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Michael Dray
Waikato Hospital
EndocrinologyPathologyHypophosphatasiaMedicineBiology
25Publications
7H-index
135Citations
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Publications 26
Newest
#1Rita Upreti (Waikato Hospital)
#2Michael Dray (Waikato Hospital)H-Index: 7
Last. Marianne S. Elston (University of Auckland)H-Index: 13
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Hyperprolactinemia in premenopausal women often presents with amenorrhea, symptoms of estrogen deficiency and sub-fertility. After exclusion of other common causes and in the context of a normal pituitary MRI scan, hyperprolactinemia is typically deemed “idiopathic.” Here we present a case where excess prolactin secretion was attributed to a uterine fibroid and following myomectomy the hyperprolactinemia and its clinical sequelae resolved. Following 6 years of secondary infertility, a 41-year-ol...
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#2Michael Dray (Waikato Hospital)H-Index: 7
Last. Tim Cundy (University of Auckland)H-Index: 48
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Adults with hypophosphatasia (HPP) may suffer femoral fractures resembling the atypical femoral fractures that can occur with long‐term bisphosphonate treatment, and there is an emerging consensus that bisphosphonates should not be used in adults with HPP and low bone mass. However, the spectrum of HPP in adults is wide: ranging from the severely affected—who commonly have osteomalacia—through to the minimally affected. The former typically have biallelic and the latter, heterozygous ALPL mutati...
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#1Mark Zhu (University of Auckland)H-Index: 8
#2Mei Lin Tay (University of Auckland)H-Index: 2
Last. David Musson (University of Auckland)H-Index: 7
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Background Augmenting repairs with extracellular matrix–based scaffolds is a common option for rotator cuff tears. In this study, a new collagen scaffold was assessed for its efficacy in augmenting rotator cuff repair. Methods The collagen scaffold was assessed in vitro for cytocompatibility and retention of tenocyte phenotype using alamarBlue assays, fluorescent imaging, and real-time polymerase chain reaction. Immunogenicity was assessed in vitro by the activation of human monocytes. In vivo, ...
1 CitationsSource
#1Tim CundyH-Index: 48
#2Michael DrayH-Index: 7
Last. Peter H. ByersH-Index: 70
view all 18 authors...
Source
#1Tim CundyH-Index: 48
#2Michael DrayH-Index: 7
Last. Peter H. ByersH-Index: 70
view all 18 authors...
Osteogenesis imperfecta (OI) is a genetic bone disorder characterized by fractures, low bone mass, and skeletal fragility. It most commonly arises from dominantly inherited mutations in the genes COL1A1 and COL1A2 that encode the chains of type I collagen. A number of recent reports have suggested that mutations affecting the carboxyl-terminal propeptide cleavage site in the products of either COL1A1 or COL1A2 give rise to a form of OI characterized by unusually dense bones. We have assembled cl...
6 CitationsSource
#1Ashika Chhana (University of Auckland)H-Index: 9
#2Anthony Doyle (University of Auckland)H-Index: 24
Last. Nicola Dalbeth (University of Auckland)H-Index: 6
view all 9 authors...
Dual-energy CT (DECT) and MRI are advanced imaging methods used to visualise gout pathology. DECT can identify monosodium urate (MSU) crystals in people with gout,1 ,2 and also has conventional CT properties, allowing assessment of tophus and bone pathology.3 ,4 MRI is used to assess inflammation, bone erosion and cartilage damage in gout.5–7 This study aimed to compare DECT and MRI with corresponding anatomical pathology in the assessment of gout. Cadaveric joint specimens were obtained from tw...
6 CitationsSource
#1Ryan Gao (University of Auckland)H-Index: 2
#2Maureen Watson (University of Auckland)H-Index: 17
Last. David Musson (University of Auckland)H-Index: 7
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Lactoferrin is a multifunctional glycoprotein with therapeutic potential for bone tissue engineering. The aim of this study was to assess the efficacy of local application of lactoferrin on bone regeneration. Five-millimetre critical-sized defects were created over the right parietal bone in 64 Sprague–Dawley rats. The rats were randomized into four groups: group 1 (n = 20) had empty defects; group 2 (n = 20) had defects grafted with collagen gels (3 mg/ml); group 3 (n = 20) had defects grafted ...
7 CitationsSource
#1Marianne S. Elston (Waikato Hospital)H-Index: 13
#2Veronica CrawfordH-Index: 2
Last. John V. Conaglen (University of Auckland)H-Index: 18
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2 CitationsSource
#1Marianne S. Elston (University of Auckland)H-Index: 13
#2Shekhar Sehgal (Waikato Hospital)H-Index: 3
Last. Anthony J. Gill (Kolling Institute of Medical Research)H-Index: 50
view all 7 authors...
2 CitationsSource
#1Ashika ChhanaH-Index: 9
#2Anthony DoyleH-Index: 24
Last. Nicola DalbethH-Index: 45
view all 9 authors...
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