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John A. Joska
University of Cape Town
150Publications
24H-index
2,176Citations
Publications 154
Newest
#1Monray E. Williams (UCT: University of Cape Town)
#2Simo S. Zulu (UCT: University of Cape Town)
Last.Petrus J. W. Naudé (UCT: University of Cape Town)H-Index: 2
view all 5 authors...
Abstract HIV-associated neurocognitive impairments (HANI) are a spectrum of neurological disorders due to the effects of HIV-1 on the central nervous system (CNS). The HIV-1 subtypes; HIV-1 subtype B (HIV-1B) and HIV-1 subtype C (HIV-1C) are responsible for the highest prevalence of HANI and HIV infections respectively. The HIV transactivator of transcription (Tat) protein is a major contributor to the neuropathogenesis of HIV. The effects of the Tat protein on cells of the CNS is determined by ...
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#1Lena S. AndersenH-Index: 2
#2John A. JoskaH-Index: 24
Last.Steven A. SafrenH-Index: 42
view all 8 authors...
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#1Brandon A. KnettelH-Index: 3
#2Corne RobertsonH-Index: 3
Last.Kathleen J. SikkemaH-Index: 45
view all 7 authors...
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#1Monray E. Williams (UCT: University of Cape Town)
#2Jonathan C Ipser (UCT: University of Cape Town)H-Index: 25
Last.Petrus J. W. Naudé (UCT: University of Cape Town)H-Index: 2
view all 5 authors...
Dysregulated expression of neuro-immune markers has previously been linked to HIV-associated neurocognitive impairment. We undertook an exploratory approach in a HIV clade-C cohort, investigating the association between eight immune markers and neurocognitive performance in 99 HIV+ and 51 HIV- participants. Markers were selected on preliminary and putative evidence of their link to key neuro-immune functions. Cognitive performance was established using a battery of tests sensitive to HIV-associa...
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#1Brandon A. Knettel (Duke University)H-Index: 3
#2Marta Mulawa (Duke University)H-Index: 9
Last.Kathleen J. Sikkema (UCT: University of Cape Town)H-Index: 45
view all 7 authors...
ABSTRACTHIV-infected women who have experienced sexual violence face unique challenges in their HIV care engagement and adherence to antiretroviral medications (ARVs). Improving AIDS Care after Tra...
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#1Jessica F. Magidson (UMD: University of Maryland, College Park)H-Index: 16
#2Lena S. Andersen (UCT: University of Cape Town)H-Index: 2
Last.John A. Joska (UCT: University of Cape Town)H-Index: 24
view all 7 authors...
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#1Crick Lund (UCT: University of Cape Town)H-Index: 39
#2Marguerite Schneider (UCT: University of Cape Town)H-Index: 14
Last.Ezra Susser (Columbia University)H-Index: 64
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Abstract The study's objective was to determine the effectiveness of a task-sharing psychological treatment for perinatal depression using non-specialist community health workers. A double-blind individual randomised controlled trial was conducted in two antenatal clinics in the peri-urban settlement of Khayelitsha, Cape Town. Adult pregnant women who scored 13 or above on the Edinburgh Postnatal Depression rating Scale (EPDS) were randomised into the intervention arm (structured six-session psy...
1 CitationsSource
#1John A. JoskaH-Index: 24
#2Anna DreyerH-Index: 1
Last.Celeste A. de JagerH-Index: 20
view all 5 authors...
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#1Talia M. Nir (SC: University of Southern California)H-Index: 17
#2Jean-Paul Fouche (UCT: University of Cape Town)H-Index: 18
Last.Neda Jahanshad (SC: University of Southern California)H-Index: 42
view all 39 authors...
Background: Human immunodeficiency virus type-1 (HIV) infection can be controlled with combination antiretroviral therapy (cART), but neurocognitive impairment remains common even in treated and chronic HIV-infected (HIV+) cohorts. Identifying the neuroanatomical pathways associated with infection has the potential to delineate novel neuropathological processes underlying persisting deficits, yet individual neuroimaging studies have yielded inconsistent findings. The ENIGMA-HIV Working Group was...
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#1Jessica F. Magidson (UMD: University of Maryland, College Park)H-Index: 16
#2John A. Joska (UCT: University of Cape Town)H-Index: 24
Last.Bronwyn Myers (South African Medical Research Council)H-Index: 27
view all 9 authors...
Abstract South Africa is home to the largest number of people living with HIV/AIDS in the world. Alongside the HIV/AIDS epidemic, problematic alcohol and other drug (AOD) use is prevalent and associated with poor HIV treatment and secondary HIV prevention outcomes. International guidelines and local policy both support the integration of mental health care and AOD treatment into HIV care, yet barriers exist to implementation. This study aimed to explore patient and provider perspectives on the i...
1 CitationsSource
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