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Carlos Alberto Rodríguez-Romero
National University of Colombia
EconomicsPediatricsAsthmaPopulationMedicine
155Publications
16H-index
1,139Citations
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Publications 146
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#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Monica P. Sossa-Briceño (National University of Colombia)H-Index: 7
view all 3 authors...
Objective. Although valved spacers are the preferred method for administering metered-dose inhaler bronchodilators such as albuterol in pediatric acute asthma, their high cost and their lack of availability have limited their use, especially in low- and middle-income countries (LMICs). Because of this, it is a common practice to use home-made spacers, although a formal analysis evaluating their cost-effectiveness is lacking. Therefore, the objective of this study was to analyze the cost-effectiv...
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#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Ricardo M. Fernandes (IMM: Instituto de Medicina Molecular)H-Index: 20
Last. Rafael Leite Pacheco (UNIFESP: Federal University of São Paulo)H-Index: 3
view all 5 authors...
: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a serious threat to public health and local economies around the globe. This has created an urgent need to identify effective medications for its prevention and treatment (1). Among these treatments, the off-label use of hydroxychloroquine (HCQ), a less toxic derivate of chloroquine, has become a common practice among clinicians, including pediatricians, despite lack of evidence of its clinical efficacy for t...
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#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Monica P. Sossa-Briceño (National University of Colombia)H-Index: 7
Last. Jose A. Castro-Rodriguez (UC: Pontifical Catholic University of Chile)H-Index: 34
view all 3 authors...
OBJECTIVES: Although a short course (ie, 3 to 5 days) of orally administered prednisolone is a common and widely accepted practice among clinicians for administering systemic corticosteroids in pediatric acute asthma, oral dexamethasone for 1 to 2 days is an attractive alternative to prednisolone due to its better palatability and compliance. However, a cost-effectiveness analysis regarding the use of dexamethasone compared to prednisolone is not sufficient, especially in lower- and middle-incom...
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#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Monica P. Sossa-Briceño (National University of Colombia)H-Index: 7
Last. Jose A. Castro-Rodriguez (UC: Pontifical Catholic University of Chile)H-Index: 34
view all 3 authors...
OBJECTIVES: There has been no systematic review of studies aimed to predict differential responses to medication regimens for asthma controller therapies in pediatric patients. The aim of the present study was to summarize those identifying biomarkers for the different asthma controller therapies. METHODS: Studies published by June 2019 that report phenotypic or genotypic characteristics or biomarkers that could potentially serve as response predictors to asthma controller therapies in pediatric...
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#1Sol Maria Piña-Hincapie (National University of Colombia)
#2Monica P. Sossa-Briceño (National University of Colombia)H-Index: 7
Last. Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
view all 3 authors...
Abstract Introduction and Objectives Despite the recommendation against routine use of inhaled bronchodilators in infants with viral bronchiolitis given in the main clinical practice guidelines (CPGs) on viral bronchiolitis, albuterol is widely prescribed to patients with this disease. The aim of this study was to identify predictors of prescription of albuterol in a population of infants hospitalized for viral bronchiolitis. Material and Methods An analytical cross-sectional study performed dur...
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#1Maria Arroyo (Children's National Medical Center)H-Index: 1
#2Kyle Salka (Children's National Medical Center)H-Index: 3
Last. Gustavo Nino (Children's National Medical Center)H-Index: 8
view all 7 authors...
Introduction: Viral bronchiolitis is a term often used to group all infants with the first episode of severe viral respiratory infection. However, this term encompasses a collection of different clinical and biological processes. We hypothesized that the first episode of severe viral respiratory infection in infants can be subset into clinical phenotypes with distinct outcomes and underlying airway disease patterns. Methods: We included children (≤2 years old) hospitalized for the first time due...
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#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Jose A. Castro-Rodriguez (UC: Pontifical Catholic University of Chile)H-Index: 34
Last. Fabio Midulla (Sapienza University of Rome)H-Index: 30
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Summary Although recent guidelines recommend a minimalist approach to bronchiolitis, there are several issues with this posture. First, there are concerns about the definition of the disease, the quality of the guidelines, the method of administration of bronchodilators, and the availability of tools to evaluate the response to therapies. Second, for decades it has been assumed that all cases of viral bronchiolitis are the same, but recent evidence has shown that this is not the case. Distinct b...
2 CitationsSource
#1Carlos Alberto Rodríguez-Romero (National University of Colombia)H-Index: 16
#2Monica P. Sossa-Briceño (National University of Colombia)H-Index: 7
Last. Jose A. Castro-Rodriguez (UC: Pontifical Catholic University of Chile)H-Index: 34
view all 3 authors...
Abstract Introduction and objectives With the aim of making informed decisions on resource allocation, there is a critical need for studies that provide accurate information on hospital costs for treating pediatric asthma exacerbations, mainly in middle-income countries (MICs). The aim of the present study was to evaluate the direct medical costs associated with pediatric asthma exacerbations requiring hospital attendance in Bogota, Colombia. Patients and methods We reviewed the available electr...
2 CitationsSource
#1Maria Arroyo (Children's National Medical Center)H-Index: 1
#2Kyle Salka (Children's National Medical Center)H-Index: 3
Last. Gustavo NinoH-Index: 12
view all 6 authors...
Infants requiring hospitalization due to a viral lower respiratory tract infection (LRTI) have a high risk of developing recurrent respiratory illnesses in early life and asthma beyond childhood. Notably, all validated clinical scales for viral LRTI have focused on predicting acute severity instead of recurrence. We present a novel clinical approach combining individual risk factors with bedside clinical parameters to predict recurrence after viral LRTI hospitalization in young children. A retro...
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#1Gustavo Nino (GW: George Washington University)H-Index: 8
#2Awais Mansoor (Children's National Medical Center)H-Index: 10
Last. Marius George LinguraruH-Index: 11
view all 12 authors...
We need a better risk stratification system for the increasing number of survivors of extreme prematurity suffering the most severe forms of bronchopulmonary dysplasia (BPD). However, there is still a paucity of studies providing scientific evidence to guide future updates of BPD severity definitions. Our goal was to validate a new predictive model for BPD severity that incorporates respiratory assessments beyond 36 weeks postmenstrual age (PMA). We hypothesized that this approach improves BPD r...
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