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Harry R. Büller
University of Amsterdam
SurgeryPulmonary embolismThrombosisDiabetes mellitusMedicine
630Publications
92H-index
37.4kCitations
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Publications 635
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#1Yassene Mohammed (UVic: University of Victoria)H-Index: 10
#2Ruud S. Kootte (UvA: University of Amsterdam)H-Index: 13
Last. Thijs E. van Mens (UvA: University of Amsterdam)H-Index: 3
view all 8 authors...
Background: The intestinal microbiome plays a versatile role in the etiology of arterial thrombosis. In venous thrombosis, driven chiefly by plasma coagulation, no such role has yet been established. We hypothesized that the intestinal microbiome composition affects coagulation in humans. Methods: We used healthy donor fecal microbiota transplant (FMT) to experimentally change the microbiome composition in metabolic syndrome patients. Thirty-five subjects were randomized in a blinded fashion to ...
1 CitationsSource
#1Tobias Tritschler (Ottawa Hospital Research Institute)H-Index: 4
#2Noémie Kraaijpoel (UvA: University of Amsterdam)H-Index: 6
Last. Grégoire Le Gal (Ottawa Hospital Research Institute)H-Index: 10
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INTRODUCTION Pulmonary embolism (PE)-related death is often part of the primary outcome in venous thromboembolism (VTE) studies. The Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis developed a definition for PE-related death and classification of the cause of death. The present survey evaluated a preliminary version of this definition and classification. METHODS Sixty-nine VTE experts from 9 countries were invited for a cross-sectional on...
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#1Noémie Kraaijpoel (UvA: University of Amsterdam)H-Index: 6
#2Marc Carrier (Ottawa Hospital Research Institute)H-Index: 41
Last. P. M. M. Bossuyt (UvA: University of Amsterdam)H-Index: 110
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Background Compression ultrasonography (CUS) is the first-line imaging test in the diagnostic management of suspected deep vein thrombosis (DVT) of the lower extremity. Three CUS strategies are used in clinical practice. However, their relative diagnostic accuracy is uncertain. Objectives This systematic review and meta-analysis aimed to summarize and compare the diagnostic accuracy of single limited, serial limited, and whole-leg CUS for DVT. Methods MEDLINE, Embase, and CENTRAL were searched f...
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#1Frits I. Mulder (UvA: University of Amsterdam)H-Index: 2
#2Marcello Di NisioH-Index: 30
Last. Nick van Es (UvA: University of Amsterdam)H-Index: 17
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Introduction In cancer patients, current guidance suggests similar treatment for incidental and symptomatic venous thromboembolism (VTE), mainly based on retrospective data. We aimed to evaluate anticoagulant therapy in cancer patients with incidental and symptomatic VTE. Methods The Hokusai VTE Cancer study was a randomised controlled trial comparing edoxaban with dalteparin for cancer-associated VTE. The primary outcome was the composite of first recurrent VTE or major bleeding. Secondary outc...
1 CitationsSource
#1Frits I. Mulder (UvA: University of Amsterdam)H-Index: 2
#2Noémie Kraaijpoel (UvA: University of Amsterdam)H-Index: 6
Last. Nick van Es (UvA: University of Amsterdam)H-Index: 17
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Abstract Background The Ottawa score was previously developed to predict recurrent venous thromboembolism (VTE) in cancer patients with VTE. The performance of this score in patients with incidental VTE is currently unclear. Aim To evaluate the performance of the Ottawa risk score in cancer patients with incidental pulmonary embolism included in an international, prospective, observational cohort study. Methods The score was used to classify patients as high (≥1), intermediate (0), or low risk (...
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#1Marcello Di NisioH-Index: 30
#2Nick van EsH-Index: 17
Last. Gary E. Raskob (University of Oklahoma Health Sciences Center)H-Index: 73
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Background: Patients with active cancer and venous thromboembolism (VTE) are at high risk of recurrence. Therefore, continued anticoagulant therapy beyond the initial 6 months is suggested in this patient population, but evidence supporting this approach is limited. Methods: The Hokusai VTE Cancer trial compared edoxaban with dalteparin for VTE treatment in patients with active cancer. This post hoc analysis focused on the follow-up period from 6 to 12 months. The primary outcome was the composi...
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#1Faizan Khan (Ottawa Hospital Research Institute)H-Index: 8
#2Alvi Rahman (McGill University)H-Index: 1
Last. Marc A. Rodger (Ottawa Hospital Research Institute)H-Index: 48
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Abstract Objectives To determine the rate of a first recurrent venous thromboembolism (VTE) event after discontinuation of anticoagulant treatment in patients with a first episode of unprovoked VTE, and the cumulative incidence for recurrent VTE up to 10 years. Design Systematic review and meta-analysis. Data sources Medline, Embase, and the Cochrane Central Register of Controlled Trials (from inception to 15 March 2019). Study selection Randomised controlled trials and prospective cohort studie...
4 CitationsSource
#1Noémie Kraaijpoel (UvA: University of Amsterdam)H-Index: 6
#2S.M. Bleker (UvA: University of Amsterdam)H-Index: 4
Last. Marcello Di NisioH-Index: 30
view all 21 authors...
PURPOSEPulmonary embolism is incidentally diagnosed in up to 5% of patients with cancer on routine imaging scans. The clinical relevance and optimal therapy for incidental pulmonary embolism, parti...
3 CitationsSource
#1Maha A. T. Elsebaie (Ain Shams University)H-Index: 2
#2Nick van EsH-Index: 17
Last. Manila Gaddh (Emory University)H-Index: 7
view all 5 authors...
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#1Elise SchapkaitzH-Index: 4
#2B.F. JacobsonH-Index: 11
Last. Harry R. BüllerH-Index: 92
view all 4 authors...
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