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Marko Kerac
University of London
Intensive care medicinePediatricsSevere Acute MalnutritionMalnutritionMedicine
102Publications
18H-index
1,050Citations
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Publications 103
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#1Severine FrisonH-Index: 5
#2Chloe AngoodH-Index: 2
Last. Philip JamesH-Index: 24
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BACKGROUND: An estimated 49.5 million children under five years of age are wasted. There is a lack of robust studies on effective interventions to prevent wasting. The aim of this study was to identify and prioritise the main outstanding research questions in relation to wasting prevention to inform future research agendas. METHOD: A research prioritisation exercise was conducted following the Child Health and Nutrition Research Initiative method. Identified research gaps were compiled from mult...
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#1Emily DeLacey (Lond: University of London)
#2Cally J TannH-Index: 9
Last. Marko Kerac (Lond: University of London)H-Index: 18
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Background There are an estimated 2.7 million children living within institutionalized care worldwide. This review aimed to evaluate currently available data on the nutrition status of children living within institutionalized care.
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#1Celine BourdonH-Index: 8
#2Natasha Lelijveld (UCL: University College London)H-Index: 4
Last. Moffat J. Nyirenda (Malawi-Liverpool-Wellcome Trust Clinical Research Programme)H-Index: 22
view all 13 authors...
Abstract Background More children are now surviving severe acute malnutrition (SAM), but evidence suggests that early-life malnutrition is associated with increased risk of long-term cardio-metabolic disorders. To better understand potential mechanisms, we studied the metabolite profiles of children seven years after treatment for SAM. Methods We followed-up children (n = 352) treated for SAM in 2006–2007, at Queen Elizabeth Central Hospital, in Malawi. Using nuclear magnetic resonance spectrosc...
1 CitationsSource
#1Victor O. Owino (IAEA: International Atomic Energy Agency)H-Index: 13
#2Alexia A.J. Murphy-Alford (IAEA: International Atomic Energy Agency)
Last. Alan Jackson (Southampton General Hospital)H-Index: 86
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Severe and moderate acute malnutrition are among the leading causes of mortality among children in low‐ and middle‐income countries. There is strong evidence that growth assessed anthropometrically from conception to 2 years of age marks later risk of ill health. This is central to the concept of the developmental origins of adult disease and is presumed to be related to modification of developmental processes during critical “window(s)” of vulnerability. Interventions to treat acute malnutritio...
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#1Natasha LelijveldH-Index: 4
Last. Marko KeracH-Index: 18
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OBJECTIVE: To assess differences in cognition functions and gross brain structure in children seven years after an episode of severe acute malnutrition (SAM), compared with other Malawian children. DESIGN: Prospective longitudinal cohort assessing school grade achieved and results of five computer-based (CANTAB) tests, covering three cognitive domains. A subset underwent brain MRI scans which were reviewed using a standardized checklist of gross abnormalities and compared with a reference popula...
1 CitationsSource
#1Marko Kerac (Lond: University of London)H-Index: 18
#2Severine Frison (Lond: University of London)H-Index: 5
Last. Marie McGrathH-Index: 10
view all 5 authors...
Background Tackling malnutrition is a global health priority, helping children both survive and thrive. Acute malnutrition (wasting) in infants aged under 6 months (u6m) is often neglected. Worldwide, some 8.5 million infants u6m are affected yet recent World Health Organization malnutrition guidelines highlight numerous evidence gaps on how to best manage them. To inform future research, policy and programming, we aimed to identify risk factors associated with infant u6m wasting. Methods We did...
1 CitationsSource
#1Martha MwangomeH-Index: 11
#2Moses NgariH-Index: 9
Last. James A. BerkleyH-Index: 41
view all 7 authors...
The World Health Organization currently defines severe acute malnutrition (SAM) in infants aged under 6 months of age using weight-for-length Z score (WLZ). Given widespread use of mid-upper arm circumference (MUAC) for identifying SAM in older children and weight-for-age (WAZ) for growth monitoring, there is increasing debate about the optimal anthropometric criteria to best identify infants u6m at-risk of mortality. To determine the discriminatory value for mortality during the first 12 months...
1 CitationsSource
#2Wieger P. Voskuijl (UNIMA: University of Malawi)H-Index: 14
Last. James A. BerkleyH-Index: 41
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Background Children with medically complicated severe acute malnutrition (SAM) have high risk of inpatient mortality. Diarrhea, carbohydrate malabsorption, and refeeding syndrome may contribute to early mortality and delayed recovery. We tested the hypothesis that a lactose-free, low-carbohydrate F75 milk would serve to limit these risks, thereby reducing the number of days in the stabilization phase. Methods and findings In a multicenter double-blind trial, hospitalized severely malnourished ch...
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#1Sarah A MorganH-Index: 1
#2Tony WaterstonH-Index: 12
Last. Marko Kerac (Lond: University of London)H-Index: 18
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We welcome the renewed attention that van Tulleken has brought to the important matter of infant formula advertising in medical journals.12 We are especially happy to hear that The BMJ is reviewing its policies on accepting advertising …
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#1Abigail WardH-Index: 4
Last. Arnaud Le MenachH-Index: 18
view all 15 authors...
Integrating seasonal malaria chemoprevention (SMC), recommended by the WHO since 2012 to prevent malaria infection, with nutrition interventions may improve health outcomes and operational efficiencies. This study assessed the effects of co-packaging interventions on distribution coverage, nutrition, and clinical malaria outcomes in northern Nigeria. From August to November 2014, community volunteers delivered sulfadoxine-pyrimethamine and amodiaquine (SP-AQ) door-to-door each month to approxima...
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