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Arjen E. van’t Hof
University of Liverpool
GeneGenomeGeneticsLocus (genetics)Biology
16Publications
6H-index
441Citations
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Publications 15
Newest
#1Ilik J. Saccheri (University of Liverpool)H-Index: 27
#2Samuel Whiteford (University of Liverpool)
Last. Arjen E. van’t Hof (University of Liverpool)H-Index: 6
view all 4 authors...
Sex chromosomes are predicted to harbour elevated levels of sexually antagonistic variation due to asymmetries in the heritability of recessive traits in the homogametic versus heterogametic sex. This evolutionary dynamic may manifest as high recessive load specifically affecting the homogametic sex, and the retention of haplotype diversity in small populations. We tested the hypothesis that the Z chromosome in the butterfly Bicyclus anynana carries a high inbred load for male fertility and viab...
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#1Samuel Whiteford (University of Liverpool)
#2Arjen E. van’t Hof (University of Liverpool)H-Index: 6
Last. Alistair C. Darby (University of Liverpool)H-Index: 33
view all 9 authors...
Background: Recent advances in genomics have addressed the challenge that divergent haplotypes pose to the reconstruction of haploid genomes. However for many organisms, the sequencing of either field-caught individuals or a pool of heterogeneous individuals is still the only practical option. Here we present methodological approaches to achieve three outcomes from pooled long read sequencing: the generation of a contiguous haploid reference sequence, the sequences of heterozygous haplotypes; an...
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#1Arjen E. van’t Hof (University of Liverpool)H-Index: 6
#1Van't Hof Ae (University of Liverpool)H-Index: 1
Last. Ilik J. Saccheri (University of Liverpool)H-Index: 27
view all 5 authors...
The rise of dark (melanic) forms of many species of moth in heavily coal-polluted areas of nineteenth- and twentieth-century Britain, and their post-1970s fall, point to a common selective pressure...
3 CitationsSource
#2Louise A. ReynoldsH-Index: 2
Last. Ilik J. SaccheriH-Index: 27
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#1Amy Eacock (University of Liverpool)H-Index: 1
#2Hannah M. Rowland (University of Cambridge)H-Index: 17
Last. Ilik J. Saccheri (University of Liverpool)H-Index: 27
view all 6 authors...
Light sensing by tissues distinct from the eye occurs in diverse animal groups, enabling circadian control and phototactic behaviour. Extraocular photoreceptors may also facilitate rapid colour change in cephalopods and lizards, but little is known about the sensory system that mediates slow colour change in arthropods. We previously reported that slow colour change in twig-mimicking caterpillars of the peppered moth (Biston betularia) is a response to achromatic and chromatic visual cues. Here ...
1 CitationsSource
#1Joe Turner (University of Liverpool)H-Index: 2
#2Ritesh Krishna (University of Liverpool)H-Index: 10
Last. Alistair C. Darby (University of Liverpool)H-Index: 33
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Background Aedes aegypti is the principal vector of several important arboviruses. Among the methods of vector control to limit transmission of disease are genetic strategies that involve the release of sterile or genetically modified non-biting males, which has generated interest in manipulating mosquito sex ratios. Sex determination in Ae. aegypti is controlled by a non-recombining Y chromosome-like region called the M locus, yet characterisation of this locus has been thwarted by the repetiti...
1 CitationsSource
#1Reuben W. Nowell (Edin.: University of Edinburgh)H-Index: 7
#2Benjamin Elsworth (Edin.: University of Edinburgh)H-Index: 11
Last. Mark Blaxter (Edin.: University of Edinburgh)H-Index: 80
view all 16 authors...
The mycalesine butterfly Bicyclus anynana, the “Squinting bush brown,” is a model organism in the study of lepidopteran ecology, development, and evolution. Here, we present a draft genome sequence for B. anynana to serve as a genomics resource for current and future studies of this important model species. Seven libraries with insert sizes ranging from 350 bp to 20 kb were constructed using DNA from an inbred female and sequenced using both Illumina and PacBio technology; 128 Gb of raw Illumina...
27 CitationsSource
#1L. Basten Snoek (WUR: Wageningen University and Research Centre)H-Index: 26
#2Mark G. Sterken (WUR: Wageningen University and Research Centre)H-Index: 14
Last. Jan E. Kammenga (WUR: Wageningen University and Research Centre)H-Index: 37
view all 9 authors...
Abstract Background Cryptic genetic variation (CGV) is the hidden genetic variation that can be unlocked by perturbing normal conditions. CGV can drive the emergence of novel complex phenotypes through changes in gene expression. Although our theoretical understanding of CGV has thoroughly increased over the past decade, insight into polymorphic gene expression regulation underlying CGV is scarce. Here we investigated the transcriptional architecture of CGV in response to rapid temperature chang...
92 CitationsSource
#1Joe Turner (University of Liverpool)H-Index: 2
#2Ritesh Krishna (IBM)H-Index: 10
Last. Alistair C. Darby (University of Liverpool)H-Index: 33
view all 6 authors...
Aedes aegypti is the principal vector of several important arboviruses. Among the methods of vector control to limit transmission of disease are genetic strategies that involve the release of sterile or genetically modified non-biting males, which has generated interest in manipulating mosquito sex ratios. Sex determination in Ae. aegypti is controlled by a non-recombining Y chromosome-like region called the M locus, yet characterisation of this locus has been thwarted by the repetitive nature o...
1 CitationsSource
#1Arjen E. van’t Hof (University of Liverpool)H-Index: 6
#2Pascal Campagne (University of Liverpool)H-Index: 11
Last. Ilik J. Saccheri (University of Liverpool)H-Index: 27
view all 9 authors...
The mutation responsible for the black carbonaria morph of the peppered moth is identified as a transposable element within the cortex gene.
161 CitationsSource
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