Myriam Barandiaran
Instituto de Salud Carlos III
Publications 14
Published on May 1, 2019in Neurobiology of Aging4.40
Timothy Rittman18
Estimated H-index: 18
(University of Cambridge),
Robin Borchert4
Estimated H-index: 4
(University of Cambridge)
+ 122 AuthorsFabrizio Tagliavini60
Estimated H-index: 60
The presymptomatic phase of neurodegenerative diseases are characterized by structural brain changes without significant clinical features. We set out to investigate the contribution of functional network resilience to preserved cognition in presymptomatic genetic frontotemporal dementia. We studied 172 people from families carrying genetic abnormalities in C9orf72, MAPT, or PGRN. Networks were extracted from functional MRI data and assessed using graph theoretical analysis. We found that despit...
Published on Apr 1, 2019in NeuroImage5.81
Enrico Premi17
Estimated H-index: 17
(University of Brescia),
Vince Daniel Calhoun87
Estimated H-index: 87
(UNM: University of New Mexico)
+ 130 AuthorsJohn VanSwieten68
Estimated H-index: 68
(EUR: Erasmus University Rotterdam)
Abstract Frontotemporal Dementia (FTD) is preceded by a long period of subtle brain changes, occurring in the absence of overt cognitive symptoms, that need to be still fully characterized. Dynamic network analysis based on resting-state magnetic resonance imaging (rs-fMRI) is a potentially powerful tool for the study of preclinical FTD. In the present study, we employed a "chronnectome" approach (recurring, time-varying patterns of connectivity) to evaluate measures of dynamic connectivity in 4...
Published on Nov 28, 2018in Frontiers in Aging Neuroscience3.63
Gorka Fernández-Eulate , Ainhoa Alberro2
Estimated H-index: 2
+ 19 AuthorsNora Soberón3
Estimated H-index: 3
Many factors may converge in healthy ageing in the oldest old, but their association and predictive power on healthy o functionally impaired ageing has yet to be demonstrated. By detecting healthy ageing and in turn, poor ageing, we could take action to prevent chronic diseases associated with age. We conducted a pilot study comparing results of a set of markers (peripheral blood mononuclear cell telomere length or PBMC, circulating Aβ peptides, anti-Aβ antibodies, and ApoE status) previously as...
Published on Sep 29, 2015in Journal of Alzheimer's Disease3.70
Pau Pastor31
Estimated H-index: 31
Fermin Moreno13
Estimated H-index: 13
+ 35 AuthorsEva Carro33
Estimated H-index: 33
Spanish Ministry of Science and Innovation SAF 2006-10126 (2006–2009) and SAF2010-22329-C02-01 (2011–2013) to P.P and by the UTE project FIMA to P.P. Grants from the Ministry of Science (SAF2010-15558) and CIBERNED. Agust´in Ruiz is supported by grant PI13/02434 (Accion Estrategica en Salud. Instituto de Salud Carlos III. Ministerio de Economia y Competitividad, Spain). Grant: Consolider (CSD2010-00045).
Published on Oct 1, 2014in Parkinsonism & Related Disorders4.36
A. Estanga1
Estimated H-index: 1
(UPV/EHU: University of the Basque Country),
Maria C. Rodriguez-Oroz32
Estimated H-index: 32
+ 6 AuthorsJosé Félix Martí Massó13
Estimated H-index: 13
(UPV/EHU: University of the Basque Country)
Objective: The neuropsychological characteristics of patients with Parkinson's Disease (PD) associated with R1441G mutation in the LRRK2 gene (R1441G-PD) are not well known. The aim of this study was to examine the cognitive status and mood of R1441G-PD patients. Methods: Thirty patients with R1441G-PD were compared with thirty idiopathic PD (i-PD) patients who were matched by age, sex, education, disease onset age and duration, using a comprehensive battery of neuropsychological test, and consi...
Published on May 1, 2013in Neurobiology of Aging4.40
Fermin Moreno13
Estimated H-index: 13
(ISCIII: Instituto de Salud Carlos III),
Roser Sala-Llonch22
Estimated H-index: 22
(University of Barcelona)
+ 9 AuthorsJosé Félix Martí Massó13
Estimated H-index: 13
(ISCIII: Instituto de Salud Carlos III)
Abstract Studies in asymptomatic granulin gene ( GRN ) mutation carriers are essential to improve our understanding of the pattern and timing of early morphologic brain changes in frontotemporal lobar degeneration. The main objectives of this study were to assess the effect of age in cortical thickness changes (CTh) in preclinical GRN mutation carriers and to study the relationship of CTh with cognitive performance in GRN mutation carriers. We calculated CTh maps in 13 asymptomatic carriers of t...
Published on Nov 1, 2012in Journal of The International Neuropsychological Society3.10
Myriam Barandiaran7
Estimated H-index: 7
Ainara Estanga10
Estimated H-index: 10
+ 5 AuthorsAdolfo López de Munain33
Estimated H-index: 33
Mutations in the progranulin (PGRN) gene have been identified as a cause of frontotemporal dementia (FTD). However, little is known about the neuropsychological abilities of asymptomatic carriers of these mutations. The aim of the study was to assess cognitive functioning in asymptomatic c.709-1G>A PGRN mutation carriers. We hypothesized that poorer neuropsychological performance could be present before the development of clinically significant FTD symptoms. Thirty-two asymptomatic first-degree ...
Published on Jan 1, 2012in Revista De Neurologia0.48
de la Riva P2
Estimated H-index: 2
Fermin Moreno13
Estimated H-index: 13
+ 3 AuthorsJ.F. Martí-Massó14
Estimated H-index: 14
Introduccion. La angiopatia amiloide inflamatoria (AAI) es una forma de presentacion infrecuente de la angiopatia amiloide cerebral recientemente reconocida y cuyo diagnostico definitivo es anatomopatologico. Objetivo. Se presenta un paciente con AAI con buena respuesta clinica, neuropsicologica y de neuroimagen al tratamiento con corticoides y en el que no se considero necesario practicar biopsia cerebral. Caso clinico. Varon de 68 anos con diagnostico de enfermedad de Alzheimer que sufrio una ...