Vincenzo Muto
University of Liège
PsychologyNeuroscienceNon-rapid eye movement sleepWakefulnessNeuroscience of sleep
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Publications 80
#1Maxime Van Egroo (University of Liège)H-Index: 2
#2Daphné Chylinski (University of Liège)H-Index: 2
Last. Fabienne Collette (University of Liège)H-Index: 48
view all 15 authors...
#1Daphné Chylinski (University of Liège)H-Index: 2
#2Franziska RudzikH-Index: 8
Last. Christophe PhillipsH-Index: 54
view all 13 authors...
Arousals during sleep are transient accelerations of the EEG signal, considered to reflect sleep perturbations associated with poorer sleep quality. They are typically detected by visual inspection, which is time consuming, subjective, and prevents good comparability across scorers, studies and research centres. We developed a fully automatic algorithm which aims at detecting artefact and arousal events in whole-night EEG recordings, based on time-frequency analysis with adapted thresholds deriv...
#1Vincenzo Muto (University of Liège)H-Index: 11
#2Ekaterina Koshmanova (University of Liège)
Last. Marie BrandewinderH-Index: 2
view all 28 authors...
A bidirectional detrimental relationship between sleep alteration and Alzheimer9s disease (AD) has been reported in cognitively normal older adults. Here, we tested whether a similar association could be detected in young adults, decades before typical AD symptom onset. We investigated associations between sleep endophenotypes and genome-wide Polygenic Risk Scores (PRS) for AD in 363 young men (22.1 +/- 2.7y) devoid of sleep and cognitive disorders. AD PRS was associated with higher slow wave en...
#2Vincenzo Muto (University of Liège)H-Index: 11
Last. Christophe Phillips (University of Liège)H-Index: 54
view all 18 authors...
Sleep studies face new challenges in terms of data, objectives and metrics. This requires reappraising the adequacy of existing analysis methods, including scoring methods. Visual and automatic sleep scoring of healthy individuals were compared in terms of reliability (i.e., accuracy and stability) to find a scoring method capable of giving access to the actual data variability without adding exogenous variability. A first dataset (DS1, four recordings) scored by six experts plus an autoscoring ...
1 CitationsSource
#1Maxime Van Egroo (University of Liège)H-Index: 2
#2Justinas Narbutas (University of Liège)H-Index: 2
Last. Gilles Vandewalle (University of Liège)H-Index: 38
view all 22 authors...
Age-related cognitive decline arises from alterations in brain structure as well as in sleep-wake regulation. Here, we investigated whether preserved wake-dependent regulation of cortical function could represent a positive factor for cognitive fitness in aging. We quantified cortical excitability dynamics during prolonged wakefulness as a sensitive marker of age-related alteration in sleep-wake regulation in 60 healthy older individuals (50–69 y; 42 women). Brain structural integrity was assess...
2 CitationsSource
#1Giulia Gaggioni (University of Liège)H-Index: 6
#2Julien Q. M. Ly (University of Liège)H-Index: 4
Last. Gilles Vandewalle (University of Liège)H-Index: 38
view all 19 authors...
Abstract Cortical excitability depends on sleep-wake regulation, is central to cognition, and has been implicated in age-related cognitive decline. The dynamics of cortical excitability during prolonged wakefulness in aging are unknown, however. Here, we repeatedly probed cortical excitability of the frontal cortex using transcranial magnetic stimulation and electroencephalography in 13 young and 12 older healthy participants during sleep deprivation. Although overall cortical excitability did n...
6 CitationsSource
#1Justinas Narbutas (University of Liège)H-Index: 2
#2Maxime Van Egroo (University of Liège)H-Index: 2
Last. Fabienne Collette (University of Liège)H-Index: 48
view all 17 authors...
#1Gilles Vandewalle (University of Liège)H-Index: 38
#2Vincenzo Muto (University of Liège)H-Index: 11
Last. Christina Schmidt (University of Liège)H-Index: 23
view all 3 authors...
#1Vincenzo Muto (University of Liège)H-Index: 11
Last. Pierre Maquet (University of Liège)H-Index: 80
view all 17 authors...
Abstract Study Objectives New challenges in sleep science require to describe fine grain phenomena or to deal with large datasets. Beside the human resource challenge of scoring huge datasets, the inter- and intra-expert variability may also reduce the sensitivity of such studies. Searching for a way to disentangle the variability induced by the scoring method from the actual variability in the data, visual and automatic sleep scorings of healthy individuals were examined. Methods A first datase...
#1Mathilde Reyt (University of Liège)
#2Alizée Latteur (University of Liège)
Last. Grégory Hammad (University of Liège)
view all 5 authors...
Objectif La fragmentation du cycle veille-sommeil augmente avec l’âge. Ici, nous explorons la sieste comme indicateur de cette fragmentation et son impact sur les performances cognitives. Methodes Des donnees d’actimetrie ont ete collectees chez 35 personnes âgees (57–85 ans, 18 femmes, 19 siesteurs [sieste > 20 min/jour, > 3 fois/semaine, depuis > 1 an]). La fragmentation du sommeil a ete evaluee grâce a la probabilite de transition d’une periode de repos vers une periode d’activite (kRA). Pour...