Don Husereau
University of Ottawa
Health careAlternative medicineHealth technologyEconomic evaluationMedicine
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Publications 82
#1Doreen Anuli Ezeife (TBCC: Tom Baker Cancer Centre)H-Index: 2
#2Francois DionneH-Index: 7
Last. Natasha B. Leighl (Princess Margaret Cancer Centre)H-Index: 48
view all 19 authors...
BACKGROUND: Globally, the rising cost of anticancer therapy has motivated efforts to quantify the overall value of new cancer treatments. Multicriteria decision analysis offers a novel approach to incorporate multiple criteria and perspectives into value assessment. METHODS: The authors recruited a diverse, multistakeholder group who identified and weighted key criteria to establish the drug assessment framework (DAF). Construct validity assessed the degree to which DAF scores were associated wi...
#1Arnaud Bourdin (University of Montpellier)H-Index: 29
#2Don Husereau (U of O: University of Ottawa)H-Index: 20
Last. Xiao Xu (AstraZeneca)H-Index: 4
view all 7 authors...
BACKGROUND: Oral corticosteroid (OCS) treatment for severe asthma is associated with substantial disease burden. Thus, OCS dosage reduction is desirable. Relative efficacy of biologics in reducing OCS treatment for severe, uncontrolled asthma is not fully characterized. OBJECTIVE: We performed a matching-adjusted indirect comparison (MAIC) to assess the relative effects on OCS treatment reduction of three biologic asthma treatments. METHODS: In MAIC of benralizumab vs. mepolizumab and vs. dupilu...
#1Lisa Caulley (Ottawa Hospital Research Institute)H-Index: 5
#2Ferrán Catalá-López (University of Valencia)H-Index: 45
Last. David Moher (Ottawa Hospital Research Institute)H-Index: 74
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Abstract Objectives Appropriate use of reporting guidelines of health research ensures that articles present readers with a consistent representation of study relevance, methodology and results. This study evaluated the use of major reporting guidelines. Study Design and Setting A cross-sectional analysis of health research articles citing four major reporting guidelines indexed in the Web of Science Core Collection (up to June 24, 2018). Two independent reviews were performed in a random sample...
1 CitationsSource
#2Lisa CaulleyH-Index: 5
Last. Ricard MeneuH-Index: 2
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Introduction There has been a growing awareness of the need for rigorously and transparent reported health research, to ensure the reproducibility of studies by future researchers. Health economic evaluations, the comparative analysis of alternative interventions in terms of their costs and consequences, have been promoted as an important tool to inform decision-making. The objective of this study will be to investigate the extent to which articles of economic evaluations of healthcare intervent...
1 CitationsSource
#1Chiranjeev Sanyal (AmeriCorps VISTA)
#1Chiranjeev SanyalH-Index: 4
Last. Don Husereau (U of O: University of Ottawa)H-Index: 20
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Background Community pharmacists’ scope of practice has been evolving from a traditional dispensing role to providing patient-centered services. Given the constraints in healthcare budget and a need for efficient use of finite resources, decision makers may require convincing evidence of value to recommend these services for public funding. Several economic evaluations have aimed to demonstrate the value of services provided by community pharmacists.
#1Chiranjeev SanyalH-Index: 1
#2Don Husereau (U of O: University of Ottawa)H-Index: 20
ABSTRACT Objectives To conduct a systematic review of cost-utility studies of community-based services provided by pharmacists and to examine their reporting and methodological quality. Methods A comprehensive literature search was performed in February 2019 using a replicable search strategy in bibliographic databases MEDLINE, EMBASE, and the NHS Economic Evaluations Database from their inception onwards. Two reviewers independently screened the literature, abstracted data from full-text articl...
1 CitationsSource
#1Prasad Jetty (Ottawa Hospital)H-Index: 1
#2Don Husereau (U of O: University of Ottawa)H-Index: 20
Last. Sudhir Nagpal (Ottawa Hospital)H-Index: 6
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Abstract Background Although the absence of aneurysm-related mortality, postimplantation rupture, and reintervention after EVAR is desirable, it may not necessarily reflect successful aneurysm sac exclusion. Sac regression may be a more sensitive marker for EVAR success and may be influenced by factors beyond the presence or absence of an endoleak. The objective of this study is to determine the rate of overall long-term sac regression after EVAR and the influence of nonanatomic factors, and end...
#1Arnaud BourdinH-Index: 29
#2Don HusereauH-Index: 20
Last. Xiao XuH-Index: 4
view all 7 authors...
Background: Relative efficacy of biologics in reducing oral corticosteroid (OCS) use in severe asthma is not fully characterized. Aims and Objectives: To perform matching-adjusted indirect comparisons (MAIC) of benralizumab vs. mepolizumab and vs. dupilumab in reducing OCS and exacerbation rates in severe asthma. Methods: Patient-level data for the benralizumab ZONDA trial were weighted to match treatment effect–modifying patient characteristics in trials for mepolizumab (SIRIUS) and dupilumab (...
#1Michael J. Zoratti (McMaster University)H-Index: 2
#2Ting Zhou (McMaster University)
Last. Feng Xie (McMaster University)H-Index: 28
view all 10 authors...
Background. Treatment options in oncology are rapidly advancing, and public payer systems are increasingly under pressure to adopt new but expensive cancer treatments. Cost-utility analyses (CUAs) ...
#1Chiranjeev SanyalH-Index: 4
#2Don Husereau (U of O: University of Ottawa)H-Index: 20
Last. Ross T. Tsuyuki (U of A: University of Alberta)H-Index: 53
view all 5 authors...
Urinary tract infections (UTI) are one of the most common infections treated in primary care and the emergency department. The RxOUTMAP study demonstrated that management of uncomplicated UTI by community pharmacists resulted in high clinical cure rates similar to those reported in the literature and a high degree of patient satisfaction. The objective of this study was to assess the cost-effectiveness and budget impact of community pharmacist-initiated compared to family or emergency physician-...
1 CitationsSource