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Annemieke Ruitenberg
Erasmus University Rotterdam
27Publications
17H-index
4,387Citations
Publications 27
Newest
#1Leonie J.M. Vergouw (EUR: Erasmus University Rotterdam)H-Index: 3
#2Annemieke Ruitenberg (EUR: Erasmus University Rotterdam)H-Index: 17
Last.Marialuisa Quadri (EUR: Erasmus University Rotterdam)H-Index: 13
view all 11 authors...
Abstract Objective To analyse LRP10 variants, recently associated with the development of Parkinson's disease (PD), Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), in a series of patients and controls from the South-West of the Netherlands (Walcheren). Methods A series of 130 patients with PD, PDD or DLB were clinically examined, and a structured questionnaire used to collect information about family history of PD and dementia. The entire LRP10 coding region was sequenced...
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#1Inger R. de Ridder (EUR: Erasmus University Rotterdam)H-Index: 5
#2Heleen M. den Hertog (Medisch Spectrum Twente)H-Index: 18
Last.Diederik W.J. Dippel (EUR: Erasmus University Rotterdam)H-Index: 51
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Background and Purpose—Subfebrile body temperature and fever in the first days after stroke are strongly associated with unfavorable outcome. A subgroup analysis of a previous trial suggested that early treatment with paracetamol may improve functional outcome in patients with acute stroke and a body temperature of ≥36.5°C. In the present trial, we aimed to confirm this finding. Methods—PAIS 2 (Paracetamol [Acetaminophen] in Stroke 2) was a multicenter, randomized, double-blind, placebo-controll...
8 CitationsSource
#2Mirjam I. GeerlingsH-Index: 49
Last.Monique M.B. BretelerH-Index: 142
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Background: Increased levels of inflammatory proteins have been found in the brains and plasma samples of patients with dementia. Whether the levels of inflammatory proteins in plasma samples are elevated before clinical onset of dementia is unclear. Objective: To determine whether high levels of inflammatory proteins in plasma samples are associated with an increased risk of dementia. Design and Setting: A case-cohort study within the Rotterdam Study, a population-based prospective cohort study...
31 Citations
#1Inger R. de Ridder (EUR: Erasmus University Rotterdam)H-Index: 5
#2Jong de F. J (EUR: Erasmus University Rotterdam)H-Index: 20
Last.Diederik W.J. Dippel (EUR: Erasmus University Rotterdam)H-Index: 51
view all 16 authors...
Rationale: In the first hours after stroke onset, subfebrile temperatures and fever have been associated with poor functional outcome. In the first Paracetamol (Acetaminophen) in Stroke trial, a randomized clinical trial of 1400 patients with acute stroke, patients who were treated with high-dose paracetamol showed more improvement on the modified Rankin Scale at three-months than patients treated with placebo, but this difference was not statistically significant. In the 661 patients with a bas...
19 CitationsSource
textabstractAn increase in body temperature in the first days following stroke is related to poor functional outcome. High-dose paracetamol (acetaminophen) reduces the body temperature by 0.3°C and can prevent fever. Paracetamol treatment is simple, cheap and has few side effects. In the first "Paracetamol (Acetaminophen) in Stroke" (PAIS) study, there was a beneficial effect of high-dose paracetamol on functional outcome in patients with stroke and a body temperature of 37.0°C or above. Because...
#1Mirjam I. GeerlingsH-Index: 49
Last.Jacqueline C. M. WittemanH-Index: 135
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A 76-year-old woman presented with syncope. The next day she had disorientation, confabulations, slight dyspraxia of the left hand and bilateral Babinski signs. A fluid attenuated inversion recovery MR scan showed high signal intensity of the head of the caudate nuclei, the anterior part of the corpus callosum and the fornices, consistent with bilateral …
7 CitationsSource
#1Joleen H. Blok (EUR: Erasmus University Rotterdam)H-Index: 19
#2Annemieke Ruitenberg (EUR: Erasmus University Rotterdam)H-Index: 17
Last.Gerhard H. Visser (EUR: Erasmus University Rotterdam)H-Index: 17
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This study aims to assess the potential of the electrophysiological muscle scan or stimulus-response curve as a diagnostic instrument. If stimulus intensity is gradually increased from subthreshold to supramaximal values, all motor units in a muscle are successively activated. Thus, by plotting response size versus stimulus intensity, an impression (scan) of the entire muscle can be obtained. We recorded 54 detailed scans from 34 patients and 11 healthy subjects, and analyzed them visually and q...
31 CitationsSource
#1Joleen H. Blok (EUR: Erasmus University Rotterdam)H-Index: 19
#2Annemieke Ruitenberg (EUR: Erasmus University Rotterdam)H-Index: 17
Last.Gerhard H. Visser (EUR: Erasmus University Rotterdam)H-Index: 17
view all 3 authors...
Source
#1Annemieke Ruitenberg (EUR: Erasmus University Rotterdam)H-Index: 17
#2Tom den Heijer (EUR: Erasmus University Rotterdam)H-Index: 19
Last.Monique M.B. Breteler (EUR: Erasmus University Rotterdam)H-Index: 142
view all 7 authors...
Cerebral blood flow (CBF) velocity is decreased in patients with Alzheimer's disease. It is being debated whether this reflects diminished demand because of advanced neurodegeneration or that cerebral hypoperfusion contributes to dementia. We examined the relation of CBF velocity as measured with transcranial Doppler with dementia and markers of incipient dementia (ie, cognitive decline and hippocampal and amygdalar atrophy on magnetic resonance imaging) in 1,730 participants of the Rotterdam St...
445 CitationsSource
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