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Daniel Broszczak
Australian Catholic University
23Publications
4H-index
58Citations
Publications 23
Newest
Published on Dec 17, 2018in Journal of Proteome Research 3.78
Tuo Zang2
Estimated H-index: 2
(QUT: Queensland University of Technology),
Leila Cuttle26
Estimated H-index: 26
(QUT: Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(QUT: Queensland University of Technology)
Blister fluid (BF) is a novel and viable research matrix for burn injury study, which can reflect both systemic and local microenvironmental responses. The protein abundance in BF from different burn severities were initially observed using a 2D SDS-PAGE approach. Subsequently, a quantitative data independent acquisition (DIA) method, SWATH, was employed to characterize the proteome of pediatric burn blister fluid. More than 600 proteins were quantitatively profiled in 87 BF samples from differe...
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Published on Jan 1, 2018
Jonathan Peake33
Estimated H-index: 33
,
Lian Liu + 1 AuthorsDaniel Broszczak4
Estimated H-index: 4
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Published on Feb 1, 2017
Daniel Broszczak4
Estimated H-index: 4
,
Elizabeth Sydes1
Estimated H-index: 1
+ 1 AuthorsTony J. Parker6
Estimated H-index: 6
Chronic wounds, in particular venous leg ulcers (VLU), represent a substantial burden for economies, healthcare systems and societies worldwide. This burden is exacerbated by the recalcitrant nature of these wounds, despite best practice, evidence-based care, which substantially reduces the quality of life of patients. Furthermore, co-morbidities such as diabetes and cardiovascular disease within ageing populations further contribute to the increasing prevalence in developed countries. This revi...
1 Citations
Published on Sep 1, 2016in Journal of Proteomics 3.54
Tuo Zang2
Estimated H-index: 2
(QUT: Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(QUT: Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(QUT: Queensland University of Technology)
Abstract Burn injury is highly traumatic for paediatric patients, with the severity of the burn often dictating the extent of scar formation. The diagnosis of burn wound severity is largely determined by the attending clinician's experience. Thus, a greater understanding of the biochemistry at burn wound site environment and the biology of burns of different severities at an earlier stage may reduce the reliance on subjective diagnoses. In this study, blister fluid was collected from superficial...
3 Citations Source Cite
Published on Apr 2, 2016in Expert Review of Proteomics 2.96
James A. Broadbent7
Estimated H-index: 7
(QUT: Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(QUT: Queensland University of Technology)
+ 1 AuthorsFlavia Huygens23
Estimated H-index: 23
(QUT: Queensland University of Technology)
ABSTRACTThe comparison of proteomes between genetically heterogeneous bacterial strains may offer valuable insights into physiological diversity and function, particularly where such variation aids in the survival and virulence of clinically-relevant strains. However, reports of such comparisons frequently fail to account for underlying genetic variance. As a consequence, the current knowledge regarding bacterial physiological diversity at the protein level may be incomplete or inaccurate. To ad...
5 Citations Source Cite
Published on Jan 2, 2016in Expert Review of Proteomics 2.96
Tuo Zang2
Estimated H-index: 2
(QUT: Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(QUT: Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(QUT: Queensland University of Technology)
Burn injury is a prevalent and traumatic event for pediatric patients. At present, the diagnosis of burn injury severity is subjective and lacks a clinically relevant quantitative measure. This is due in part to a lack of knowledge surrounding the biochemistry of burn injuries and that of blister fluid. A more complete understanding of the blister fluid biochemistry may open new avenues for diagnostic and prognostic development. Burn insult induces a highly complex network of signaling processes...
4 Citations Source Cite
Published on Jan 1, 2016
Tuo Zang2
Estimated H-index: 2
,
Daniel Broszczak4
Estimated H-index: 4
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
Burn injury is a prevalent and traumatic event for pediatric patients. At present, the diagnosis of burn injury severity is subjective and lacks a clinically relevant quantitative measure. This is due in part to a lack of knowledge surrounding the biochemistry of burn injuries and that of blister fluid. A more complete understanding of the blister fluid biochemistry may open new avenues for diagnostic and prognostic development. Burn insult induces a highly complex network of signaling processes...
Christina Parker6
Estimated H-index: 6
,
Daniel Broszczak4
Estimated H-index: 4
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
Free to read The highly complex disorder of chronic wounds is a significant problem. Information is often lacking, dynamically changing, or contradictory and thus acts to impede the progression of research and its translation into clinical care. Transdisciplinary collaboration may play an important role in chronic wound research, permitting key stakeholders with a single, central goal to take a unified approach towards addressing the problem. While transdisciplinary collaboration is not a new co...
Published on Mar 1, 2015in Advances in wound care
Tony J. Parker6
Estimated H-index: 6
(QUT: Queensland University of Technology),
James A. Broadbent7
Estimated H-index: 7
+ 3 AuthorsZee Upton31
Estimated H-index: 31
Significance: Chronic wounds represent a major burden on global healthcare systems and reduce the quality of life of those affected. Significant advances have been made in our understanding of the biochemistry of wound healing progression. However, knowledge regarding the specific molecular processes influencing chronic wound formation and persistence remains limited. Recent Advances: Generally, healing of acute wounds begins with hemostasis and the deposition of a plasma-derived provisional mat...
1 Citations Source Cite
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