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Buddy D. Ratner
University of Washington
Analytical chemistryOrganic chemistryChemistryMaterials sciencePolymer
573Publications
88H-index
27.5kCitations
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#1Courtney Cottone (UCI: University of California, Irvine)H-Index: 1
#2Sherry Lu (UCI: University of California, Irvine)
Last. Kathleen R. Johnson (UCI: University of California, Irvine)H-Index: 22
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INTRODUCTION: Encrustation of implanted urinary tract devices is associated with significant morbidity. Pellethane(R) is a polyether-based compound noted for its strength, porosity and resistance to solvents. We assessed Pellethane(R) thermoplastic polyurethane (TPU) with and without surface coatings 2-hydroxyethyl methacrylate (HEMA) and tetraethylene glycol dimethyl ether (TETRA) for the potential to resist encrustation in an artificial urine environment. METHODS: Samples of Pellethane(R) TPU,...
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#1Helena D. Zomer (UFSC: Universidade Federal de Santa Catarina)H-Index: 4
#1Helena D. Zomer (UFSC: Universidade Federal de Santa Catarina)H-Index: 1
Last. Andrea Gonçalves Trentin (UFSC: Universidade Federal de Santa Catarina)H-Index: 2
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Abstract The process of wound healing restores skin homeostasis but not full functionality; thus, novel therapeutic strategies are needed to accelerate wound closure and improve the quality of healing. In this context, tissue engineering and cellular therapies are promising approaches. Although sharing essential characteristics, mesenchymal stromal cells (MSCs) isolated from different tissues might have distinct properties. Therefore, the aim of this study was to comparatively investigate, by a ...
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#1David G. Castner (UW: University of Washington)H-Index: 50
#2Buddy D. Ratner (UW: University of Washington)H-Index: 88
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#1Erasmo Lopez Calleros (UW: University of Washington)
#2Felix I. Simonovsky (UW: University of Washington)H-Index: 6
Last. Buddy D. Ratner (UW: University of Washington)H-Index: 88
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#1Marvin M. Mecwan (UW: University of Washington)
#2Michael Taylor (UW: University of Washington)H-Index: 16
Last. Buddy D. Ratner (UW: University of Washington)H-Index: 88
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New surface initiators for ARGET ATRP (activators regenerated by electron transfer atomic transfer radical polymerization) have been prepared by the plasma deposition of haloester monomers. Specifically, methyl 3-bromopropionate (M3BP), methyl 2-chloropropionate, and ethyl 2-fluoropropionate (E2FP) were plasma deposited onto glass discs using RF glow discharge plasma. This technique creates surface coatings that are resistant to delamination and rich in halogen species making them good candidate...
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#1Razieh Khalifehzadeh (UW: University of Washington)H-Index: 2
#2Buddy D. Ratner (UW: University of Washington)H-Index: 88
Fluorinated polymers are strong candidates for development of new cardiovascular medical devices, due to their lower thrombogenicity as compared to other polymers used for cardiovascular implants. Few studies have reported the development of fluorinated polyesters and their potential in blood contact applications has never been examined. In this study, we developed a versatile method for preparing trifluoromethyl-functionalized poly(lactic acid) that can be potentially extended to prepare a new ...
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#1Buddy D. RatnerH-Index: 1
Biomaterials as we know them today had their origins in the late 1940s with off-the-shelf commercial polymers and metals. The evolution of materials for medical applications from these simple origi...
1 CitationsSource
#1Irini Sotiri (UW: University of Washington)H-Index: 1
#2Matthew Robichaud (UW: University of Waterloo)H-Index: 2
Last. Ilya Reviakine (UW: University of Washington)H-Index: 10
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Abstract From stents and large-diameter vascular grafts, to mechanical heart valves and blood pumps, blood-contacting devices are enjoying significant clinical success owing to the application of systemic antiplatelet and anticoagulation therapies. On the contrary, research into material and device hemocompatibility aimed at alleviating the need for systemic therapies has suffered a decline. This research area is undergoing a renaissance fueled by recent fundamental insights into coagulation and...
3 CitationsSource
#1Razieh Khalifehzadeh (UW: University of Washington)H-Index: 2
#2Winston Ciridon (UW: University of Washington)H-Index: 4
Last. Buddy D. Ratner (UW: University of Washington)H-Index: 88
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Abstract Surface-induced thrombosis is still a significant clinical concern for many types of blood-contacting medical devices. In particular, protein adsorption and platelet adhesion are important events due to their ability to trigger the coagulation cascade and initiate thrombosis. Poly(lactic acid) (PLA) has been the predominant polymer used for making bioresorbable stents. Despite long-term advantages, these stents are associated with higher rates of early thrombosis compared with permanent...
5 CitationsSource
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