Daniel Broszczak
Australian Catholic University
23Publications
4H-index
57Citations
Publications 23
Newest
Published on Dec 17, 2018in Journal of Proteome Research 3.95
Tuo Zang2
Estimated H-index: 2
(Queensland University of Technology),
Leila Cuttle25
Estimated H-index: 25
(Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(Queensland University of Technology)
Blister fluid (BF) is a novel and viable research matrix for burn injury study, which can reflect both systemic and local microenvironmental responses. The protein abundance in BF from different burn severities were initially observed using a 2D SDS-PAGE approach. Subsequently, a quantitative data independent acquisition (DIA) method, SWATH, was employed to characterize the proteome of pediatric burn blister fluid. More than 600 proteins were quantitatively profiled in 87 BF samples from differe...
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Published on Apr 2, 2016in Expert Review of Proteomics 3.49
James A. Broadbent6
Estimated H-index: 6
(Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(Queensland University of Technology)
+ 1 AuthorsFlavia Huygens23
Estimated H-index: 23
(Queensland University of Technology)
ABSTRACTThe comparison of proteomes between genetically heterogeneous bacterial strains may offer valuable insights into physiological diversity and function, particularly where such variation aids in the survival and virulence of clinically-relevant strains. However, reports of such comparisons frequently fail to account for underlying genetic variance. As a consequence, the current knowledge regarding bacterial physiological diversity at the protein level may be incomplete or inaccurate. To ad...
4 Citations Source Cite
Published on Sep 1, 2016in Journal of Proteomics 3.72
Tuo Zang2
Estimated H-index: 2
(Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(Queensland University of Technology)
Abstract Burn injury is highly traumatic for paediatric patients, with the severity of the burn often dictating the extent of scar formation. The diagnosis of burn wound severity is largely determined by the attending clinician's experience. Thus, a greater understanding of the biochemistry at burn wound site environment and the biology of burns of different severities at an earlier stage may reduce the reliance on subjective diagnoses. In this study, blister fluid was collected from superficial...
3 Citations Source Cite
Published on Sep 1, 2016in Data in Brief
Tuo Zang2
Estimated H-index: 2
(Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(Queensland University of Technology)
The data presented here are associated with the article “The blister fluid proteome of paediatric burns” (Zang et al., 2016) [1]. Burn injury is a highly traumatic event for children. The degree of burn severity (superficial-, deep-, or full-thickness injury) often dictates the extent of later scar formation which may require long term surgical operation or skin grafting. The data were obtained by fractionating paediatric burn blister fluid samples, which were pooled according to burn depth and ...
2 Citations Source Cite
Published on Jan 2, 2016in Expert Review of Proteomics 3.49
Tuo Zang2
Estimated H-index: 2
(Queensland University of Technology),
Daniel Broszczak4
Estimated H-index: 4
(Queensland University of Technology)
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
(Queensland University of Technology)
Burn injury is a prevalent and traumatic event for pediatric patients. At present, the diagnosis of burn injury severity is subjective and lacks a clinically relevant quantitative measure. This is due in part to a lack of knowledge surrounding the biochemistry of burn injuries and that of blister fluid. A more complete understanding of the blister fluid biochemistry may open new avenues for diagnostic and prognostic development. Burn insult induces a highly complex network of signaling processes...
4 Citations Source Cite
Published on May 1, 2015in International Journal of Medical Microbiology 3.30
James A. Broadbent6
Estimated H-index: 6
(Queensland University of Technology),
Dayle L. Sampson3
Estimated H-index: 3
(Queensland University of Technology)
+ 2 AuthorsFlavia Huygens23
Estimated H-index: 23
(Queensland University of Technology)
Abstract Staphylococcus aureus ( S. aureus ) is a prominent human and livestock pathogen investigated widely using omic technologies. Critically, due to availability, low visibility or scattered resources, robust network and statistical contextualisation of the resulting data is generally under-represented. Here, we present novel meta-analyses of freely-accessible molecular network and gene ontology annotation information resources for S. aureus omics data interpretation. Furthermore, through th...
1 Citations Source Cite
Christina Parker5
Estimated H-index: 5
,
Daniel Broszczak4
Estimated H-index: 4
+ 3 AuthorsTony J. Parker6
Estimated H-index: 6
Free to read The highly complex disorder of chronic wounds is a significant problem. Information is often lacking, dynamically changing, or contradictory and thus acts to impede the progression of research and its translation into clinical care. Transdisciplinary collaboration may play an important role in chronic wound research, permitting key stakeholders with a single, central goal to take a unified approach towards addressing the problem. While transdisciplinary collaboration is not a new co...
Published on Mar 1, 2015in Advances in wound care
Tony J. Parker6
Estimated H-index: 6
(Queensland University of Technology),
James A. Broadbent6
Estimated H-index: 6
+ 3 AuthorsZee Upton29
Estimated H-index: 29
Significance: Chronic wounds represent a major burden on global healthcare systems and reduce the quality of life of those affected. Significant advances have been made in our understanding of the biochemistry of wound healing progression. However, knowledge regarding the specific molecular processes influencing chronic wound formation and persistence remains limited. Recent Advances: Generally, healing of acute wounds begins with hemostasis and the deposition of a plasma-derived provisional mat...
1 Citations Source Cite
Published on Mar 23, 2012in PLOS ONE 2.77
Tony J. Parker6
Estimated H-index: 6
(Queensland University of Technology),
Dayle L. Sampson3
Estimated H-index: 3
(Queensland University of Technology)
+ 5 AuthorsZee Upton29
Estimated H-index: 29
(Queensland University of Technology)
Biomarker analysis has been implemented in sports research in an attempt to monitor the effects of exertion and fatigue in athletes. This study proposed that while such biomarkers may be useful for monitoring injury risk in workers, proteomic approaches might also be utilised to identify novel exertion or injury markers. We found that urinary urea and cortisol levels were significantly elevated in mining workers following a 12 hour overnight shift. These levels failed to return to baseline over ...
10 Citations Source Cite
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