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Yvan Vandenplas
Vrije Universiteit Brussel
586Publications
52H-index
11kCitations
Publications 586
Newest
#1Harm WopereisH-Index: 8
Last.Neil Shah (GOSH: Great Ormond Street Hospital)H-Index: 23
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Background Altered gut microbiota is implicated in cow’s milk allergy (CMA) and differs markedly from healthy, breastfed infants. Infants who suffer from severe CMA often rely on cow’s milk protein avoidance and, when breastfeeding is not possible, on specialised infant formulas such as amino-acid based formulas (AAF). Herein, we report the effects of an AAF including specific synbiotics on oral and gastrointestinal microbiota of infants with non-IgE mediated CMA with reference to healthy, breas...
#1Adam T. FoxH-Index: 16
#2Harm Wopereis (WUR: Wageningen University and Research Centre)H-Index: 8
Last.Christina E. West (Umeå University)H-Index: 19
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Background Here we report follow-up data from a double-blind, randomized, controlled multicenter trial, which investigated fecal microbiota changes with a new amino acid-based formula (AAF) including synbiotics in infants with non-immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA).
#1Celine Perceval (Vrije Universiteit Brussel)
#2Hania Szajewska (Medical University of Warsaw)H-Index: 64
Last.Yvan Vandenplas (Vrije Universiteit Brussel)H-Index: 52
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Summary The gastrointestinal microbiome is a hot topic in clinical research. Beneficial effects of selected probiotics in the prevention of gastrointestinal disorders are mainly restricted to acute gastroenteritis, antibiotic-associated diarrhoea, infantile colic, and necrotising enterocolitis. However, no broad consensus exists to recommend the use of probiotics in the prevention of these conditions, mainly because of the different design of the studies done so far, resulting in little evidence...
Last.Yvan VandenplasH-Index: 52
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This is a narrative review, largely of randomized trials on the impacts of probiotics. It concludes that evidence for beneficial effects of selected probiotics in the prevention of gastrointestinal disorders is limited mainly to acute gastroenteritis, antibiotic-associated diarrhea, infantile colic and necrotizing enterocolitis. However, there is no broad consensus to recommend the use of probiotics in the prevention of these conditions, mainly because of the different designs used in different ...
Allergy risk has become a significant public health issue with increasing prevalence. Exclusive breastfeeding is recommended for the first six months of life, but this recommendation is poorly adhered to in many parts of the world, including the Middle-East region, putting infants at risk of developing allergic sensitization and disorders. When breastfeeding is not possible or not adequate, a partially hydrolyzed whey formula (pHF-W) has shown proven benefits of preventing allergy, mainly atopic...
#1Enza D’AuriaH-Index: 3
#2Silvia SalvatoreH-Index: 20
Last.Gian Vincenzo ZuccottiH-Index: 36
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Cow’s milk proteins cause allergic symptoms in 2% to 3% of all infants. In these individuals, the physiological mechanism of tolerance is broken with subsequent possible sensitization to antigens, which can lead eventually to allergic responses. The present review aims to provide an overview of different aspects of immune modulation by dietary intervention in cow’s milk allergy (CMA). It focuses on pathogenetic mechanisms of different CMA related disorders, e.g., gastroesophageal reflux and eosi...
#1Yvan Vandenplas (Vrije Universiteit Brussel)H-Index: 52
#2Zakiudin Munasir (UI: University of Indonesia)H-Index: 4
Last.Deni Krisnamurti (Nestlé)
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OBJECTIVE: In therapeutic trials for infant gastroesophageal reflux disease (GERD), ways to define GERD and measure and report study outcomes vary widely. The aim of this study was to develop a core outcome set (COS) for infant GERD. METHODS: The COS was developed using the Delphi technique, adhering to the Outcome Measures in Rheumatology Initiative 2.0 recommendations. Healthcare professionals (HCPs) (predominantly pediatric gastroenterologists and general pediatricians) and parents of infants...
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