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José Adélaïde
French Institute of Health and Medical Research
139Publications
49H-index
7,594Citations
Publications 139
Newest
#1Frédéric Courtier (AMU: Aix-Marseille University)H-Index: 2
#2Séverine Garnier (French Institute of Health and Medical Research)H-Index: 2
Last.Norbert Vey (AMU: Aix-Marseille University)H-Index: 49
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#2Pascal FinettiH-Index: 42
Last.François BertucciH-Index: 53
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Triple negative breast cancer (TNBC) represent 15% of breast cancers. Histoclinical features and marketed prognostic gene expression signatures (GES) failed to identify good- and poor-prognosis patients. Tyrosine kinases (TK) represent potential prognostic and/or therapeutic targets for TNBC. We sought to define a prognostic TK GES in a large series of TNBC. mRNA expression and histoclinical data of 6379 early BCs were collected from 16 datasets. We searched for a TK-based GES associated with di...
#1C. Vicier (AMU: Aix-Marseille University)H-Index: 2
#2Nicolas IsambertH-Index: 25
Last.Arnaud Guille (French Institute of Health and Medical Research)H-Index: 9
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1091Background: Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)-pathway is frequently activated in HER2-negative breast cancer and may play a role in taxane-resistance...
#1Marguerite TyranH-Index: 2
#2Nadine CarbucciaH-Index: 22
Last.A. TalletH-Index: 12
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Improving the systemic treatment of brain metastases (BM) in primary breast cancer (PBC) is impaired by the lack of genomic characterization of BM. To estimate the concordance of DNA copy-number-alterations (CNAs), mutations, and actionable genetic alterations (AGAs) between paired samples, we performed whole-genome array-comparative-genomic-hybridization, and targeted-next-generation-sequencing on 14 clinical PBC–BM pairs. We found more CNAs, more mutations, and higher tumor mutational burden, ...
#1Anne Wanquet (AMU: Aix-Marseille University)H-Index: 4
#2Frédéric Courtier (AMU: Aix-Marseille University)H-Index: 2
Last.Norbert Vey (AMU: Aix-Marseille University)H-Index: 49
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#1Renaud Sabatier (French Institute of Health and Medical Research)H-Index: 11
#2Marc Lopez (French Institute of Health and Medical Research)H-Index: 31
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#1Luc Xerri (AMU: Aix-Marseille University)H-Index: 40
#2José Adélaïde (French Institute of Health and Medical Research)H-Index: 49
Last.Anne MuratiH-Index: 22
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