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Hiroshi Miyashita
Jichi Medical University
81Publications
19H-index
981Citations
Publications 81
Newest
#1Kazuo Eguchi (Jichi Medical University)H-Index: 37
#2Hiroshi Miyashita (Jichi Medical University)H-Index: 19
Last.Kazuyuki ShimadaH-Index: 64
view all 20 authors...
It is not established whether central blood pressure (BP) evaluated by a radial pulse wave analysis is useful to predict cardiovascular prognoses. We tested the hypothesis that central BP predicts future cardiovascular events in treated hypertensive subjects. We conducted a multicenter, observational cohort study of 3566 hypertensives being treated with antihypertensive medications at 27 institutions in Japan. We performed the radial pulse wave analyses using applanation tonometry in all subject...
3 CitationsSource
#1Mitsuyo Mieda (Jichi Medical University)H-Index: 1
#2Hiroshi Miyashita (Jichi Medical University)H-Index: 19
Last.HironoriYamamoto (Jichi Medical University)H-Index: 53
view all 10 authors...
Abstract Transnasal endoscopy is widely used in screening for upper gastrointestinal lesions because of less associated pain. Nasal bleeding is the most severe adverse effect, but specific risk factors have not been identified. The aim of this study is to identify risk factors for nasal bleeding during transnasal endoscopy. Nasal bleeding occurred in 160/3035 (5.3%) of patients undergoing transnasal endoscopy as part of health checkups. Patient data were retrospectively evaluated including anthr...
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#1Tsuneo Takenaka (International University of Health and Welfare)H-Index: 28
#2Hiromichi Suzuki (Saitama Medical University)H-Index: 29
Last.Kazuyuki ShimadaH-Index: 64
view all 5 authors...
The progression of chronic kidney disease (CKD) inverts the arterial stiffness gradient. However, central hemodynamic pressure profiles in CKD have not been fully examined. A cross-sectional study was performed to assess the relationship between the CKD stage and central hemodynamic processes. The study enrolled 2020 hypertensive patients who had undergone echocardiography and measurement of their serum creatinine levels. Radial tonometry was applied to all patients to measure central blood pres...
2 CitationsSource
#1Kazuo EguchiH-Index: 37
#2Hiroshi Miyashita (Jichi Medical University)H-Index: 19
view all 4 authors...
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#1Supichaya Boonvisut (Jichi Medical University)H-Index: 4
#2Ken Yoshida (Jichi Medical University)H-Index: 1
Last.Sadahiko Iwamoto (Jichi Medical University)H-Index: 13
view all 6 authors...
Background Non-alcoholic fatty liver disease (NAFLD) is a disorder characterized by excessive fat deposits in hepatocytes without excessive alcohol intake. NAFLD is influenced by genetic factors, and the heritability has been estimated at 0.35 to 0.6 by twin studies. We explored rare variants in known NAFLD-associated genes to investigate whether these rare variants are involved in the susceptibility to NAFLD.
3 CitationsSource
#1Kazuhiro Nakayama (Jichi Medical University)H-Index: 13
#2Shinichi Saito (Hokkaido University)H-Index: 1
Last.Hidehisa Shimizu (Hokkaido University)H-Index: 4
view all 11 authors...
The function of aryl hydrocarbon receptor repressor (AHRR) in the kidney is unclear. The present study investigated associations between AHRR Pro189Ala polymorphism and estimated glomerular filtration rates (eGFR), serum creatinine, and hemoglobin levels in 2775 Japanese adults without diabetes. In addition, we examined whether AHRR expression levels in the kidney of control and chronic kidney disease (CKD) rats were changed. Multiple linear regression analyses showed that carriers of the Ala al...
1 CitationsSource
#1Hiroshi Miyashita (Jichi Medical University)H-Index: 19
The time is ripe to reevaluate the second derivative of the digital photoplethysmogram (SDPTG), originating in Japan, as an important tool for cardiovascular risk and central hemodynamic assessment
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#1Shuji TakahashiH-Index: 2
Last.Hiroshi MiyashitaH-Index: 19
view all 6 authors...
A noninvasive estimation of central blood-pressure is required by the researchers or the medical practitioners in the cardiovascular treatment. In this study, first of all, a cardiovascular simulator based on the electrical circuits is described based on the model based approach and then, the representation of aorta model as a pressure transfer function is shown. This representation accelerates the simulator and then, makes it possible to estimate the central blood-pressure from a wearable gouge...
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#1Supichaya Boonvisut (Jichi Medical University)H-Index: 4
#2Kazuhiro Nakayama (Jichi Medical University)H-Index: 13
Last.Sadahiko Iwamoto (Jichi Medical University)H-Index: 13
view all 8 authors...
Background The Neurocan-cartilage intermediate layer protein 2 (NCAN-CILP2) region forms a tight linkage disequilibrium (LD) block and is associated with plasma lipid levels and non-alcoholic fatty liver disease (NAFLD) in individuals of European descent but not in the Malay and Japanese ethnic groups. Recent genome-wide resequence studies identified a missense single-nucleotide polymorphism (SNP) (rs58542926) of the transmembrane 6 superfamily member 2 (TM6SF2) gene in the NCAN-CILP2 region rel...
2 CitationsSource
#1Kyoji Nakajo (Gunma University)H-Index: 1
#2Shuji TakahashiH-Index: 2
Last.Hiroshi Miyashita (Jichi Medical University)H-Index: 19
view all 6 authors...
A noninvasive estimation of central blood-pressure is required by the researchers or the medical practitioners in the cardiovascular field. Up to now, a simulation based approach has been pursued by many researchers and the practical results are obtained. As the progresses in the electrical engineering, the possibility that a wearable central blood-pressure gauge can be realized is increased. This study shows that the aorta model in the cardiovascular simulator can be equivalently transformed to...
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