Asmus Heumann
University of Hamburg
Publications 20
#1Sören Weidemann (UHH: University of Hamburg)H-Index: 3
#2Charlotte Sauer (UHH: University of Hamburg)H-Index: 1
Last.Till Clauditz (UHH: University of Hamburg)H-Index: 13
view all 0 authors...
Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties. PTPN12 expression was analyzed by immunohistochemistry on a tissue microarray with 13,660 clinical prostate cancer specimens. PTPN12 staining was typically absent or weak in normal prostatic epithelium but seen in the majority of cancers, where staining was considered weak in 26.5%, moderate in 39.9%, and strong in 4.7%. High PTPN12 staining was associated with high pT ca...
#1Sarah Minner (UHH: University of Hamburg)H-Index: 27
#2Dominik Hager (UHH: University of Hamburg)
Last.Ronald Simon (UHH: University of Hamburg)H-Index: 48
view all 0 authors...
Abstract Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyzed by immunohistochemistry. Cytoplasmic S100A8 staining was compared to prostate cancer phenotype, patient prognosis and molecular features including TMPRSS2:ERG fusion status and deletions of PTEN, 3p, 5q and 6q. S100A8 immunostaining was ty...
#1Franziska Büscheck (UHH: University of Hamburg)H-Index: 4
#2Maciej Zub (UHH: University of Hamburg)
Last.Andrea Hinsch (UHH: University of Hamburg)H-Index: 7
view all 23 authors...
GATA2 is a pioneering transcription factor governing androgen receptor expression and signaling in prostate cells. To understand the prognostic potential of GATA2 assessment in prostate cancer, we ...
#1Björn-Ole Stüben (UHH: University of Hamburg)
#2Asmus Heumann (UHH: University of Hamburg)H-Index: 4
Last.Jun Li (UHH: University of Hamburg)H-Index: 18
view all 5 authors...
Various approaches have been described for the reconstruction of the portal vein (PV), superior mesenteric vein (SMV), and the inferior vena cava (IVC). We present the use of the recanalized remnant umbilical vein in various settings including transplantation, major liver resection, and pancreatic surgery. We retrospectively analyzed four cases, in which a recanalized remnant umbilical vein was used for vascular reconstruction. The graft harvesting, size of the graft, technique of application, a...
#1Marie-Christine Heinrich (UHH: University of Hamburg)H-Index: 1
#2Cosima Göbel (UHH: University of Hamburg)H-Index: 3
Last.Eike Burandt (UHH: University of Hamburg)H-Index: 11
view all 17 authors...
Background Prostate Stem Cell Antigen (PSCA) is frequently expressed in prostate cancer but its exact function is unclear.
#1Tarik Ghadban (UHH: University of Hamburg)H-Index: 5
#2Matthias Reeh (UHH: University of Hamburg)H-Index: 13
Last.Daniel Perez (UHH: University of Hamburg)H-Index: 5
view all 8 authors...
Minimally invasive surgery (MIS) has superior short-term outcomes than open surgery (OS) for colorectal cancer (CRC). However, a nationwide dataset has not been analysed to confirm these findings. We evaluated the distribution and outcomes of MIS for CRC from 2005 to 2015; all in-patients with CRC surgery procedure codes were identified from hospital data, which are entered into the nationwide diagnosis-related group database and forwarded anonymised to the Federal Bureau of Statistics. We deter...
#1Katharina Grupp (UHH: University of Hamburg)H-Index: 15
#2Faik G. Uzunoglu (UHH: University of Hamburg)H-Index: 11
Last.Gerrit Wolters-Eisfeld (UHH: University of Hamburg)H-Index: 8
view all 17 authors...
The function of Forkhead box O 1 (FOXO1) and pSerine256-FOXO1 immunostaining in esophageal cancer is unclear. To clarify the prognostic role of nuclear FOXO1 and cytoplasmic pSerine256-FOXO1 immunostaining, a tissue microarray containing more than 600 esophageal cancers was analyzed. In non-neoplastic esophageal mucosae, FOXO1 expression was detectable in low and pSerine256-FOXO1 expression in high intensities. Increased FOXO1 and decreased pSerine256-FOXO1 expression were linked to advanced tum...