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Terri H. Beaty
Johns Hopkins University
408Publications
70H-index
19.4kCitations
Publications 408
Newest
#1Michelle Daya (University of Colorado Denver)H-Index: 9
#2Nicholas Rafaels (University of Colorado Denver)H-Index: 29
Last.Genevieve L. Wojcik (Stanford University)H-Index: 9
view all 65 authors...
Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genome-wide association studies (GWAS) has been inadequate, and true associations in these underrepresented minority groups have been inconclusive. We report the results of a genome-wide meta-analysis from the Consortium on Asthma among African Ancestry Populations (CAAPA; 7009 asthma cases, 7645 controls). We find ...
#1Meher Preethi Boorgula (University of Colorado Denver)H-Index: 7
#2Margaret A. Taub (Johns Hopkins University)H-Index: 16
Last.Jinshui Fan (Johns Hopkins University)H-Index: 11
view all 21 authors...
Although epigenetic mechanisms are important risk factors for allergic disease, few studies have evaluated DNA methylation differences associated with atopic dermatitis (AD), and none has focused on AD with eczema herpeticum (ADEH+). We will determine how methylation varies in AD individuals with/without EH and associated traits. We modeled differences in genome-wide DNA methylation in whole blood cells from 90 ADEH+, 83 ADEH−, and 84 non-atopic, healthy control subjects, replicating in 36 ADEH+...
#1Woori Kim (Johns Hopkins University)
#2Michael H. Cho (Brigham and Women's Hospital)H-Index: 34
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 70
view all 8 authors...
Background Emphysema, characterized by lung destruction, is a key component of Chronic Obstructive Pulmonary Disease (COPD) and is associated with increased morbidity and mortality. Genome-wide association studies (GWAS) have identified multiple genetic factors associated with cross-sectional measures of quantitative emphysema, but the genetic determinants of longitudinal change in quantitative measures of emphysema remain largely unknown. Our study aims to identify genetic variants associated w...
#1Victor KimH-Index: 21
#2Huaqing Zhao (TU: Temple University)H-Index: 4
Last.Edwin K. SilvermanH-Index: 90
view all 154 authors...
Background Chronic bronchitis (CB) increases risk of COPD exacerbations. We have shown that the St. George’s Respiratory Questionnaire (SGRQ) CB definition identifies patients with a similar clinical phenotype as classically defined CB. Whether the SGRQ CB definition is a predictor of future COPD exacerbations is unknown. Methods We analyzed 7,557 smokers with normal spirometry and Global Initiative for Chronic Obstructive Lung Disease stage 1-4 COPD in the Genetic Epidemiology of COPD study wit...
#1Margaret F Ragland (CU: University of Colorado Boulder)
#2Christopher J Benway (Brigham and Women's Hospital)
Last.Dawn L. DeMeoH-Index: 44
view all 15 authors...
Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that is influenced by both genetic and environmental factors. For many years, knowledge of the genetic basis of COPD...
#1Priya Duggal (Johns Hopkins University)H-Index: 32
#2Christine Marie Ladd-Acosta (Johns Hopkins University)H-Index: 17
Last.Terri H. Beaty (Johns Hopkins University)H-Index: 70
view all 4 authors...
#1Nandita Mukhopadhyay (University of Pittsburgh)H-Index: 7
#2Madison Bishop (Emory University)
Last.George L. Wehby (UI: University of Iowa)H-Index: 23
view all 19 authors...
Orofacial clefts (OFCs) are one of the most common birth defects worldwide and create a significant health burden. The majority of OFCs are non-syndromic, and the genetic component has been only partially determined. Here, we analyze whole genome sequence (WGS) data for association with risk of OFCs in European and Colombian families selected from a multicenter family-based OFC study. Part of the Gabriella Miller Kids First Pediatric Research Program, this is the first large-scale WGS study of O...
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