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W. Garvey
University of Alabama at Birmingham
EndocrinologyInsulin resistanceInsulinDiabetes mellitusMedicine
221Publications
52H-index
11.8kCitations
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Publications 226
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#1Rogerio Sertie (UAB: University of Alabama at Birmingham)
#2Minsung Kang (UAB: University of Alabama at Birmingham)H-Index: 3
Last. W. Garvey (UAB: University of Alabama at Birmingham)H-Index: 52
view all 7 authors...
Abstract Aims Emerging evidence suggests that during gestation the in utero environment programs metabolism and can increase risk of obesity in adult offspring. Our aim was to study how alterations in maternal diets during gestation might alter body weight evolution, circulating leptin levels and caloric intake in offspring, leading to changes in body composition. Materials and methods We fed gestating rats either a control diet (CD), high fat diet (HFD) or an isocaloric low protein diet (LPD), ...
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#1Jeffrey I. Mechanick (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 39
#2Caroline M. Apovian (BU: Boston University)H-Index: 48
Last. Jennifer Seger (University of Texas Health Science Center at San Antonio)H-Index: 2
view all 21 authors...
OBJECTIVE: The development of these updated clinical practice guidelines (CPGs) was commissioned by the American Association of Clinical Endocrinologists (AACE), The Obesity Society (TOS), American Society for Metabolic and Bariatric Surgery (ASMBS), Obesity Medicine Association (OMA), and American Society of Anesthesiologists (ASA) Boards of Directors in adherence with the AACE 2017 protocol for standardized production of CPGs, algorithms, and checklists. METHODS: Each recommendation was evalua...
1 CitationsSource
#1W. Garvey (UAB: University of Alabama at Birmingham)H-Index: 52
#2Andreas L. Birkenfeld (University of Tübingen)H-Index: 15
Last. Ofri Mosenzon (HUJI: Hebrew University of Jerusalem)H-Index: 21
view all 10 authors...
OBJECTIVE Most individuals with type 2 diabetes also have obesity, and treatment with some diabetes medications, including insulin, can cause further weight gain. No approved chronic weight-management medications have been prospectively investigated in individuals with overweight or obesity and insulin-treated type 2 diabetes. The primary objective of this study was to assess the effect of liraglutide 3.0 mg versus placebo on weight loss in this population. RESEARCH DESIGN AND METHODS Satiety an...
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#1Jeannie Tay (UAB: University of Alabama at Birmingham)H-Index: 7
#2Amy M. Goss (UAB: University of Alabama at Birmingham)H-Index: 8
Last. Barbara A. Gower (UAB: University of Alabama at Birmingham)H-Index: 53
view all 8 authors...
BACKGROUND: Race differences in body composition and fat distribution may in part explain the differences in insulin sensitivity and the disproportionate burden of type 2 diabetes in African Americans. OBJECTIVE: To determine if differences in body composition and fat distribution explain race differences in insulin sensitivity and identify obesity measures that were independently associated with insulin sensitivity. METHODS: Participants were 113 lean, overweight, and obese African-American and...
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#1W. Garvey (UAB: University of Alabama at Birmingham)H-Index: 52
#2Jeffrey I. Mechanick (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 5
OBJECTIVE: Obesity is responsible for a huge burden of suffering and social costs, and yet many patients lack access to evidence-based therapies. The diagnostic term "obesity" and inadequate International Classification of Diseases(ICD) codes contribute to suboptimal efforts to prevent and treat obesity as a chronic disease. The goal of this review is to develop a medically actionable classification system based on the diagnostic term "adiposity-based chronic disease" (ABCD) that reflects diseas...
1 CitationsSource
#1Jeffrey I. Mechanick (Cardiovascular Institute of the South)H-Index: 39
#2Michael E. Farkouh (U of T: University of Toronto)H-Index: 49
Last. W. GarveyH-Index: 52
view all 4 authors...
Highlights •The cardiometabolic-based chronic disease model is designed to optimize early and sustainable preventive care. •Genetics, environment, and behavior are primary drivers, and adiposity and dysglycemia are metabolic drivers of cardiometabolic-based chronic disease. •Cardiometabolic endpoints include coronary heart disease, heart failure, and atrial fibrillation. •A detailed prevention plan can be fashioned based on this model.
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#1Jeffrey I. Mechanick (Cardiovascular Institute of the South)H-Index: 39
#2Michael E. Farkouh (U of T: University of Toronto)H-Index: 49
Last. W. GarveyH-Index: 52
view all 4 authors...
Highlights •The CMBCD prevention care plan is designed to implement early, sustainable, and multimodality protocols for all patients with CVD. •Behavior, adiposity, insulin resistance, dysglycemia, and other MetS traits are the principal targets of the CMBCD preventive care plan for CHD, HF, and AF. •Structured lifestyle change involving healthy eating patterns and physical activity, judicious use of cardioprotective pharmacotherapy based on cardiovascular outcome trial data, and bariatric proce...
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#1Erica M. Schulte (MUSC: Medical University of South Carolina)
#2Peter W. Tuerk (UVA: University of Virginia)H-Index: 19
Last. Patrick M. O'Neil (MUSC: Medical University of South Carolina)H-Index: 34
view all 18 authors...
A WW (formerly Weight Watchers) program adapted for persons with type 2 diabetes mellitus (T2DM) previously was found to be more effective than standard care (SC) intervention for weight loss, improved glycemic control, and weight- and diabetes-related quality of life measures. With data from the same national trial, this study examined whether WW adapted for persons with T2DM also increased engagement in weight control behaviors and decreased hedonic hunger, each of which could contribute to im...
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#1Alan J. GarberH-Index: 41
#2Yehuda HandelsmanH-Index: 41
Last. Jeffrey R. GarberH-Index: 21
view all 19 authors...
Abbreviations: A1C = hemoglobin A1C; AACE = American Association of Clinical Endocrinologists; ABCD = adiposity-based chronic disease; ACCORD = Action to Control Cardiovascular Risk in Diabetes; AC...
3 CitationsSource
#1Dmitry GrapovH-Index: 19
#2Oliver Fiehn (UC Davis: University of California, Davis)H-Index: 80
Last. Sean H. Adams (University of Arkansas for Medical Sciences)H-Index: 34
view all 15 authors...
Insulin resistance has wide-ranging effects on metabolism but there are knowledge gaps regarding the tissue origins of systemic metabolite patterns, and how patterns are altered by fitness and meta...
2 CitationsSource
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