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Alan J. Silman
University of Oxford
Physical therapyRheumatoid arthritisPopulationDiabetes mellitusMedicine
891Publications
124H-index
73kCitations
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Publications 879
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#1Edward Burn (University of Oxford)H-Index: 10
#2Christopher J. Edwards (University of Oxford)H-Index: 42
Last. Daniel Prieto Alhambra (University of Oxford)H-Index: 33
view all 8 authors...
OBJECTIVE: To estimate the lifetime risk of knee and hip replacement following a diagnosis of RA. METHODS: The analysis was undertaken using routinely collected data from the English NHS. Diagnosis of RA was identified using primary care records, with knee and hip replacement observed in linked hospital records. Parametric survival models were fitted for up to 15 years of follow-up, with age, sex, Charlson comorbidity score, socioeconomic status, BMI and smoking status included as explanatory va...
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#1A Prats-UribeH-Index: 4
#2Klara BerencsiH-Index: 10
Last. D Prieto AlhambraH-Index: 2
view all 15 authors...
#1Hessam Soutakbar (University of Oxford)H-Index: 1
#2Sarah E Lamb (University of Oxford)H-Index: 51
Last. Alan J. Silman (University of Oxford)H-Index: 124
view all 3 authors...
Summary Objective To investigate the influence of physical activity on incidence of knee osteoarthritis (OA) in overweight and obese men and women. Design Data were extracted from the Osteoarthritis Initiative cohort on 1,667 participants without symptomatic knee OA at baseline. We used logistic regression and marginal effect models to estimate the effect of body mass index (BMI) and reported physical activity score, together with the interaction between them, on the development of radiographic ...
1 CitationsSource
#1Rory J Ferguson (University of Oxford)H-Index: 2
#2Alan J. Silman (University of Oxford)H-Index: 124
Last. Anne Luebbeke-Wolff (University of Oxford)H-Index: 28
view all 9 authors...
Background and purpose — Data from several joint replacement registries suggest that the rate of early revision surgery after primary total hip arthroplasty (THA) is increasing. The ASA class, now ...
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#1Edward Burn (University of Oxford)H-Index: 10
#2Christopher J. Edwards (University of Oxford)H-Index: 42
Last. Daniel Prieto Alhambra (University of Oxford)H-Index: 33
view all 8 authors...
Background Understanding the lifetime risk of knee and hip replacement following a diagnosis of rheumatoid arthritis (RA) would help provide patients and clinicians with an indication of long-term prognosis and future health care utilisation. Objectives To estimate the lifetime risk of knee and hip replacement following a diagnosis of RA. Methods Routinely collected data from the English NHS was used to inform the analysis. Diagnosis of RA was identified using primary care records, with knee and...
Source
#1Edward Burn (University of Oxford)H-Index: 10
#2Christopher J. Edwards (Wellcome Trust)H-Index: 42
Last. Daniel Prieto Alhambra (University of Oxford)H-Index: 33
view all 8 authors...
OBJECTIVES: To compare outcomes of total knee replacement (TKR) and total hip replacement (THR) for individuals with RA and OA. METHODS: We performed a cohort study using routinely collected data. Oxford Knee Score, Oxford Hip Score, and EuroQol 5-dimension 3-level (EQ-5D-3L) questionnaires were collected before and 6 months after surgery. Multivariable regressions were used to estimate the association between diagnosis and post-operative scores after controlling for pre-operative scores and pat...
1 CitationsSource
#1Edward Burn (University of Oxford)H-Index: 10
Last. Rafael Pinedo-Villanueva (University of Oxford)H-Index: 12
view all 8 authors...
Summary Objective The aim of this study was to assess the association of body mass index (BMI) and smoking with risk of revision following total knee and hip replacement (TKR and THR). Design Primary care data, from the Clinical Practice Research Datalink (CPRD), was linked to inpatient hospital records, from Hospital Episode Statistics Admitted Patient Care (HES APC), and covered 1997 to 2014. Parametric survival models, with BMI and smoking status included as explanatory variables, were estima...
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#1Rory J Ferguson (University of Oxford)H-Index: 2
#2Daniel Prieto Alhambra (University of Oxford)H-Index: 33
Last. Alan J. Silman (University of Oxford)H-Index: 124
view all 11 authors...
PURPOSE: The diagnosis of hip osteoarthritis is subject to several uncertainties, especially in primary care. The aims of this study were to determine (i) the diagnostic accuracy of coding of hip osteoarthritis by primary care physicians in the UK Clinical Practice Research Datalink (CPRD), (ii) the relative influence of radiographic and clinical parameters on diagnostic accuracy, and (iii) the accuracy of the diagnosis date. METHODS: An extract of all patients aged over 65 years, with a Read co...
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#1Alan J. SilmanH-Index: 124
#2G J MacfarlaneH-Index: 8
Last. Tatiana V. MacfarlaneH-Index: 38
view all 3 authors...
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