Joseph R. Hibbeln
National Institutes of Health
Publications 182
#1Alexis C. Edwards (VCU: Virginia Commonwealth University)H-Index: 13
#2Jon Heron (UoB: University of Bristol)H-Index: 52
Last.Jill C. BettingerH-Index: 12
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#1Bernadette P. Marriott (MUSC: Medical University of South Carolina)H-Index: 6
#2Travis H. Turner (MUSC: Medical University of South Carolina)H-Index: 6
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Abstract Intake of nutrients fundamental for optimal neuronal function is of increasing interest. The potential importance of omega-3 highly unsaturated fatty acids (HUFAs) for optimizing emotional states, cognitive function, and mental health has been demonstrated in observational studies and randomized controlled trials. Omega-3 (HUFAs), specifically EPA (eicosapentaenoic acid) and docosahexaenoic acid (DHA), are concentrated in neural tissues and are essential for neural function, normative n...
#1Chuck T. Chen (NIH: National Institutes of Health)H-Index: 2
#2Joseph A. Schultz (NIH: National Institutes of Health)
Last.Joseph R. Hibbeln (NIH: National Institutes of Health)H-Index: 51
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#1Ta-Wei GuuH-Index: 1
#2David MischoulonH-Index: 43
Last.Kuan-Pin SuH-Index: 28
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Major depressive disorder (MDD) is a complex mental illness with unmet therapeutic needs. The antidepressant effects of ω–3 polyunsaturated fatty acids (n–3 PUFAs) have been widely reported. The subcommittee of the International Society for Nutritional Psychiatry Research organized an expert panel and conducted a literature review and a Delphi process to develop a consensus-based practice guideline for clinical use of n–3 PUFAs in MDD. The guideline focuses on 5 thematic areas: general concepts,...
1 CitationsSource
#1Adrian Raine (UPenn: University of Pennsylvania)H-Index: 82
#2Rebecca P. Ang (NTU: Nanyang Technological University)H-Index: 33
Last.Daniel S. S. FungH-Index: 20
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Background While studies suggest that nutritional supplementation may reduce aggressive behavior in children, few have examined their effects on specific forms of aggression. This study tests the primary hypothesis that omega-3 ( ω -3), both alone and in conjunction with social skills training, will have particular post-treatment efficacy for reducing childhood reactive aggression relative to baseline. Methods In this randomized, double-blind, stratified, placebo-controlled, factorial trial, a c...
1 CitationsSource
#1Jean Golding (UoB: University of Bristol)H-Index: 84
#2Dheeraj Rai (UoB: University of Bristol)H-Index: 22
Last.Caroline M Taylor (UoB: University of Bristol)H-Index: 12
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Background Mercury (Hg) has been suspected of causing autism in the past, especially a suspected link with vaccinations containing thiomersal, but a review of the literature shows that has been largely repudiated. Of more significant burden is the total quantity of Hg in the environment. Here, we have used the Avon Longitudinal Study of Parents and Children (ALSPAC) to test whether prenatal exposure from total maternal blood Hg in the first half of pregnancy is associated with the risk of autism...
3 CitationsSource
#1Jill PortnoyH-Index: 9
#2Adrian RaineH-Index: 82
Last.Joseph R. HibbelnH-Index: 51
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#1Joseph R. HibbelnH-Index: 51
#2Steven Gregory (UoB: University of Bristol)H-Index: 6
Last.Jean Golding (UoB: University of Bristol)H-Index: 84
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Abstract There is a public perception that relatively low doses of mercury found in seafood are harmful to the fetal brain but little consistent evidence to support this. In earlier publications we have shown no adverse associations between maternal total blood mercury levels and child behaviour, early development or cognitive function as measured by IQ. However, for IQ the lack of adverse association was conditional upon the mother being a fish eater. In this paper we analyse further data from ...
3 CitationsSource
Objectives: To assess whether serum concentrations of saturated (SFAs), polyunsaturated (PUFAs), and mono- unsaturated (MUFAs) fatty acids are associated with changes in blood pressure (BP) throughout pregnancy. Study design: Prospective cohort. Main outcome measures: Longitudinal measurements of systolic (SBP) and diastolic (DBP) BP. Methods: Two hundred twenty-three healthy pregnant women were recruited in a public health center in Rio de Janeiro, Brazil between 2009 and 2011. Fasting blood sa...
#1V GowRachel (NIH: National Institutes of Health)H-Index: 10
#2Jon Heron (UoB: University of Bristol)H-Index: 52
Last.John Paul SanGiovanni (NIH: National Institutes of Health)H-Index: 32
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n-3 Highly unsaturated fatty acids (HUFA), are essential components of neuronal membranes and mediate a range of complex bioactive properties including gene expression, myelination, cell-signalling and dopaminergic function. Deficits in n-3 HUFA have been linked to increased risks for addictive disorders, thus we posited that lower fish consumption would be associated with greater risks for perinatal smoking among 9640 mothers enroled in the Avon Longitudinal Study of Parents and Children. We us...