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Andrew D. Redd
National Institutes of Health
VirologyImmunologyPopulationMedicineBiology
67Publications
19H-index
1,485Citations
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Publications 70
Newest
#1Jessica L. Prodger (UWO: University of Western Ontario)H-Index: 1
#2Adam A. Capoferri (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 9
Last. Kyungyoon J. Kwon (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 4
view all 16 authors...
HIV-1 remains incurable due to the persistence of proviral DNA integrated into host cells, providing a reservoir for viral rebound upon cessation of antiretroviral therapy (ART). There is evidence for sex-based differences in HIV-1 immune responses and pathogenesis, but little is known about differences in HIV-1 persistence. To address this knowledge gap, we quantified persistent HIV-1 in 90 adults on suppressive ART in Rakai, Uganda (57 females). Total HIV-1 DNA was quantified by PCR and replic...
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#1Susanna L. LamersH-Index: 20
#2Rebecca RoseH-Index: 10
Last. Ronald H Gray (Johns Hopkins University)H-Index: 79
view all 12 authors...
The Rakai Community Cohort Study in south central Uganda has surveyed persons aged 15-49 since 1994. Antiretroviral therapy (ART) was introduced in 2004. HIV p24 and gp41 subtype distribution and viral diversity were studied from blood samples collected at three surveys in 1994-1995, 2002-2003, 2008-2009 which were compared to a new survey round from 2011-2012. These included 1364 HIV+ individuals. For both p24 and gp41 domains, the genetic diversity within subtypes A and D was significantly inc...
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#1Andrew D. Redd (NIH: National Institutes of Health)H-Index: 19
#2Nicole A. Doria-Rose (Vaccine Research Center)H-Index: 35
Last. Thomas C. Quinn (NIH: National Institutes of Health)H-Index: 108
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#1Christine M. Durand (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 25
#2William A. Werbel (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 1
Last. Dorry L. Segev (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 71
view all 34 authors...
We represent a group of investigators funded by the National Institutes of Health (R01AI120938, U01AI134591, U01AI138897) to conduct a prospective multicenter study of the landscape of HIV-infected (HIV+) donors and two prospective multicenter trials comparing outcomes between HIV+ recipients of HIV+ and non-HIV+ donor kidneys and livers. These clinical trials are ongoing (NCT02602262, NCT03500315, NCT03734393).
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#1Oliver Ratmann (Imperial College London)H-Index: 13
#2Joseph KagaayiH-Index: 25
Last. Aaron A. R. TobianH-Index: 40
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Summary Background International and global organisations advocate targeting interventions to areas of high HIV prevalence (ie, hotspots). To better understand the potential benefits of geo-targeted control, we assessed the extent to which HIV hotspots along Lake Victoria sustain transmission in neighbouring populations in south-central Uganda. Methods We did a population-based survey in Rakai, Uganda, using data from the Rakai Community Cohort Study. The study surveyed all individuals aged 15–4...
4 CitationsSource
HIV-Positive–to–HIV-Positive Renal Transplantation Extending the organ donor pool is needed. In this report, investigators from South Africa report the 5-year outcomes of renal transplantation in h...
1 CitationsSource
#1Rebecca RoseH-Index: 10
#2Matthew Hall (University of Oxford)H-Index: 21
Last. Oliver Laeyendecker (Johns Hopkins University)H-Index: 43
view all 27 authors...
BACKGROUND: We evaluated use of phylogenetic methods to predict the direction of HIV transmission. METHODS: For 33 index-partner pairs with genetically-linked infection, samples were collected from partners and indexes close to time of partners' seroconversion (SC); 31 indexes also had an earlier sample. Phylogenies were inferred using env next-generation sequences (one tree per pair/subtype). Direction of transmission (DoT) predicted from each tree was classified as correct or incorrect based o...
1 CitationsSource
#1Adam A. Capoferri (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 9
#2B A Lynch (JHUSOM: Johns Hopkins University School of Medicine)
Last. Andrew D. Redd (NIH: National Institutes of Health)H-Index: 19
view all 10 authors...
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#1Rebecca RoseH-Index: 10
#2Andrew D. Redd (NIH: National Institutes of Health)H-Index: 19
Last. Oliver Laeyendecker (NIH: National Institutes of Health)H-Index: 43
view all 24 authors...
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#1Christine M. Durand (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 25
#2Samantha E. Halpern (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 2
Last. Dorry L. Segev (Johns Hopkins University)H-Index: 71
view all 22 authors...
4 CitationsSource
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