Dominique Cottel
Pasteur Institute
Publications 118
Published on Sep 1, 2018in European Journal of Preventive Cardiology5.64
Dominique Cottel34
Estimated H-index: 34
(Pasteur Institute),
Michèle Montaye27
Estimated H-index: 27
(Pasteur Institute)
+ 3 AuthorsAline Meirhaeghe36
Estimated H-index: 36
(Pasteur Institute)
Published on Sep 1, 2018in Journal of Clinical Lipidology3.58
Xavier Hermant13
Estimated H-index: 13
(Pasteur Institute),
Charlotte Delay5
Estimated H-index: 5
(Pasteur Institute)
+ 14 AuthorsChantal Simon48
Estimated H-index: 48
(French Institute of Health and Medical Research)
Background Blood polyunsaturated fatty acid (PUFA) levels are determined by diet and by endogenous synthesis via Δ5- and Δ6-desaturases (encoded by the FADS1 and FADS2 genes, respectively). Genome-wide association studies have reported associations between FADS1-FADS2 polymorphisms and the plasma concentrations of PUFAs, HDL- and LDL-cholesterol, and triglycerides. However, much remains unknown regarding the molecular mechanisms explaining how variants affect the function of FADS1-FADS2 genes. O...
Published on Jun 1, 2018in International Journal of Epidemiology7.34
Majid Ezzati103
Estimated H-index: 103
Bin Zhou16
Estimated H-index: 16
+ 842 AuthorsShirin Djalalinia19
Estimated H-index: 19
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood press...
Published on Feb 1, 2018in Journal of Stroke & Cerebrovascular Diseases1.65
Aline Meirhaeghe36
Estimated H-index: 36
(Pasteur Institute),
Dominique Cottel34
Estimated H-index: 34
(Pasteur Institute)
+ 4 AuthorsJean Dallongeville66
Estimated H-index: 66
(Pasteur Institute)
Background Age and sex have a major impact on stroke onset. Aims We aimed to compare the attack, incidence, and 28-day mortality rate for stroke as well as risk factors in men and women aged 35 and over. Methods Data were obtained between 2008 and 2015 from the stroke population-based registry covering the city of Lille (northern France). Results A total of 2426 strokes (1917 incident strokes) were recorded. The number of strokes was lower in women than in men when considering individuals under ...
Published on Dec 1, 2017in The Lancet59.10
Leandra Abarca-Gómez3
Estimated H-index: 3
Ziad Abdeen25
Estimated H-index: 25
+ 1020 AuthorsCarlos A. Aguilar-Salinas49
Estimated H-index: 49
Summary Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants ag...
Published on Jul 1, 2017in Clinical Nutrition6.40
Julie Dumont18
Estimated H-index: 18
(Pasteur Institute),
Louisa Goumidi17
Estimated H-index: 17
(Pasteur Institute)
+ 11 AuthorsJean Ferrièers71
Estimated H-index: 71
(Paul Sabatier University)
Summary Background & aims Blood levels of polyunsaturated fatty acids (PUFAs) are under control of endogenous synthesis via Δ5- and Δ6-desaturases, encoded by the FADS1 and FADS2 genes, respectively and of diet. Genome-wide associations studies (GWAS) reported associations between polymorphisms in FADS1–FADS2 and variations in plasma concentrations of PUFAs, HDL- and LDL-cholesterol and triglycerides. However, it is not established whether dietary PUFAs intake modulates these associations. We as...
Published on Jan 1, 2017in The Lancet59.10
Bin Zhou16
Estimated H-index: 16
(Imperial College London),
James Bentham11
Estimated H-index: 11
(Imperial College London)
+ 756 AuthorsJames Bennett20
Estimated H-index: 20
(Imperial College London)
Summary Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we pooled national, subnational, or community population-based studies that had meas...