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Dominique Cottel
Pasteur Institute
111Publications
33H-index
4,160Citations
Publications 112
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#1Dominique Cottel (Pasteur Institute)H-Index: 33
#2Michèle Montaye (Pasteur Institute)H-Index: 26
Last.Aline Meirhaeghe (Pasteur Institute)H-Index: 36
view all 6 authors...
BackgroundAlthough stroke and acute coronary events share several risk factors, few studies have compared population-level epidemiological surveillance indicators of the two diseases in the same ag...
1 CitationsSource
#1Xavier Hermant (Pasteur Institute)H-Index: 13
#2Charlotte Delay (Pasteur Institute)H-Index: 5
Last.Julie Dumont (Pasteur Institute)H-Index: 20
view all 17 authors...
Background Blood polyunsaturated fatty acid (PUFA) levels are determined by diet and by endogenous synthesis via Δ5- and Δ6-desaturases (encoded by the FADS1 and FADS2 genes, respectively). Genome-wide association studies have reported associations between FADS1-FADS2 polymorphisms and the plasma concentrations of PUFAs, HDL- and LDL-cholesterol, and triglycerides. However, much remains unknown regarding the molecular mechanisms explaining how variants affect the function of FADS1-FADS2 genes. O...
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#1Aline Meirhaeghe (Pasteur Institute)H-Index: 36
#2Dominique Cottel (Pasteur Institute)H-Index: 33
Last.Jean Dallongeville (Pasteur Institute)H-Index: 66
view all 7 authors...
Background Age and sex have a major impact on stroke onset. Aims We aimed to compare the attack, incidence, and 28-day mortality rate for stroke as well as risk factors in men and women aged 35 and over. Methods Data were obtained between 2008 and 2015 from the stroke population-based registry covering the city of Lille (northern France). Results A total of 2426 strokes (1917 incident strokes) were recorded. The number of strokes was lower in women than in men when considering individuals under ...
2 CitationsSource
#1Majid EzzatiH-Index: 107
#2James BenthamH-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
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#1Bin ZhouH-Index: 17
#2James BenthamH-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
view all 841 authors...
22 Citations
#2Ziad AbdeenH-Index: 26
Last.Majid Ezzati (Imperial College London)H-Index: 107
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BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in ...
568 CitationsSource
#1Emilie BérardH-Index: 11
#2V. BongardH-Index: 1
Last.Jean FerrieersH-Index: 72
view all 8 authors...
Source
#1Julie Dumont (Pasteur Institute)H-Index: 20
#2Louisa Goumidi (Pasteur Institute)H-Index: 18
Last.Aline Meirhaeghe (Pasteur Institute)H-Index: 36
view all 14 authors...
Summary Background & aims Blood levels of polyunsaturated fatty acids (PUFAs) are under control of endogenous synthesis via Δ5- and Δ6-desaturases, encoded by the FADS1 and FADS2 genes, respectively and of diet. Genome-wide associations studies (GWAS) reported associations between polymorphisms in FADS1–FADS2 and variations in plasma concentrations of PUFAs, HDL- and LDL-cholesterol and triglycerides. However, it is not established whether dietary PUFAs intake modulates these associations. We as...
6 CitationsSource
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Background In clinical trials, lowering cardiovascular risk factors (RF) reduce cardiovascular (CV) morbidity and mortality. Nonetheless, few data exist on general population. Purpose We assessed theimpact of the control of RF at baseline on long-term all-cause and CV mortality in French general population. Methods Analysis was based on the participants aged 35-64 of the Third French MONICA population-based survey on RF (1995-1996). Vital status was obtained 18 years after inclusion. Statistical...
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