Marc G. Besselink
University of Amsterdam
Publications 641
#1Lei Huang (DKFZ: German Cancer Research Center)H-Index: 2
#2Yesilda Balavarca (DKFZ: German Cancer Research Center)H-Index: 7
Last.Lina Jansen (DKFZ: German Cancer Research Center)H-Index: 26
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Background Pancreatic cancer (PaC) remains extremely lethal worldwide even after resection. PaC resection rates are low, making prognostic studies in resected PaC difficult. This large international population-based study aimed at exploring factors associated with survival in patients with resected TNM stage I–II PaC receiving chemotherapy and at developing and internationally validating a survival-predicting model.
3 CitationsSource
#1Janneke van Grinsven (UvA: University of Amsterdam)H-Index: 7
#2Sven M. van Dijk (UvA: University of Amsterdam)
Last.Marc G. Besselink (UvA: University of Amsterdam)H-Index: 50
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Background Infected necrosis complicates 10% of all acute pancreatitis episodes and is associated with 15–20% mortality. The current standard treatment for infected necrotizing pancreatitis is the step-up approach (catheter drainage, followed, if necessary, by minimally invasive necrosectomy). Catheter drainage is preferably postponed until the stage of walled-off necrosis, which usually takes 4 weeks. This delay stems from the time when open necrosectomy was the standard. It is unclear whether ...
#1Stefan HeinrichH-Index: 30
#2Marc G. Besselink (UvA: University of Amsterdam)H-Index: 50
Last.Mickael Lesurtel (University of Lyon)H-Index: 28
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Background Several new treatment options have become available for pancreatic ductal adenocarcinoma (PDAC), but the support for their use for resectable, borderline resectable and locally advanced PDAC is unclear.
1 CitationsSource
#1Florian E. Buisman (EUR: Erasmus University Rotterdam)H-Index: 3
#2Marjolein Y.V. Homs (EUR: Erasmus University Rotterdam)H-Index: 12
Last.Bas Groot Koerkamp (EUR: Erasmus University Rotterdam)H-Index: 22
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Background: Recurrences are reported in 70% of all patients after resection of colorectal liver metastases (CRLM), in which half are confined to the liver. Adjuvant hepatic arterial infusion pump (HAIP) chemotherapy aims to reduce the risk of intrahepatic recurrence. A large retrospective propensity score analysis demonstrated that HAIP chemotherapy is particularly effective in patients with low-risk oncological features. The aim of this randomized controlled trial (RCT) -the PUMP trial- is to i...
2 CitationsSource
#1Nadine C. M. van Huijgevoort (UvA: University of Amsterdam)H-Index: 3
#2Marco del Chiaro (Anschutz Medical Campus)
Last.Marc G. Besselink (UvA: University of Amsterdam)H-Index: 50
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Pancreatic cystic neoplasms (PCN) are a heterogeneous group of pancreatic cysts that include intraductal papillary mucinous neoplasms, mucinous cystic neoplasms, serous cystic neoplasms and other rare cystic lesions, all with different biological behaviours and variable risk of progression to malignancy. As more pancreatic cysts are incidentally discovered on routine cross-sectional imaging, optimal surveillance for patients with PCN is becoming an increasingly common clinical problem, highlight...
#1A. Marthe Schreuder (UvA: University of Amsterdam)
#2Anton F. Engelsman (UvA: University of Amsterdam)H-Index: 11
Last.Olivier R. C. Busch (UvA: University of Amsterdam)H-Index: 54
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Abstract Introduction Whereas distal cholangiocarcinoma (DC) is treated by pancreatoduodenectomy (PD), consensus is lacking on treatment of mid-bile duct carcinoma (mid-BDC) without involvement of the pancreatic head. Both PD or a local resection (LR) of the extrahepatic bile duct with lymphadenectomy are being used. The aim of this study was to compare outcomes after PD and LR for mid-BDC and, for reference, PD for DC. Methods Retrospective monocenter study including consecutive patients who un...
#1Samira Fegrachi (UU: Utrecht University)H-Index: 3
#2Marieke S. Walma (UU: Utrecht University)H-Index: 2
Last.Richard van Hillegersberg (UU: Utrecht University)H-Index: 36
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Abstract Introduction Radiofrequency ablation (RFA) has been proposed as a new treatment option for locally advanced, unresectable pancreatic cancer (LAPC). In preparation of a randomized controlled trial (RCT), the aim of this phase II study was to assess the safety of RFA for patients with LAPC. Materials and methods Patients diagnosed with LAPC confirmed during surgical exploration between November 2012 and April 2014 were eligible for inclusion. RFA probes were placed under ultrasound guidan...
#1Lois A. DaamenH-Index: 5
#2Vincent P. GrootH-Index: 9
Last.Martijn W. J. Stommel (Radboud University Nijmegen)H-Index: 6
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Abstract Background The aim of this study is to collect the best available evidence for diagnostic modalities, frequency, and duration of surveillance after resection for pancreatic ductal adenocarcinoma (PDAC). Methods PDAC guidelines published after 2015 were collected. Furthermore, a systematic search of the literature on postoperative surveillance was performed in PubMed and Embase from 2000 to 2019. Articles comparing different diagnostic modalities and frequencies of postoperative surveill...
#1Mathieu D’HondtH-Index: 3
#2Edward WillemsH-Index: 1
Last.Chris Verslype (Katholieke Universiteit Leuven)H-Index: 44
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Abstract Background With growing popularity and experience in laparoscopic liver surgery, the options for more difficult procedures increase. Only small case series have been published regarding laparoscopic liver resection (LLR) for tumours in proximity to major vessels (MVs). The aim was to compare outcomes of LLR for tumours located less or more than 15 mm from MVs. Methods This was a retrospective analysis of a prospectively collected database of consecutive LLR (October 2011–August 2017). P...
#1Sjors KlompmakerH-Index: 7
#2Thijs de RooijH-Index: 13
Last.A. James MoserH-Index: 29
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