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Marie-Christine Boutron-Ruault
Université Paris-Saclay
CancerEuropean Prospective Investigation into Cancer and NutritionProspective cohort studyMedicineCohort
598Publications
75H-index
21.5kCitations
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Publications 535
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Purpose: The relationship between egg and cholesterol intakes, and cardiovascular disease is controversial. Meta-analyses indicate that egg consumption is associated with increased cardiovascular disease and mortality, but reduced incidence of hypertension, a major risk factor for cardiovascular disease. This study aims to investigate the associations between consumption of egg and cholesterol, and hypertension risk in a cohort of French women. Methods: We used data from the E3N cohort study, a ...
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#1Jeroen R. Huyghe (Fred Hutchinson Cancer Research Center)H-Index: 16
#2Tabitha A. Harrison (Fred Hutchinson Cancer Research Center)H-Index: 17
Last. Yi Lin (Fred Hutchinson Cancer Research Center)H-Index: 14
view all 141 authors...
Objective An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug candidates for chemoprevention. Known differences in molecular characteristics and environmental risk factors among tumors arising in different locations of the colorectum suggest partly distinct mechanisms of carcinogenesis. The extent to which the cont...
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#1Julia Butt (DKFZ: German Cancer Research Center)H-Index: 9
#2Mazda Jenab (IARC: International Agency for Research on Cancer)H-Index: 66
Last. Tilman Kühn (DKFZ: German Cancer Research Center)H-Index: 28
view all 42 authors...
Background: While Helicobacter pylori (H. pylori) is the major cause of gastric cancer, it has also been suggested to be involved in colorectal cancer (CRC) development. However, prospective studies addressing H. pylori and CRC are sparse and inconclusive. We assessed the association of antibody responses to H. pylori proteins with CRC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We applied H. pylori multiplex serology to measure antibody responses ...
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#1Annika Idahl (Umeå University)H-Index: 22
#2Charlotte Le Cornet (DKFZ: German Cancer Research Center)H-Index: 4
Last. Marina Kvaskoff (Université Paris-Saclay)H-Index: 20
view all 37 authors...
A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic transformation following sexually transmitted infections (STI) and pelvic inflammatory disease. We investigated the hypothesis that past STI infection, particularly Chlamydia trachomatis, is associated with higher EOC risk in a nested case-control study within the European Prospective Investigation into Cancer and...
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#1Julia Mink (Sciences Po)
#2Marie-Christine Boutron-Ruault (French Institute of Health and Medical Research)H-Index: 75
Last. Guy Fagherazzi (French Institute of Health and Medical Research)H-Index: 45
view all 5 authors...
The Developmental Origins of Health and Disease (DOHaD) framework suggests that early-life experiences affect long-term health outcomes. We tested this hypothesis by estimating the long-run effects of exposure to World War II-related food deprivation during childhood and adolescence on the risk of suffering from hypertension and type 2 diabetes at adulthood for 90,226 women from the French prospective cohort study E3N. We found that the experience of food deprivation during early-life was associ...
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#1Raul Zamora-RosH-Index: 36
#2Valerie CayssialsH-Index: 4
Last. Sabina Rinaldi (IARC: International Agency for Research on Cancer)H-Index: 67
view all 38 authors...
Polyphenols are bioactive compounds with several anticarcinogenic activities; however, human data regarding associations with thyroid cancer (TC) is still negligible. Our aim was to evaluate the association between intakes of total, classes and subclasses of polyphenols and risk of differentiated TC and its main subtypes, papillary and follicular, in a European population. The European Prospective Investigation into Cancer and Nutrition cohort included 476,108 men and women from 10 European coun...
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In the present study, the aim was to investigate the correlation between the acute and habitual dietary intake of flavanones, their main food sources and the concentrations of aglycones naringenin and hesperetin in 24 h urine in a European population. A 24-h dietary recall (24-HDR) and a 24-h urine sample were collected the same day from a subsample of 475 people from four different countries of the European Prospective Investigation into Cancer and Nutrition study. Acute and habitual dietary da...
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#1Sabine Naudin (IARC: International Agency for Research on Cancer)H-Index: 1
#2Marta Solans Margalef (University of Girona)
Last. Caroline Besson (Université Paris-Saclay)H-Index: 19
view all 41 authors...
Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) were evaluated in a large-scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases (132 HL and 2,746 NHL) were diagnosed among 453,808 participants after 15 years (median) of follow-...
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#1Elom K. Aglago (IARC: International Agency for Research on Cancer)H-Index: 2
#2Inge Huybrechts (IARC: International Agency for Research on Cancer)H-Index: 48
Last. M. J. Gunter (IARC: International Agency for Research on Cancer)H-Index: 40
view all 47 authors...
Background & Aims There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods Dietary intake of fish (total, fatty/oily, lean/white) and n-3 LC-PUFA were estimated by foo...
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Cutaneous melanoma has been suspected to be influenced by female sex hormones. A review of the literature in 2018 indicated that fertility drug (FD) use was associated with increased melanoma risk among parous women only. However, most studies so far were based on a retrospective design and the current evidence is unclear. We sought to prospectively investigate the associations between FD use and melanoma risk in women. E3N is a prospective cohort of 98 995 French women aged 40-65 years at inclu...
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