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Daniel J. Conklin
University of Louisville
127Publications
28H-index
2,047Citations
Publications 127
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#2Peter J. Kilfoil (University of Louisville)H-Index: 6
Last.Daniel J. ConklinH-Index: 28
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Abstract Many e-cigarette products contain cinnamaldehyde as a primary constituent of cinnamon flavorings. When used as a food additive, cinnamaldehyde is generally regarded as safe for ingestion. However, little is known about the effects of cinnamaldehyde or its degradation products, generated after heating and inhalation, which may lead to elevated circulatory exposure to the heart. Hence, in this study, we tested the in vitro cardiac toxicity of cinnamaldehyde and its thermal degradation pro...
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#1Lexiao JinH-Index: 1
#2Pawel LorkiewiczH-Index: 14
Last.Daniel J. ConklinH-Index: 28
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Acetaldehyde (AA) is a small, ubiquitous compound present in foods, beverages, as a gas phase combustion product, and also endogenously-generated from metabolism as from ethanol (EtOH). Acetate is a short chain fatty acid derived from AA oxidation, and acetate levels were significantly higher in urine collected overnight with food provided ad libitum compared with urine collected after 9h fasting. Feeding increases gastrointestinal blood flow, and thus, we explored the direct effects of AA (and ...
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#1Pawel Lorkiewicz (AHA: American Heart Association)H-Index: 14
#2Daniel W. Riggs (AHA: American Heart Association)H-Index: 9
Last.Aruni Bhatnagar (AHA: American Heart Association)H-Index: 62
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5 CitationsSource
#1Adjoa BoakyeH-Index: 2
#2Deqing ZhangH-Index: 3
Last.Shahid P. BabaH-Index: 14
view all 15 authors...
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Background Exposure to fine airborne particulate matter (PM 2.5) induces quantitative and qualitative defects in bone marrow–derived endothelial progenitor cells of mice, and similar outcomes in hu...
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#1Rachel J. Keith (University of Louisville)H-Index: 9
#2Daniel W. Riggs (University of Louisville)H-Index: 9
Last.Andrew P. DeFilippis (University of Louisville)H-Index: 21
view all 7 authors...
1 CitationsSource
#1Daniel J. Conklin (University of Louisville)H-Index: 28
#2Suzaynn F. Schick (UCSF: University of California, San Francisco)H-Index: 16
Last.Aruni Bhatnagar (University of Louisville)H-Index: 62
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Although substantial evidence shows that smoking is positively and robustly associated with cardiovascular disease (CVD), the CVD risk associated with the use of new and emerging tobacco products, ...
1 CitationsSource
#1Daniel J. Conklin (University of Louisville)H-Index: 28
#2Yiru Guo (University of Louisville)H-Index: 46
Last.Aruni Bhatnagar (University of Louisville)H-Index: 62
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Although transient receptor potential ankyrin 1 (TRPA1) activation is known to mediate increased blood flow, edema, and pain reception, its role in myocardial ischemia-reperfusion (I/R) injury is u...
5 CitationsSource
#1Lexiao Jin (WMU: Wenzhou Medical College)H-Index: 1
Last.Daniel J. ConklinH-Index: 28
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Formaldehyde (FA), the smallest aldehyde, is generated endogenously, and is widespread in the environment in foods, beverages and as a gas phase product of incomplete combustion. The main metabolite of FA, formate, was increased significantly in murine urine (3x) after overnight feeding. Because feeding increases mesenteric blood flow, we explored the direct effects of FA in isolated murine superior mesenteric artery (SMA). Over the concentration range of 30-1,200 μM, FA strongly and reversibly...
2 CitationsSource
#1Wesley Abplanalp (University of Louisville)H-Index: 5
#2Nalinie S. Wickramasinghe (University of Louisville)H-Index: 10
Last.Timothy E. O'Toole (University of Louisville)H-Index: 20
view all 8 authors...
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