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Justine Fam
University of New South Wales
10Publications
3H-index
36Citations
Publications 10
Newest
Published on Jul 2, 2019
Justine Fam3
Estimated H-index: 3
(UNSW: University of New South Wales),
Jessica C. Lee4
Estimated H-index: 4
(UNSW: University of New South Wales)
The number of students enrolling in postgraduate by research degrees has seen a large increase in recent years, a trend which is evident globally as well as within Australia. However, the rate at which PhD students are dropping out has also increased, indicating that students are not receiving adequate resources to support them throughout their candidature. We highlight that mentoring programs are effective in addressing inequality between PhD students, and describe a program that we have recent...
Published on Dec 1, 2018in Scientific Reports4.01
A. J. Delaney2
Estimated H-index: 2
(CSU: Charles Sturt University),
James W. Crane13
Estimated H-index: 13
(UTAS: University of Tasmania)
+ 2 AuthorsR. F. Westbrook2
Estimated H-index: 2
(UNSW: University of New South Wales)
The two main sub-divisions of the Central amygdala (CeA), the lateral-capsular (CeA-LC) and the medial (CeA-M), contain extensive networks of inhibitory interneurons. We have previously shown that activation of GABAB-receptors reduces excitatory transmission between axons of the pontine parabrachial nucleus and neurons of the CeA-LC by inhibiting glutamate release from presynaptic terminals13. Here we have characterised GABAB-receptor activation on other excitatory and inhibitory projections wit...
Published on Oct 1, 2018in Psychoneuroendocrinology4.01
Justine Fam3
Estimated H-index: 3
(UNSW: University of New South Wales),
Nathan M. Holmes8
Estimated H-index: 8
(UNSW: University of New South Wales)
+ 2 AuthorsR. Frederick Westbrook28
Estimated H-index: 28
(UNSW: University of New South Wales)
Oxytocin (OT) is a neuropeptide which influences the expression of social behavior and regulates its distribution according to the social context - OT is associated with increased pro-social effects in the absence of social threat and defensive aggression when threats are present. The present experiments investigated the effects of OT beyond that of social behavior by using a discriminative Pavlovian fear conditioning protocol with rats. In Experiment 1, an OT receptor agonist (TGOT) microinject...
Published on Dec 1, 2017in Scientific Reports4.01
Nathan M. Holmes8
Estimated H-index: 8
(UNSW: University of New South Wales),
James W. Crane13
Estimated H-index: 13
(CSU: Charles Sturt University)
+ 3 AuthorsA. J. Delaney2
Estimated H-index: 2
(CSU: Charles Sturt University)
The central amygdala is critical for the acquisition and expression of fear memories. This region receives a dense innervation from brainstem noradrenergic cell groups and has a high level of α2-adrenoceptor expression. Using whole-cell electrophysiological recordings from rat brain slices, we characterise the role of pre-synaptic α2-adrenoceptor in modulating discrete inhibitory and excitatory connections within both the lateral and medial division of the central amygdala. The selective α2-adre...
Published on Jan 1, 2017in Addiction Biology4.22
Carmen Huynh1
Estimated H-index: 1
(UNSW: University of New South Wales),
Justine Fam3
Estimated H-index: 3
(UNSW: University of New South Wales)
+ 1 AuthorsKelly J. Clemens17
Estimated H-index: 17
(UNSW: University of New South Wales)
Drug use may be exacerbated in environments which lack alternative means of engaging in rewarding behaviour. When alternative rewards are available, drug use may decrease-an effect that can be harnessed for therapeutic benefit. This idea is particularly well-supported by recent preclinical evidence demonstrating that a majority of rats will readily choose a potent non-drug reward over cocaine or heroin. Here we examine whether the same holds true for nicotine, a drug considered to have one of th...
Published on Aug 1, 2016in Scientific Reports4.01
Justine Fam3
Estimated H-index: 3
,
Fred Westbrook4
Estimated H-index: 4
,
Ehsan Arabzadeh22
Estimated H-index: 22
Identifying similarities and differences in choice behavior across species is informative about how basic mechanisms give rise to more complex processes. In the present study, we compared pre- and post-choice latencies between rats and humans under two paradigms. In Experiment 1, we used a cued choice paradigm where subjects were presented with a cue that directed them as to which of two options to respond for rewards. In Experiment 2, subjects were free to choose between two options in order to...
Nathan M. Holmes8
Estimated H-index: 8
(UNSW: University of New South Wales),
Kate Hutton-Bedbrook1
Estimated H-index: 1
(UNSW: University of New South Wales)
+ 1 AuthorsR. Frederick Westbrook28
Estimated H-index: 28
(UNSW: University of New South Wales)
Published on Sep 29, 2015in Frontiers in Behavioral Neuroscience2.62
Justine Fam3
Estimated H-index: 3
(UNSW: University of New South Wales),
Fred Westbrook4
Estimated H-index: 4
(UNSW: University of New South Wales),
Ehsan Arabzadeh22
Estimated H-index: 22
(ANU: Australian National University)
One characteristic of natural environments is that outcomes vary across time. Animals need to adapt to these environmental changes and adjust their choices accordingly. In this experiment, we investigated the sensitivity with which rats could detect, and adapt to, multiple changes in the environment. Rats chose between two spouts which delivered 5% sucrose rewards with distinct probabilities. Across three phases, reward probabilities changed in size (large or small) and direction (increase or de...
Published on Mar 22, 2015
Justine Fam3
Estimated H-index: 3
(UNSW: University of New South Wales),
Fred Westbrook4
Estimated H-index: 4
(UNSW: University of New South Wales),
Ehsan Arabzadeh22
Estimated H-index: 22
(ANU: Australian National University)
We simulate two types of environments to investigate how closely rats approximate optimal foraging. Rats initiated a trial where they chose between two spouts for sucrose, which was delivered at distinct probabilities. The discrete trial procedure used allowed us to observe the relationship between choice proportions, response latencies and obtained rewards. Our results show that rats approximate the optimal strategy across a range of environments that differ in the average probability of reward...
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