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Peter Pressman
Cedars-Sinai Medical Center
Food additiveChemistryFood scienceMedicineEnvironmental health
24Publications
3H-index
17Citations
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Publications 26
Newest
#1A. Wallace Hayes (USF: University of South Florida)H-Index: 25
#2Peter PressmanH-Index: 3
Last. Klaus WeberH-Index: 102
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Abstract We independently and retrospectively reviewed three studies that evaluated the toxicity of BIA 10–2474 (3-(1-(cyclohexyl(methyl)carbamoyl)-lH-imidazol-4-yl)pyridine 1-oxide), a novel fatty acid amide hydrolase (FAAH) inhibitor in male and female CD-1 mice based upon raw data obtained from Bial Portela & Companhia S.A. (Sao Mamede do Coronado, Portugal). These studies were carried out prior to the clinical trial with BIA 10–2474 and formed part of the regulatory submission. An initial or...
4 CitationsSource
#1A. Wallace Hayes (USF: University of South Florida)H-Index: 25
#2Peter PressmanH-Index: 3
Last. Patrício Soares-da-Silva (Bial)H-Index: 49
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Abstract The present paper describes the regulatory safety pharmacology studies that were carried out to support the clinical trial application for BIA 10–2474. Animal studies complied with worldwide regulatory guidelines (e.g. EEC Council Directive 75/318/EEC and subsequent amendments). Oral administration of BIA 10–2474 at doses of 30, 100 and 300 mg/kg to male Han Wistar rats did not cause any significant physiological or behavioral changes, affect the respiration rate or the tidal volume, th...
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#1Tilakavati Karupaiah (Taylors University)H-Index: 9
#2Khun-Aik Chuah (UKM: National University of Malaysia)H-Index: 1
Last. Kalyana SundramH-Index: 22
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We conducted this cross-sectional population study with a healthy multi-ethnic urban population (n = 577) in Malaysia, combining nutritional assessments with cardiometabolic biomarkers defined by lipid, atherogenic lipoproteins, inflammation and insulin resistance. We found diametrically opposing associations of carbohydrate (246·6 ± 57·7 g, 54·3 ± 6·5%-TEI) and fat (total = 64·5 ± 19·8 g, 31·6 ± 5·5%-TEI; saturated fat = 14·1 ± 2·7%-TEI) intakes as regards waist circumference, HDL-C, blood pres...
1 CitationsSource
#1Peter PressmanH-Index: 3
#2Roger Clemens (SC: University of Southern California)H-Index: 15
Last. A. Wallace Hayes (USF: University of South Florida)H-Index: 7
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Aloe vera plant extracts are ubiquitous in foods, cosmetics, and medicine. Like all plants, these extracts contain an array of potential bioactives or glycans, which may contribute to health when a...
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#1Peter PressmanH-Index: 3
#2A Wallacehayes (Harvard University)H-Index: 24
Last. Roger Clemens (SC: University of Southern California)H-Index: 15
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Federal Government management of health risks associated with the use of therapeutics and unintended environmental chemical exposures must be expedited to meet public health needs. Although US agen...
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#1Anne ConstableH-Index: 18
Last. A. Wallace Hayes (MSU: Michigan State University)H-Index: 7
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During the development of international standards by the Codex Alimentarius Commission, infant foods and their constituent ingredients are subject to rigorous risk analysis and are strictly regulat...
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