists responding to the questionnaire stated that LUNA would increase pain, while two of the 25 gave numerical answers suggesting the...
13 CitationsSource
#1C. Kerr (Keele University)H-Index: 4
#2Elizabeth J. Robinson (Keele University)H-Index: 34
Last.Andrew Stevens (University of Birmingham)H-Index: 30
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Concern has been expressed over a possible widespread belief amongst patients in trials, that a new treatment is better than the standard, despite the lack of evidence of such superiority. A sample of the general public (N=130) read a leaflet describing a hypothetical trial comparing two similar treatments for either arthritis or back-pain. Half read that both treatments were standard and generally available; half that one was new and available only within the trial. Participants rated any prefe...
11 CitationsSource
#1C. Kerr (Keele University)H-Index: 4
#2Elizabeth J. Robinson (Keele University)H-Index: 34
Last.Richard J. Lilford (University of Birmingham)H-Index: 70
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Objective: To examine lay persons' ability to identify methods of random allocation and their acceptability of using methods of random allocation in a clinical trial context. Design: Leaflets containing hypothetical medical, non-medical, and clinical trial scenarios involving random allocation, using material from guidelines for trial information leaflets. Setting and participants: Adults attending further education colleges (n = 130), covering a wide range of ages, occupations, and levels of ed...
44 CitationsSource
#1Elizabeth J. Robinson (Keele University)H-Index: 34
#2C. Kerr (Keele University)H-Index: 4
Last.Sarah J L Edwards (UoB: University of Bristol)H-Index: 20
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Randomised controlled trials (RCTs) play a central role in modern medical advance, and they require participants who understand and accept the procedures involved. Published evidence suggests that RCT participants often fail to understand that treatments are allocated at random and that clinicians are in equipoise about which treatment is best. We examine background assumptions that members of the public might draw upon if invited to take part in a RCT. Four studies (N=82; 67; 67; 128), in the U...
66 CitationsSource
#1Richard J. Lilford (University of Birmingham)H-Index: 70
#2David Braunholtz (University of Birmingham)H-Index: 24
Last.T. Gill (University of Birmingham)H-Index: 1
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Background Trials in surgery pose some special problems. This paper examines these with reference to 10 years of methodological research sponsored by the UK National Health Service Research and Development programme. Methods Solutions to common problems encountered in surgical studies were considered, such as issues of blinding, dependence of results on technical skill and continued evolution of technology. Results Numerous methodological developments are described, including the tracker trial c...
91 CitationsSource
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