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Dave Capener
University of Sheffield
Magnetic resonance imagingCardiologyPulmonary hypertensionPulmonary arteryMedicine
45Publications
14H-index
714Citations
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Publications 34
Newest
#1Andrew J. Swift (University of Sheffield)H-Index: 26
#2Krit Dwivedi (University of Sheffield)
Last. Charlie Elliot (Royal Hallamshire Hospital)H-Index: 23
view all 17 authors...
OBJECTIVES: Computed tomography (CT) pulmonary angiography is widely used in patients with suspected pulmonary hypertension (PH). However, the diagnostic and prognostic significance remains unclear. The aim of this study was to (a) build a diagnostic CT model and (b) test its prognostic significance. METHODS: Consecutive patients with suspected PH undergoing routine CT pulmonary angiography and right heart catheterisation (RHC) were identified. Axial and reconstructed images were used to derive ...
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#1Andrew J. SwiftH-Index: 26
#2Marcella CoglianoH-Index: 2
Last. Jim M. WildH-Index: 41
view all 14 authors...
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#1David G. KielyH-Index: 40
#2Andrew J. SwiftH-Index: 26
Last. Jim M. WildH-Index: 41
view all 17 authors...
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Rationale: Prognostication is important when counseling patients and defining treatment strategies in pulmonary arterial hypertension (PAH).Objectives: To determine the value of magnetic resonance imaging (MRI) metrics for prediction of mortality in PAH.Methods: Consecutive patients with PAH undergoing MRI were identified from the ASPIRE (Assessing the Spectrum of Pulmonary Hypertension Identified at a Referral Centre) pulmonary hypertension registry.Measurements and Main Results: During the fol...
32 CitationsSource
#1Christopher S. Johns (University of Sheffield)H-Index: 7
#2Dave Capener (University of Sheffield)H-Index: 14
Last. Andrew J. Swift (University of Sheffield)H-Index: 26
view all 9 authors...
Pulmonary hypertension (PH) is important in COPD as it is a predictor of hospitalization and death. The gold standard for diagnosis is right heart catheterisation (RHC), an invasive test. Patients are screened using echo, but this is less successful in COPD due to hyperinflation. The aim of this study was to assess a noninvasive model of mPAP estimation using cardiopulmonary MRI. Consecutive patients with COPD referred to a PH centre from 2012 to 2016 were reviewed. Biventricular volumes, mass a...
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#1Euan Tubman (University of Sheffield)H-Index: 2
#2Tom Sproson (University of Sheffield)H-Index: 2
Last. Andrew J. Swift (University of Sheffield)H-Index: 26
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Introduction: Pulmonary arterial hypertension is defined at cardiac catheterization as a mPAP≥ 25 mmHg and a pulmonary arterial wedge pressure (PAWP) ≤15mmHg. The presence of cardiac comorbidities is associated with a poorer response to therapy in patients with PAH and left ventricular diastolic dysfunction may exist even in the presence of a normal resting PAWP. The aim of this study was to use left atrial volume as a surrogate of left ventricular diastolic dysfunction in patients with normal P...
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#1Kieran Shotton (University of Sheffield)
#2Henry Walker (University of Sheffield)H-Index: 1
Last. Andrew J. Swift (University of Sheffield)H-Index: 26
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Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure (mPAP) ≥ 25mmHg at right heart catheterization. An mPAP of 21-24mmHg is termed borderline PH. This study investigates cardiac magnetic resonance (CMR) imaging characteristics of patients with borderline PH. Consecutive patients who underwent CMR at 1.5T at a PH centre between April 2012 and January 2016 were identified. Exclusion criteria were non-diagnostic imaging or RHC >48 hours from CMR. All variables were compared b...
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#1Andrew J. Swift (University of Sheffield)H-Index: 26
#2Angela Lungu (University of Sheffield)H-Index: 5
Last. Jim M. Wild (University of Sheffield)H-Index: 41
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Introduction: In contrast to the systemic arterial system, the association between age and compliance in the pulmonary circulation has to date not been investigated in vivo. The aim of this study was to evaluate the impact of age on pulmonary arterial compliance in health and in patients with pulmonary arterial hypertension (PAH). Methods: Consecutive patients with No PH (mPAP Results: 151 patients with PAH (57 underwent follow up RHC), 83 patients with No PH were identified and 34 healthy volun...
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#1Euan Tubman (University of Sheffield)H-Index: 2
#2Tom Sproson (University of Sheffield)H-Index: 2
Last. Andrew J. Swift (University of Sheffield)H-Index: 26
view all 9 authors...
Background In contrast to the considerable literature on the prognostic value of right ventricular metrics at baseline and follow-up in PAH, the prognostic value of right atrial size and function has been less well studied. The aim of this study was to compare the prognostic value of right atrial length, area and volume measurements in treatment naive patients with PAH and the impact of treatment. Methods Patients with PAH who underwent MRI at baseline and follow up on a 1.5 T MRI scanner were i...
1 CitationsSource
#1Andrew J. Swift (University of Sheffield)H-Index: 26
#2Smitha Rajaram (University of Sheffield)H-Index: 17
Last. David G. KielyH-Index: 40
view all 7 authors...
Right ventricular (RV) function is a strong predictor of outcome in cardiovascular diseases. Two components of RV function, longitudinal and transverse motion, have been investigated in pulmonary hypertension (PH). However, their individual clinical significance remains uncertain. The aim of this study was to determine the factors associated with transverse and longitudinal RV motion in patients with PH. In 149 treatment-naive patients with PH and 16 patients with suspected PH found to have mean...
9 CitationsSource
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