C. Verdich
Copenhagen University Hospital
Publications 27
#1C. VerdichH-Index: 17
#2Anne RabenH-Index: 34
Last.Thorkild I. A. SørensenH-Index: 95
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#1C. VerdichH-Index: 17
#2P. BarbeH-Index: 20
Last.J.-M. OppertH-Index: 12
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#1C. Verdich (Copenhagen University Hospital)H-Index: 17
#2P. Barbe (University of Toulouse)H-Index: 20
Last.J.-M. OppertH-Index: 12
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Abstract Aim We studied the accuracy of bioelectrical impedance analysis (BIA) to assess changes in body composition during moderate weight loss in obese subjects. Methods Estimates of changes in fat mass (FM) and fat-free mass (FFM) by BIA were compared with those by dual-energy X-ray absorptiometry (DXA) as the reference method during a 10-week standardized weight-loss intervention. In obese women (age: 20–50years, mean BMI: 33.8kg/m 2 ) participating in a European multicentre trial (nutrient–...
36 CitationsSource
#1Tune H. Pers (UCPH: University of Copenhagen)H-Index: 45
#2F. Martin (Nestlé)H-Index: 4
Last.Ziad Ramadan (Nestlé)H-Index: 17
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Abstract There is evidence from clinical trials that a low capacity to oxidize dietary fats may predispose human individuals to weight gain, obesity, and weight regain following weight loss. These observations have led to a need to identify plasma markers of fat oxidation capacity in order to avoid time consuming direct measurements by indirect calorimetry. The aim of this study was to investigate whether prediction of fat oxidation capacity in an obese population is possible, using 1 H-NMR and ...
5 CitationsSource
#1Jan Polak (Charles University in Prague)H-Index: 23
#2Zuzana KovacovaH-Index: 15
Last.V. StichH-Index: 8
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Aim: Adiponectin increases insulin sensitivity, protects arterial walls against atherosclerosis, and regulates glucose metabolism, and is decreased in obese, insulin resistant, and type 2 diabetic patients. Adiponectin circulates in plasma as high, medium, and low molecular weight forms (HMW, MMW, and LMW). The HMW form was suggested to be closely associated with insulin sensitivity. This study investigated whether diet-induced changes in insulin sensitivity were associated with changes in adipo...
28 CitationsSource
#1Anne Flint (Novo Nordisk)H-Index: 31
Last.A. AstrupH-Index: 96
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It is unclear whether postprandial blood glucose or insulin exerts a regulatory function in short-term appetite regulation in humans. The aim of this study was to investigate, by use of meta-analysis, the role of blood glucose and insulin in short-term appetite sensation and energy intake (El) in normal weight and overweight participants. Data from seven test meal studies were used, including 136 healthy participants (ALL) (92 normal weight (NW) and 44 overweight or obese (OW)). All meals were s...
127 CitationsSource
#1Ellen E. BlaakH-Index: 58
#2Gabby B. J. HulH-Index: 18
Last.Wim H. M. SarisH-Index: 95
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Objectives: To study energy expenditure before and 3 hours after a high-fat load in a large cohort of obese subjects (n=701) and a lean reference group (n = 113). Research Methods and Procedures: Subjects from seven European countries underwent a 1-day clinical study with a liquid test meal challenge containing 95% fat (energy content was 50% of estimated resting energy expenditure). Fasting and 3-hour postprandial energy expenditures, as well as metabolites and hormones, were determined. Result...
22 CitationsSource
#1José Luis Santos (University of Navarra)H-Index: 27
#2Philippe Boutin (Pasteur Institute)H-Index: 28
Last.José Alfredo Martínez (University of Navarra)H-Index: 83
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Background The development of obesity is influenced by both genetic and environmental risk factors. Whereas changes in the environment appear to be responsible for the increasing prevalence of obesity, genetic factors interacting with environmental factors would contribute to explain obesity onset and severity.
41 CitationsSource
#2Philippe Boutin (Pasteur Institute)H-Index: 28
Last.Philippe Froguel (Pasteur Institute)H-Index: 141
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OBJECTIVES: To study if genes with common single nucleotide polymorphisms (SNPs) associated with obesity-related phenotypes influence weight loss (WL) in obese individuals treated by a hypo-energetic low-fat or high-fat diet. DESIGN: Randomised, parallel, two-arm, open-label multi-centre trial. SETTING: Eight clinical centres in seven European countries. PARTICIPANTS: 771 obese adult individuals. INTERVENTIONS: 10-wk dietary intervention to hypo-energetic (-600 kcal/d) diets with a targeted fat ...
69 CitationsSource
#1Ellen E. Blaak (UM: Maastricht University)H-Index: 58
#2Gabby B. J. Hul (UM: Maastricht University)H-Index: 18
Last.Wim H. M. Saris (UM: Maastricht University)H-Index: 95
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Background: Obesity may be associated with a lowered use of fat as a fuel, which may contribute to the enlarged adipose tissue stores. Aim: The aim of the present study was to study fatty acid use in the fasting state and in response to a high fat load in a large cohort of obese subjects (n = 701) and a lean reference group (n = 113). Methods: Subjects from eight European centers underwent a test meal challenge containing 95 en% fat [energy content 50% of estimated resting energy expenditure (EE...
63 CitationsSource