Bennet J. McComish
University of Tasmania
GeneGenomeMitochondrial DNAGeneticsBiology
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Publications 15
#1Bennet J. McComish (UTAS: University of Tasmania)H-Index: 5
#2Michael A. Charleston (UTAS: University of Tasmania)H-Index: 25
Last. David M. Lambert (Griffith University)H-Index: 41
view all 10 authors...
Microsatellites are widely used in population genetics, but their evolutionary dynamics remain poorly understood. It is unclear whether microsatellite loci drift in length over time. We identify more than 27 million microsatellites using a novel and unique dataset of modern and ancient Adelie penguin genomes along with data from 63 published chordate genomes. We investigate microsatellite evolutionary dynamics over two time scales: one based on the Adelie penguin samples dating to approximately ...
#1Bennet J. McComish (UTAS: University of Tasmania)H-Index: 5
#2Srujana Sahebjada (University of Melbourne)H-Index: 6
Last. Kathryn P. Burdon (UTAS: University of Tasmania)H-Index: 41
view all 22 authors...
Importance Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affecting refraction and vision. It is a major indication for corneal transplant. To discover new genetic loci associated with keratoconus and better understand the causative mechanism of this disease, we performed a genome-wide association study on patients with keratoconus. Objective To identify genetic susceptibility regions for keratoconus in the human genome. Design, Sett...
#1Ebony Liu (Flinders Medical Centre)H-Index: 4
#2Georgia Kaidonis (Flinders Medical Centre)H-Index: 8
Last. Kathryn P. Burdon (UTAS: University of Tasmania)H-Index: 41
view all 17 authors...
Purpose: Few studies have explored the association of genetic variants in microRNA genes and binding sites with diabetic retinopathy (DR) in type 1 diabetes. We conducted a genome-wide scan for single nucleotide polymorphisms (SNPs) in these genes by using data from a genome-wide association study (GWAS). Methods: All known SNPs were imputed from our GWAS data (n = 325) of DR cases and diabetic controls (no DR). Relevant SNPS were extracted using miRNASNP and PolymiRTS (version 2) databases. χ2 ...
#1Ming Lu (UTAS: University of Tasmania)H-Index: 5
#2Bennet J. McComish (UTAS: University of Tasmania)H-Index: 5
Last. Heinrich Körner (UTAS: University of Tasmania)H-Index: 40
view all 5 authors...
A super-enhancer (SE) is a cluster of enhancers with a relatively high density of particular chromatin features. SEs typically regulate key genes that can determine cell identity and differentiation. Identifying SEs and their effects may be critical in predicting key regulatory genes, such as master transcription factor genes or oncogenes. Signal inducible SEs are dense stretches of signal terminal transcription factor (TF) binding regions, and may modulate the interaction between environmental ...
1 CitationsSource
#1Kathryn P. BurdonH-Index: 41
#2Bennet J. McComishH-Index: 5
Last. Jac CharlesworthH-Index: 23
view all 3 authors...
There are many advantages to understanding the genetics of human disease. Genetic markerscan be used to calculate the risk of developing a disease, and elucidation of genetic risk factors can pinpointthe molecular aetiology of disease, which can facilitate the development of targeted therapies. Diabeticretinopathy (DR) is a common complication of diabetes that has a significant impact on quality of life.It has a clear genetic component, but determination of the genetic risk factors has proven di...
#1Ebony Liu (Flinders University)H-Index: 4
#2Georgia Kaidonis (Flinders University)H-Index: 8
Last. Kathryn P. Burdon (UTAS: University of Tasmania)H-Index: 41
view all 10 authors...
#1Kathryn P. Burdon (UTAS: University of Tasmania)H-Index: 41
#2Bennet J. McComish (UTAS: University of Tasmania)H-Index: 5
Last. Jamie E. Craig (Flinders University)H-Index: 56
view all 15 authors...
#1William G. Dodt (QUT: Queensland University of Technology)H-Index: 3
#2Bennet J. McComish (UTAS: University of Tasmania)H-Index: 5
Last. Matthew J. Phillips (QUT: Queensland University of Technology)H-Index: 32
view all 6 authors...
AbstractWe present the complete mitochondrial genome (accession number: LK995454) of an iconic Australian species, the eastern grey kangaroo (Macropus giganteus). The mitogenomic organization is consistent with other marsupials, encoding 13 protein-coding genes, 22 tRNA genes, 2 ribosomal RNA genes, an origin of light strand replication and a control region or D-loop. No repetitive sequences were detected in the control region. The M. giganteus mitogenome exemplifies a combination of tRNA gene o...
3 CitationsSource
#1M DewsburyH-Index: 3
#2T LawH-Index: 1
Last. A Soudan
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This scoping report was instigated by the Australian Building Codes Board (ABCB) in response to concern raised by building regulation stakeholders that new Class 1 and Class 2 buildings were experiencing unacceptable levels of condensation and mould. The persistent presence of condensation in buildings is linked to negative impacts on human health and amenity, as well as building structural integrity. Many factors within the design, construction and building occupation can contribute to the pres...
#1Gillian C. Gibb (Massey University)H-Index: 17
#2Ryan England (Massey University)H-Index: 1
Last. David Penny (Massey University)H-Index: 65
view all 8 authors...
Passerines are the largest avian order, and the 6,000 species comprise more than half of all extant bird species. This successful radiation probably had its origin in the Australasian region, but dating this origin has been difficult due to a scarce fossil record and poor biogeographic assumptions. Many of New Zealand’s endemic passerines fall within the deeper branches of the passerine radiation, and a well resolved phylogeny for the modern New Zealand element in the deeper branches of the osci...
22 CitationsSource