Leila Rooshenas
University of Bristol
Publications 93
#1Samantha Husbands (UoB: University of Bristol)H-Index: 4
#2Fergus Caskey (UoB: University of Bristol)H-Index: 23
Last.Leila Rooshenas (UoB: University of Bristol)H-Index: 7
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Recruitment to randomised controlled trials (RCTs) is challenging. Pre-trial qualitative research provides insights into the feasibility and acceptability of proposed trial designs and delivery; however, this is rarely conducted. This paper reports on work undertaken in advance of the Prepare for Kidney Care trial (formerly PrepareME), which compares preparing for dialysis with preparing for conservative care for patients with chronic kidney disease. The paper describes how the findings refined ...
Primary surgical abdominal wounds are usually covered with a dressing. However, little is known about the practical issues and costs around these dressings. This study aimed to provide an in-depth ...
#1Nicola Harman (University of Liverpool)H-Index: 10
#2Daisy Elliott (UoB: University of Bristol)H-Index: 5
Last.Gillian W. Shorter (Ulster University)H-Index: 13
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#1Natalie S Blencowe (UoB: University of Bristol)H-Index: 15
#2Leila Rooshenas (UoB: University of Bristol)H-Index: 7
Last.Jane M Blazeby (UoB: University of Bristol)H-Index: 58
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Background:Wound healing after surgery may be complicated by surgical site infection (SSI). SSI development may be influenced by surgical techniques surrounding primary wound closure; for example, ...
#1Christel McMullan (University of Birmingham)H-Index: 7
#2Jane M BlazebyH-Index: 58
Last.Rhiannon C MacefieldH-Index: 13
view all 9 authors...
#1Barnaby C ReevesH-Index: 51
#2Leila Rooshenas (UoB: University of Bristol)H-Index: 7
Last.Ananthavarathan P Blazeby Jm (University Hospitals Bristol NHS Foundation Trust)
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#1Timothy JonesH-Index: 9
#2Andrew Carr (NOC: Nuffield Orthopaedic Centre)H-Index: 93
Last.William HollingworthH-Index: 46
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Objectives To illustrate the need for better evaluation of surgical procedures, we investigated the use and cost of subacromial decompression in England over the last decade compared with other countries and explored how this related to the conduct and outcomes of randomised, placebo-controlled clinical trials. Design Longitudinal observational study using Hospital Episode Statistics linked to Payment by Results tariffs in England, 2007/2008 to 2016/2017. Setting Hospital care in England; Finlan...
#1Leila Rooshenas (UoB: University of Bristol)H-Index: 7
#2Sangeetha Paramasivan (UoB: University of Bristol)H-Index: 10
Last.Jenny L DonovanH-Index: 82
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Randomized controlled trials (RCTs) can provide high quality evidence about the comparative effectiveness of health care interventions, but many RCTs struggle with or fail to complete recruitment. ...
2 CitationsSource
#1J SteinRobertH-Index: 60
#2Luke Hughes-DaviesH-Index: 18
Last.Janet A. DunnH-Index: 45
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Background:Multi-parameter tumour gene expression assays (MPAs) are widely used to estimate individual patient residual risk and to guide chemotherapy use in hormone-sensitive, HER2-negative early breast cancer. The TAILORx trial supports MPA use in a node-negative population. Evidence for MPA use in node-positive breast cancer is limited. OPTIMA (Optimal Personalised Treatment of early breast cancer usIng Multi-parameter Analysis) (ISRCTN42400492) aims to validate MPAs as predictors of chemothe...
#1Leila Rooshenas (UoB: University of Bristol)H-Index: 7
#2Lauren J Scott (UoB: University of Bristol)H-Index: 9
Last.Jenny L DonovanH-Index: 82
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Abstract Objective To evaluate the impact of the QuinteT Recruitment Intervention (QRI) on recruitment in challenging randomized controlled trials (RCTs) that have applied the intervention. The QRI aims to understand recruitment difficulties and then implements “QRI actions” to address these as recruitment proceeds. Study Design and Setting A mixed-methods study, comprising (1) before-and-after comparisons of recruitment rates and the numbers of patients approached and (2) qualitative case studi...
5 CitationsSource