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Cornelius Weiller
University of Freiburg
PsychologyNeuroscienceAnesthesiaStrokeMedicine
480Publications
80H-index
21.6kCitations
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Publications 449
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#1Lena-Alexandra Beume (University Medical Center Freiburg)
#2Michel Rijntjes (University Medical Center Freiburg)H-Index: 33
Last. R. UmarovaH-Index: 12
view all 11 authors...
Abstract Visual neglect and extinction are two distinct visuospatial attention deficits that frequently occur after right hemisphere cerebral stroke. However, their different lesion profiles remain a matter of debate. In the left hemisphere, a domain-general dual-loop model with distinct computational abilities onto which several cognitive functions may project, has been proposed: a dorsal stream for sensori-motor mapping in time and space and a ventral stream for comprehension and representatio...
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#1Hannah FuhrerH-Index: 4
Last. Stephan MeckelH-Index: 6
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Background and purpose Mechanical thrombectomy (MT) improves early clinical outcome in patients with acute ischemic stroke but insights on determinants of long-term outcome after MT treatment are scarce.
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#1Andrea DreßingH-Index: 1
Last. Michel RijntjesH-Index: 33
view all 8 authors...
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#1Tobias Bormann (University of Freiburg)H-Index: 9
#2Margret SeybothH-Index: 2
Last. Cornelius Weiller (University of Freiburg)H-Index: 80
view all 4 authors...
Abstract Verbal short-term memory (vSTM) plays a crucial role in word learning, and patients with impaired vSTM have been demonstrated to fail on learning novel word forms. Word learning has exclusively been investigated with previously unknown or pseudowords. Several languages, however, make use of composition, i.e., combining morphemes into compounds. On the one hand, this is comparable to pseudoword learning because known elements are combined into novel representations, on the other hand com...
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BACKGROUND AND OBJECTIVES: To evaluate tau PET using C-pyridinyl-butadienyl-benzothiazole 3 (C-PBB3) in the 4-repeat (4R)-tauopathies progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). METHODS: Retrospective analysis of C-PBB3 PET in 2, 7, and 2 patients with CBS, PSP, and Alzheimer dementia (AD), respectively. Normalized C-PBB3 uptake in clusters with significant hypometabolism on F-FDG-PET and corresponding atlas-based volumes of interest was compared between diagnostic grou...
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#1Anika Stockert (Leipzig University)H-Index: 4
#2Max Wawrzyniak (Leipzig University)H-Index: 3
Last. Dorothee Saur (Leipzig University)H-Index: 24
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The loss and recovery of language functions are still incompletely understood. This longitudinal functional MRI study investigated the neural mechanisms underlying language recovery in patients with post-stroke aphasia putting particular emphasis on the impact of lesion site. To identify patterns of language-related activation, an auditory functional MRI sentence comprehension paradigm was administered to patients with circumscribed lesions of either left frontal (n = 17) or temporo-parietal (n ...
3 CitationsSource
#1Farsin HamzeiH-Index: 22
#2Gabriele Erath (University of Freiburg)
Last. Michel Rijntjes (University of Freiburg)H-Index: 33
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To improve clinical outcome, one longstanding goal in treating stroke patients has been an individual therapy based on functional and anatomical knowledge of the single patient. Therefore, in this study brain imaging of 36 chronic stroke patients was analyzed to identify parameters predicting clinical recovery. T1-weighted MRI was acquired to assess the lesion; functional MRI was used to visualize existing resources; DTI for the integrity of the corticospinal tract (CST) and long association tra...
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#1Jonas A. Hosp (University of Freiburg)H-Index: 2
#1Jonas A. Hosp (University Medical Center Freiburg)
Last. Marco Reisert (University Medical Center Freiburg)H-Index: 23
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In humans, sensorimotor cortical areas receive relevant dopaminergic innervation—although an anatomic description of the underlying fiber projections is lacking so far. In general, dopaminergic projections towards the cortex originate within the ventral tegmental area (VTA) and are organized in a meso-cortico-limbic system. Using a DTI-based global tractography approach, we recently characterized the superolateral branch of the medial forebrain bundle (slMFB), a prominent pathway providing dopam...
1 CitationsSource
#1Andrea Dressing (University of Freiburg)H-Index: 5
#2Christoph P. Kaller (University of Freiburg)H-Index: 21
Last. Markus Martin (University of Freiburg)H-Index: 7
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Abstract Behavioral deficits after stroke like apraxia can be related to structural lesions and to a functional state of the underlying network – three factors, reciprocally influencing each other. Combining lesion data, behavioral performance and passive functional activation of the network-of-interest, this study aims to disentangle those mutual influences and to identify 1) activation patterns associated with the presence or absence of acute apraxia in tool-associated actions and 2) the speci...
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#1Sandra V. LoosliH-Index: 4
#2Tobias Bormann (University of Freiburg)H-Index: 9
Last. Christoph P. KallerH-Index: 21
view all 8 authors...
Abstract Inhibition is not a unitary construct, as different inhibition-related functions have been disentangled. The present single-case study compares performance of a patient with bilateral lesions in the inferior frontal gyrus (IFG) and anterior insula to healthy age-matched controls in different inhibition-related tasks. Particular focus was on the resolution of proactive interference that is supposed to rely on bilateral IFG and anterior insula. Two working memory tasks previously proven s...
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