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Mika Kivimaeki
1,535Publications
117H-index
65.8kCitations
Publications 1535
Newest
Published on Dec 1, 2019in Scientific Reports 4.01
Mohamed Amine Benadjaoud2
Estimated H-index: 2
(Institut de radioprotection et de sûreté nucléaire),
Mehdi Menai8
Estimated H-index: 8
(University of Paris)
+ 5 AuthorsSéverine Sabia35
Estimated H-index: 35
(UCL: University College London)
The association between physical activity and lung function is thought to depend on smoking history but most previous research uses self-reported measures of physical activity. This cross-sectional study investigates whether the association between accelerometer-derived physical activity and lung function in older adults differs by smoking history. The sample comprised 3063 participants (age = 60–83 years) who wore an accelerometer during 9 days and undertook respiratory function tests. Forced v...
Published on Feb 15, 2019in Nature Communications 11.88
Eloïse Berger1
Estimated H-index: 1
(University of Toulouse),
Raphaële Castagné14
Estimated H-index: 14
(University of Toulouse)
+ 17 AuthorsV. Krogh77
Estimated H-index: 77
Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is key in elucidating biological mechanisms underlying socioeconomic disparities. Here we explore the relationship between socioeconomic position (SEP) across the life course and inflammation (as measured by CRP levels) in up to 23,008 participants from six European cohort studies from thr...
Published on Dec 1, 2019in Scientific Reports 4.01
Ana Isabel Ribeiro10
Estimated H-index: 10
(University of Porto),
Sílvia Fraga12
Estimated H-index: 12
(University of Porto)
+ 8 AuthorsPaolo Vineis110
Estimated H-index: 110
(Imperial College London)
Living in deprived neighbourhoods may have biological consequences, but few studies have assessed this empirically. We examined the association between neighbourhood deprivation and allostatic load, a biological marker of wear and tear, taking into account individual's socioeconomic position. We analysed data from three cohort studies (CoLaus-Switzerland; EPIPorto-Portugal; Whitehall II-UK) comprising 16,364 participants. We defined allostatic load using ten biomarkers of dysregulated metabolic,...
Published on Jan 28, 2019in Scientific Reports 4.01
Richard Layte33
Estimated H-index: 33
(Trinity College, Dublin),
Cathal McCrory14
Estimated H-index: 14
(Trinity College, Dublin)
+ 5 AuthorsPaolo Vineis110
Estimated H-index: 110
(Imperial College London)
The status anxiety hypothesis proposes that systematic inflammation as a consequence of chronic psycho-social stress is a possible pathway linking socio-economic position (SEP) to premature ageing and is a possible explanation for cross-national variation in patterns of health and well-being. Harmonised data from the LIFEPATH consortium on 18,349 individuals aged 50 to 75 and 30,632 observations are used to measure variation in the association between inflammation measured as C-reactive protein ...
Published on Mar 14, 2019in Scientific Reports 4.01
Michael P. Gardner15
Estimated H-index: 15
(University of Oxford),
Stafford L. Lightman84
Estimated H-index: 84
+ 10 AuthorsMeena Kumari77
Estimated H-index: 77
(UCL: University College London)
Evidence on the association between functioning of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages is mixed. We undertook a systematic review (until October 2016) and individual participant data (IPD) meta-analysis to test if dysregulation of the HPA axis is associated with worse cognitive capability. Five cohort studies were included in the IPD meta-analysis of diurnal cortisol patterns with crystallised and fluid cognitive ability. Higher night time cortiso...
G. David Batty67
Estimated H-index: 67
(UCL: University College London),
Mika Kivimaeki117
Estimated H-index: 117
(UCL: University College London),
Steven Bell12
Estimated H-index: 12
(University of Cambridge)
Owing to the often prohibitively high costs of medical examinations, or an absence of infrastructure for linkage of study members to morbidity registries, much aetiological research in the field of cardiovascular research relies on death records. Because they are regarded as being more distal to risk factor assessment than morbidity endpoints, mortality data are generally maligned in this context for seemingly providing less clear insights into aetiology. The relative utility of mortality versus...
G. David Batty67
Estimated H-index: 67
(UCL: University College London),
Catharine R. Gale56
Estimated H-index: 56
+ -3 AuthorsSteven Bell12
Estimated H-index: 12
(University of Cambridge)
Background: The UK Biobank cohort study has become a much-utilised and influential scientific resource. With a primary goal of understanding disease aetiology, the low response to the original survey of 5.5% has, however, led to debate as to the generalisability of these findings. We therefore compared risk factor-disease estimations in UK Biobank with those from 18 nationally representative studies with conventional response rates. Methods: We used individual-level baseline data from UK Biobank...
Published in BMJ 27.60
Séverine Sabia35
Estimated H-index: 35
(UCL: University College London),
Aurore Fayosse1
Estimated H-index: 1
(University of Paris)
+ -3 AuthorsArchana Singh-Manoux69
Estimated H-index: 69
(UCL: University College London)
Abstract Objectives To examine the association between the Life Simple 7 cardiovascular health score at age 50 and incidence of dementia. Design Prospective cohort study. Setting Civil service departments in London (Whitehall II study; study inception 1985-88). Participants 7899 participants with data on the cardiovascular health score at age 50. Exposures The cardiovascular health score included four behavioural (smoking, diet, physical activity, body mass index) and three biological (fasting g...
Published in Hypertension 7.02
Masaki Okamoto (UCL: University College London), Martin J. Shipley99
Estimated H-index: 99
(UCL: University College London)
+ -3 AuthorsEric J. Brunner87
Estimated H-index: 87
(UCL: University College London)
Published in Hypertension 7.02
Masaki Okamoto5
Estimated H-index: 5
,
Martin J. Shipley99
Estimated H-index: 99
+ -3 AuthorsEric J. Brunner87
Estimated H-index: 87
Whether poorer pulmonary function accelerates progression of arterial stiffness remains unknown as prior observational studies have not examined longitudinal changes in arterial stiffness in relati...
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